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Items: 1 to 20 of 79

1.

Structure-activity studies of divin: an inhibitor of bacterial cell division.

Zhou M, Eun YJ, Guzei IA, Weibel DB.

ACS Med Chem Lett. 2013 Sep 12;4(9):880-885.

2.

Divin: a small molecule inhibitor of bacterial divisome assembly.

Eun YJ, Zhou M, Kiekebusch D, Schlimpert S, Trivedi RR, Bakshi S, Zhong Z, Wahlig TA, Thanbichler M, Weibel DB.

J Am Chem Soc. 2013 Jul 3;135(26):9768-76. doi: 10.1021/ja404640f. Epub 2013 Jun 18.

3.

Cephalostatin analogues--synthesis and biological activity.

Flessner T, Jautelat R, Scholz U, Winterfeldt E.

Fortschr Chem Org Naturst. 2004;87:1-80. Review.

PMID:
15079895
4.

Daptomycin-resistant Enterococcus faecalis diverts the antibiotic molecule from the division septum and remodels cell membrane phospholipids.

Tran TT, Panesso D, Mishra NN, Mileykovskaya E, Guan Z, Munita JM, Reyes J, Diaz L, Weinstock GM, Murray BE, Shamoo Y, Dowhan W, Bayer AS, Arias CA.

MBio. 2013 Jul 23;4(4). pii: e00281-13. doi: 10.1128/mBio.00281-13.

5.

Structure activity relationships of peptidic analogs of MyoD for the development of Id1 inhibitors as antiproliferative agents.

Hsiao YC, Yang DL, Hung HL, Lung FD.

J Pept Sci. 2013 Nov;19(11):676-83. doi: 10.1002/psc.2549. Epub 2013 Oct 3.

PMID:
24123584
6.

Mode of action of the quinolone antimicrobial agents.

Hooper DC, Wolfson JS.

Rev Infect Dis. 1988 Jan-Feb;10 Suppl 1:S14-21. Review.

PMID:
2831608
7.

Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ.

Ruiz-Avila LB, Huecas S, Artola M, Vergoñós A, Ramírez-Aportela E, Cercenado E, Barasoain I, Vázquez-Villa H, Martín-Fontecha M, Chacón P, López-Rodríguez ML, Andreu JM.

ACS Chem Biol. 2013 Sep 20;8(9):2072-83. doi: 10.1021/cb400208z. Epub 2013 Jul 31.

PMID:
23855511
8.
10.

Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole and related heterocycles.

Burgeson JR, Moore AL, Gharaibeh DN, Larson RA, Cerruti NR, Amberg SM, Hruby DE, Dai D.

Bioorg Med Chem Lett. 2013 Feb 1;23(3):750-6. doi: 10.1016/j.bmcl.2012.11.093. Epub 2012 Dec 1.

PMID:
23265900
11.

N-Benzyl-3-sulfonamidopyrrolidines as novel inhibitors of cell division in E. coli.

Mukherjee S, Robinson CA, Howe AG, Mazor T, Wood PA, Urgaonkar S, Hebert AM, Raychaudhuri D, Shaw JT.

Bioorg Med Chem Lett. 2007 Dec 1;17(23):6651-5. Epub 2007 Sep 7.

12.

Development of 4H-pyridopyrimidines: a class of selective bacterial protein synthesis inhibitors.

Guiles JW, Toro A, Ochsner UA, Bullard JM.

Org Med Chem Lett. 2012 Feb 16;2(1):5. doi: 10.1186/2191-2858-2-5.

13.

Novel approaches in the synthesis of batracylin and its analogs: rebirth of an old player?

Dzierzbicka K, Januchta W, Skladanowski A.

Curr Med Chem. 2012;19(26):4475-87. Review.

PMID:
22830346
15.

Design and synthesis of novel imidazole-substituted dipeptide amides as potent and selective inhibitors of Candida albicans myristoylCoA:protein N-myristoyltransferase and identification of related tripeptide inhibitors with mechanism-based antifungal activity.

Devadas B, Freeman SK, Zupec ME, Lu HF, Nagarajan SR, Kishore NS, Lodge JK, Kuneman DW, McWherter CA, Vinjamoori DV, Getman DP, Gordon JI, Sikorski JA.

J Med Chem. 1997 Aug 1;40(16):2609-25.

PMID:
9258368
16.

δ-Carbolines and their ring-opened analogs: synthesis and evaluation against fungal and bacterial opportunistic pathogens.

Mazu TK, Etukala JR, Jacob MR, Khan SI, Walker LA, Ablordeppey SY.

Eur J Med Chem. 2011 Jun;46(6):2378-85. doi: 10.1016/j.ejmech.2011.03.021. Epub 2011 Mar 17.

17.

Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality.

Margalit DN, Romberg L, Mets RB, Hebert AM, Mitchison TJ, Kirschner MW, RayChaudhuri D.

Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11821-6. Epub 2004 Aug 2. Erratum in: Proc Natl Acad Sci U S A. 2004 Sep 21;101(38):13969.

18.

The effects of ring-size analogs of the antimicrobial peptide gramicidin S on phospholipid bilayer model membranes and on the growth of Acholeplasma laidlawii B.

Kiricsi M, Prenner EJ, Jelokhani-Niaraki M, Lewis RN, Hodges RS, McElhaney RN.

Eur J Biochem. 2002 Dec;269(23):5911-20.

19.

Synthesis and biological evaluation of novel analogues of the pan class I phosphatidylinositol 3-kinase (PI3K) inhibitor 2-(difluoromethyl)-1-[4,6-di(4-morpholinyl)-1,3,5-triazin-2-yl]-1H-benzimidazole (ZSTK474).

Rewcastle GW, Gamage SA, Flanagan JU, Frederick R, Denny WA, Baguley BC, Kestell P, Singh R, Kendall JD, Marshall ES, Lill CL, Lee WJ, Kolekar S, Buchanan CM, Jamieson SM, Shepherd PR.

J Med Chem. 2011 Oct 27;54(20):7105-26. doi: 10.1021/jm200688y. Epub 2011 Sep 27.

PMID:
21882832
20.

The relationship between Taxol and (+)-discodermolide: synthetic analogs and modeling studies.

Martello LA, LaMarche MJ, He L, Beauchamp TJ, Smith AB, Horwitz SB.

Chem Biol. 2001 Sep;8(9):843-55.

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