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Items: 1 to 20 of 89


Improved leptin sensitivity as a potential candidate responsible for the spontaneous food restriction of the Lou/C rat.

Veyrat-Durebex C, Poher AL, Caillon A, Somm E, Vallet P, Charnay Y, Rohner-Jeanrenaud F.

PLoS One. 2013 Sep 6;8(9):e73452. doi: 10.1371/journal.pone.0073452. eCollection 2013.


Lack of starvation-induced activation of AMP-activated protein kinase in the hypothalamus of the Lou/C rats resistant to obesity.

Taleux N, De Potter I, Deransart C, Lacraz G, Favier R, Leverve XM, Hue L, Guigas B.

Int J Obes (Lond). 2008 Apr;32(4):639-47. Epub 2007 Dec 4.


Circulating hormones and hypothalamic energy balance: regulatory gene expression in the Lou/C and Wistar rats.

Mitchell SE, Nogueiras R, Rance K, Rayner DV, Wood S, Dieguez C, Williams LM.

J Endocrinol. 2006 Sep;190(3):571-9.


Delayed age-associated decrease in growth hormone pulsatile secretion and increased orexigenic peptide expression in the Lou C/JaLL rat.

Kappeler L, Zizzari P, Alliot J, Epelbaum J, Bluet-Pajot MT.

Neuroendocrinology. 2004;80(5):273-83. Epub 2005 Jan 25.


The Lou/C rat: a model of spontaneous food restriction associated with improved insulin sensitivity and decreased lipid storage in adipose tissue.

Veyrat-Durebex C, Montet X, Vinciguerra M, Gjinovci A, Meda P, Foti M, Rohner-Jeanrenaud F.

Am J Physiol Endocrinol Metab. 2009 May;296(5):E1120-32. doi: 10.1152/ajpendo.90592.2008. Epub 2009 Feb 10.


Suppressor of cytokine signaling 3 knockdown in the mediobasal hypothalamus: counterintuitive effects on energy balance.

de Backer MW, Brans MA, van Rozen AJ, van der Zwaal EM, Luijendijk MC, Garner KG, de Krom M, van Beekum O, la Fleur SE, Adan RA.

J Mol Endocrinol. 2010 Nov;45(5):341-53. doi: 10.1677/JME-10-0057. Epub 2010 Sep 6.


Leptin resistance and desensitization of hypophagia during prolonged inflammatory challenge.

Borges BC, Rorato R, Avraham Y, da Silva LE, Castro M, Vorobiav L, Berry E, Antunes-Rodrigues J, Elias LL.

Am J Physiol Endocrinol Metab. 2011 May;300(5):E858-69. doi: 10.1152/ajpendo.00558.2010. Epub 2011 Feb 22.


Obesity-prone rats have normal blood-brain barrier transport but defective central leptin signaling before obesity onset.

Levin BE, Dunn-Meynell AA, Banks WA.

Am J Physiol Regul Integr Comp Physiol. 2004 Jan;286(1):R143-50. Epub 2003 Sep 4.


Neuronal suppressor of cytokine signaling-3 deficiency enhances hypothalamic leptin-dependent phosphatidylinositol 3-kinase signaling.

Metlakunta AS, Sahu M, Yasukawa H, Dhillon SS, Belsham DD, Yoshimura A, Sahu A.

Am J Physiol Regul Integr Comp Physiol. 2011 May;300(5):R1185-93. doi: 10.1152/ajpregu.00794.2010. Epub 2011 Feb 16.


Signaling through Tyr985 of leptin receptor as an age/diet-dependent switch in the regulation of energy balance.

You J, Yu Y, Jiang L, Li W, Yu X, Gonzalez L, Yang G, Ke Z, Li W, Li C, Liu Y.

Mol Cell Biol. 2010 Apr;30(7):1650-9. doi: 10.1128/MCB.01307-09. Epub 2010 Jan 19.


Over-expression of leptin receptors in hypothalamic POMC neurons increases susceptibility to diet-induced obesity.

Gamber KM, Huo L, Ha S, Hairston JE, Greeley S, Bjørbæk C.

PLoS One. 2012;7(1):e30485. doi: 10.1371/journal.pone.0030485. Epub 2012 Jan 20.


Exercise training improves leptin sensitivity in peripheral tissue of obese rats.

Kang S, Kim KB, Shin KO.

Biochem Biophys Res Commun. 2013 Jun 7;435(3):454-9. doi: 10.1016/j.bbrc.2013.05.007. Epub 2013 May 11.


Postnatal early overfeeding induces hypothalamic higher SOCS3 expression and lower STAT3 activity in adult rats.

Rodrigues AL, de Moura EG, Passos MC, Trevenzoli IH, da Conceição EP, Bonono IT, Neto JF, Lisboa PC.

J Nutr Biochem. 2011 Feb;22(2):109-17. doi: 10.1016/j.jnutbio.2009.11.013. Epub 2010 Mar 20.


Maintenance of the thyroid axis during diet-induced obesity in rodents is controlled at the central level.

Perello M, Cakir I, Cyr NE, Romero A, Stuart RC, Chiappini F, Hollenberg AN, Nillni EA.

Am J Physiol Endocrinol Metab. 2010 Dec;299(6):E976-89. doi: 10.1152/ajpendo.00448.2010. Epub 2010 Sep 21. Erratum in: Am J Physiol Endocrinol Metab. 2011 Feb;300(2):E422.


Inactivation of Socs3 in the hypothalamus enhances the hindbrain response to endogenous satiety signals via oxytocin signaling.

Matarazzo V, Schaller F, Nédélec E, Benani A, Pénicaud L, Muscatelli F, Moyse E, Bauer S.

J Neurosci. 2012 Nov 28;32(48):17097-107. doi: 10.1523/JNEUROSCI.1669-12.2012.


Postnatal early overnutrition changes the leptin signalling pathway in the hypothalamic-pituitary-thyroid axis of young and adult rats.

Rodrigues AL, de Moura EG, Passos MC, Dutra SC, Lisboa PC.

J Physiol. 2009 Jun 1;587(Pt 11):2647-61. doi: 10.1113/jphysiol.2009.169045. Epub 2009 Apr 29.


Hypothalamic suppressor-of-cytokine-signalling 3 mRNA is elevated and pro-opiomelanocortin mRNA is reduced during pregnancy in Brandt's voles (Lasiopodomys brandtii ).

Tang GB, Cui JG, Wang DH.

J Neuroendocrinol. 2008 Sep;20(9):1038-44. doi: 10.1111/j.1365-2826.2008.01764.x. Epub 2008 Jul 11.


Resistance to obesity in Lou/C rats prevents ageing-associated metabolic alterations.

Perrin D, Soulage C, Pequignot JM, Géloën A.

Diabetologia. 2003 Nov;46(11):1489-96. Epub 2003 Sep 4.


Lentiviral vector-mediated knockdown of SOCS3 in the hypothalamus protects against the development of diet-induced obesity in rats.

Liu ZJ, Bian J, Zhao YL, Zhang X, Zou N, Li D.

Diabetes Obes Metab. 2011 Oct;13(10):885-92. doi: 10.1111/j.1463-1326.2011.01419.x.

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