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Results: 1 to 20 of 121

1.

Role of CXCL12/CXCR4 signaling axis in pancreatic cancer.

Wu PF, Lu ZP, Cai BB, Tian L, Zou C, Jiang KR, Miao Y.

Chin Med J (Engl). 2013;126(17):3371-4. Review.

PMID:
24033967
[PubMed - indexed for MEDLINE]
Free Article
2.

CXCL12/CXCR4 protein signaling axis induces sonic hedgehog expression in pancreatic cancer cells via extracellular regulated kinase- and Akt kinase-mediated activation of nuclear factor κB: implications for bidirectional tumor-stromal interactions.

Singh AP, Arora S, Bhardwaj A, Srivastava SK, Kadakia MP, Wang B, Grizzle WE, Owen LB, Singh S.

J Biol Chem. 2012 Nov 9;287(46):39115-24. doi: 10.1074/jbc.M112.409581. Epub 2012 Sep 20.

PMID:
22995914
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

CXCL12-CXCR4 promotes proliferation and invasion of pancreatic cancer cells.

Shen B, Zheng MQ, Lu JW, Jiang Q, Wang TH, Huang XE.

Asian Pac J Cancer Prev. 2013;14(9):5403-8.

PMID:
24175834
[PubMed - indexed for MEDLINE]
Free Article
4.

The CXCR4-CXCL12 pathway facilitates the progression of pancreatic cancer via induction of angiogenesis and lymphangiogenesis.

Cui K, Zhao W, Wang C, Wang A, Zhang B, Zhou W, Yu J, Sun Z, Li S.

J Surg Res. 2011 Nov;171(1):143-50. doi: 10.1016/j.jss.2010.03.001. Epub 2010 Mar 26.

PMID:
20462600
[PubMed - indexed for MEDLINE]
5.

Chemokine receptor CXCR4: role in gastrointestinal cancer.

Lombardi L, Tavano F, Morelli F, Latiano TP, Di Sebastiano P, Maiello E.

Crit Rev Oncol Hematol. 2013 Dec;88(3):696-705. doi: 10.1016/j.critrevonc.2013.08.005. Epub 2013 Aug 28. Review.

PMID:
24120239
[PubMed - indexed for MEDLINE]
6.

SDF-1α upregulation of MMP-2 is mediated by p38 MAPK signaling in pancreatic cancer cell lines.

Pan F, Ma S, Cao W, Liu H, Chen F, Chen X, Shi R.

Mol Biol Rep. 2013 Jul;40(7):4139-46. doi: 10.1007/s11033-012-2225-4. Epub 2013 May 28.

PMID:
23712777
[PubMed - indexed for MEDLINE]
7.

SDF-1/CXCR4 signaling induces pancreatic cancer cell invasion and epithelial-mesenchymal transition in vitro through non-canonical activation of Hedgehog pathway.

Li X, Ma Q, Xu Q, Liu H, Lei J, Duan W, Bhat K, Wang F, Wu E, Wang Z.

Cancer Lett. 2012 Sep 28;322(2):169-76. doi: 10.1016/j.canlet.2012.02.035. Epub 2012 Mar 23.

PMID:
22450749
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

CXCL12 (SDF-1)/CXCR4 pathway in cancer.

Teicher BA, Fricker SP.

Clin Cancer Res. 2010 Jun 1;16(11):2927-31. doi: 10.1158/1078-0432.CCR-09-2329. Epub 2010 May 18. Review.

PMID:
20484021
[PubMed - indexed for MEDLINE]
Free Article
9.

The role of the CXCR4/CXCL12 axis and its clinical implications in gastric cancer.

Lee HJ, Jo DY.

Histol Histopathol. 2012 Sep;27(9):1155-61. Review.

PMID:
22806902
[PubMed - indexed for MEDLINE]
10.

The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia.

Thomas RM, Kim J, Revelo-Penafiel MP, Angel R, Dawson DW, Lowy AM.

Gut. 2008 Nov;57(11):1555-60. doi: 10.1136/gut.2007.143941. Epub 2008 Jul 29.

