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Mechanisms of NOD-like receptor-associated inflammasome activation.

Wen H, Miao EA, Ting JP.

Immunity. 2013 Sep 19;39(3):432-41. doi: 10.1016/j.immuni.2013.08.037. Review.


The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.

Zhao Y, Yang J, Shi J, Gong YN, Lu Q, Xu H, Liu L, Shao F.

Nature. 2011 Sep 14;477(7366):596-600. doi: 10.1038/nature10510.


The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis.

Franchi L, Eigenbrod T, Muñoz-Planillo R, Nuñez G.

Nat Immunol. 2009 Mar;10(3):241-7. doi: 10.1038/ni.1703. Review.


Inflammasomes: guardians of cytosolic sanctity.

Lamkanfi M, Dixit VM.

Immunol Rev. 2009 Jan;227(1):95-105. doi: 10.1111/j.1600-065X.2008.00730.x. Review.


Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes.

Maier NK, Crown D, Liu J, Leppla SH, Moayeri M.

J Immunol. 2014 Jan 15;192(2):763-70. doi: 10.4049/jimmunol.1301434. Epub 2013 Dec 13.


Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.

Kofoed EM, Vance RE.

Nature. 2011 Aug 28;477(7366):592-5. doi: 10.1038/nature10394.


The CARD plays a critical role in ASC foci formation and inflammasome signalling.

Proell M, Gerlic M, Mace PD, Reed JC, Riedl SJ.

Biochem J. 2013 Feb 1;449(3):613-21. doi: 10.1042/BJ20121198.


Immunology: recognition of a unique partner.

Monack DM.

Nature. 2011 Sep 28;477(7366):543-4. doi: 10.1038/477543a. No abstract available.


Investigating the role of nucleotide-binding oligomerization domain-like receptors in bacterial lung infection.

Leissinger M, Kulkarni R, Zemans RL, Downey GP, Jeyaseelan S.

Am J Respir Crit Care Med. 2014 Jun 15;189(12):1461-8. doi: 10.1164/rccm.201311-2103PP. Review.


Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1β production in acute glaucoma.

Chi W, Li F, Chen H, Wang Y, Zhu Y, Yang X, Zhu J, Wu F, Ouyang H, Ge J, Weinreb RN, Zhang K, Zhuo Y.

Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11181-6. doi: 10.1073/pnas.1402819111. Epub 2014 Jul 14.


Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.

Man SM, Hopkins LJ, Nugent E, Cox S, Glück IM, Tourlomousis P, Wright JA, Cicuta P, Monie TP, Bryant CE.

Proc Natl Acad Sci U S A. 2014 May 20;111(20):7403-8. doi: 10.1073/pnas.1402911111. Epub 2014 May 6.


Novel role of PKR in inflammasome activation and HMGB1 release.

Lu B, Nakamura T, Inouye K, Li J, Tang Y, Lundbäck P, Valdes-Ferrer SI, Olofsson PS, Kalb T, Roth J, Zou Y, Erlandsson-Harris H, Yang H, Ting JP, Wang H, Andersson U, Antoine DJ, Chavan SS, Hotamisligil GS, Tracey KJ.

Nature. 2012 Aug 30;488(7413):670-4. doi: 10.1038/nature11290.


β-arrestin1 is critical for the full activation of NLRP3 and NLRC4 inflammasomes.

Mao K, Chen S, Wang Y, Zeng Y, Ma Y, Hu Y, Zhang H, Sun S, Wu X, Meng G, Pei G, Sun B.

J Immunol. 2015 Feb 15;194(4):1867-73. doi: 10.4049/jimmunol.1401989. Epub 2015 Jan 12.


Sensing bacterial infections by NAIP receptors in NLRC4 inflammasome activation.

Gong YN, Shao F.

Protein Cell. 2012 Feb;3(2):98-105. doi: 10.1007/s13238-012-2028-3. Epub 2012 Mar 17. Review.


Differential requirements for NAIP5 in activation of the NLRC4 inflammasome.

Lightfield KL, Persson J, Trinidad NJ, Brubaker SW, Kofoed EM, Sauer JD, Dunipace EA, Warren SE, Miao EA, Vance RE.

Infect Immun. 2011 Apr;79(4):1606-14. doi: 10.1128/IAI.01187-10. Epub 2011 Jan 31.


The inflammasome in pathogen recognition and inflammation.

Sutterwala FS, Ogura Y, Flavell RA.

J Leukoc Biol. 2007 Aug;82(2):259-64. Epub 2007 Apr 30. Review.


TLR activation regulates damage-associated molecular pattern isoforms released during pyroptosis.

Nyström S, Antoine DJ, Lundbäck P, Lock JG, Nita AF, Högstrand K, Grandien A, Erlandsson-Harris H, Andersson U, Applequist SE.

EMBO J. 2013 Jan 9;32(1):86-99. doi: 10.1038/emboj.2012.328. Epub 2012 Dec 7. Erratum in: EMBO J. 2013 Jan 9;32(1):172.


Inflammasomes in liver diseases.

Szabo G, Csak T.

J Hepatol. 2012 Sep;57(3):642-54. doi: 10.1016/j.jhep.2012.03.035. Epub 2012 May 23. Review.


Cholera toxin, and the related nontoxic adjuvants mmCT and dmLT, promote human Th17 responses via cyclic AMP-protein kinase A and inflammasome-dependent IL-1 signaling.

Larena M, Holmgren J, Lebens M, Terrinoni M, Lundgren A.

J Immunol. 2015 Apr 15;194(8):3829-39. doi: 10.4049/jimmunol.1401633. Epub 2015 Mar 18.

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