PMID:
18664506
[PubMed - indexed for MEDLINE]
11.

PTEN loss mediated Akt activation promotes prostate tumor growth and metastasis via CXCL12/CXCR4 signaling.

Conley-LaComb MK, Saliganan A, Kandagatla P, Chen YQ, Cher ML, Chinni SR.

Mol Cancer. 2013 Jul 31;12(1):85. doi: 10.1186/1476-4598-12-85.

PMID:
23902739
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The CXCL12-CXCR4 chemokine pathway: a novel axis regulates lymphangiogenesis.

Zhuo W, Jia L, Song N, Lu XA, Ding Y, Wang X, Song X, Fu Y, Luo Y.

Clin Cancer Res. 2012 Oct 1;18(19):5387-98. doi: 10.1158/1078-0432.CCR-12-0708. Epub 2012 Aug 29.

PMID:
22932666
[PubMed - indexed for MEDLINE]
Free Article
13.

The role of CXCL12-CXCR4 signaling pathway in pancreatic development.

Katsumoto K, Kume S.

Theranostics. 2013;3(1):11-7. doi: 10.7150/thno.4806. Epub 2013 Jan 12. Review.

PMID:
23382781
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Blockade of SDF-1/CXCR4 signalling inhibits pancreatic cancer progression in vitro via inactivation of canonical Wnt pathway.

Wang Z, Ma Q, Liu Q, Yu H, Zhao L, Shen S, Yao J.

Br J Cancer. 2008 Nov 18;99(10):1695-703. doi: 10.1038/sj.bjc.6604745. Epub 2008 Oct 28.

PMID:
19002187
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Opposing roles of CXCR4 and CXCR7 in breast cancer metastasis.

Hernandez L, Magalhaes MA, Coniglio SJ, Condeelis JS, Segall JE.

Breast Cancer Res. 2011;13(6):R128. doi: 10.1186/bcr3074. Epub 2011 Dec 9.

PMID:
22152016
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells.

Chen G, Chen SM, Wang X, Ding XF, Ding J, Meng LH.

J Biol Chem. 2012 Apr 6;287(15):12132-41. doi: 10.1074/jbc.M111.302299. Epub 2012 Feb 15. Erratum in: J Biol Chem. 2012 Jun 1;287(23):19336.

PMID:
22337890
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems.

Katoh H, Hosono K, Ito Y, Suzuki T, Ogawa Y, Kubo H, Kamata H, Mishima T, Tamaki H, Sakagami H, Sugimoto Y, Narumiya S, Watanabe M, Majima M.

Am J Pathol. 2010 Mar;176(3):1469-83. doi: 10.2353/ajpath.2010.090607. Epub 2010 Jan 28.

PMID:
20110411
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

CXCL12-CXCR4 signalling axis confers gemcitabine resistance to pancreatic cancer cells: a novel target for therapy.

Singh S, Srivastava SK, Bhardwaj A, Owen LB, Singh AP.

Br J Cancer. 2010 Nov 23;103(11):1671-9. doi: 10.1038/sj.bjc.6605968. Epub 2010 Nov 2.

PMID:
21045835
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Chemokine receptor CXCR4 enhances proliferation in pancreatic cancer cells through AKT and ERK dependent pathways.

Shen X, Artinyan A, Jackson D, Thomas RM, Lowy AM, Kim J.

Pancreas. 2010 Jan;39(1):81-7. doi: 10.1097/MPA.0b013e3181bb2ab7.

PMID:
19820417
[PubMed - indexed for MEDLINE]
20.

CXCL8/IL-8 and CXCL12/SDF-1alpha co-operatively promote invasiveness and angiogenesis in pancreatic cancer.

Matsuo Y, Ochi N, Sawai H, Yasuda A, Takahashi H, Funahashi H, Takeyama H, Tong Z, Guha S.

Int J Cancer. 2009 Feb 15;124(4):853-61. doi: 10.1002/ijc.24040.

PMID:
19035451
[PubMed - indexed for MEDLINE]
Free PMC Article

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