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Results: 1 to 20 of 90

Related Citations for PubMed (Select 24027803)

1.

Identification of Selective Inhibitors of Phosphofructokinase as Lead Compounds Against Trypanosomiasis.

Walsh MJ, Brimacombe KR, Vásquez-Valdivieso MG, Auld DS, Simeonov A, Morgan HP, Fothergill-Gilmore LA, Michels PAM, Walkinshaw MD, Shen M, Boxer MB.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2011 Oct 18 [updated 2013 Feb 25].

2.

Identification of ML251, a Potent Inhibitor of T. brucei and T. cruzi Phosphofructokinase.

Brimacombe KR, Walsh MJ, Liu L, Vásquez-Valdivieso MG, Morgan HP, McNae I, Fothergill-Gilmore LA, Michels PA, Auld DS, Simeonov A, Walkinshaw MD, Shen M, Boxer MB.

ACS Med Chem Lett. 2013 Oct 30;5(1):12-7. doi: 10.1021/ml400259d. eCollection 2014 Jan 9.

3.

Identification of Inhibitors of Trypanosoma brucei Hexokinases.

Sharlow E, Golden JE, Dodson H, Morris M, Hesser M, Lyda T, Leimgruber S, Schroeder CE, Flaherty DP, Weiner WS, Simpson D, Lazo JS, Aubé J, Morris JC.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Dec 15 [updated 2011 Jun 24].

4.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
5.

Application of a resazurin-based high-throughput screening assay for the identification and progression of new treatments for human African trypanosomiasis.

Bowling T, Mercer L, Don R, Jacobs R, Nare B.

Int J Parasitol Drugs Drug Resist. 2012 Mar 3;2:262-70. doi: 10.1016/j.ijpddr.2012.02.002. eCollection 2012 Dec.

6.

Identification of compounds with anti-proliferative activity against Trypanosoma brucei brucei strain 427 by a whole cell viability based HTS campaign.

Sykes ML, Baell JB, Kaiser M, Chatelain E, Moawad SR, Ganame D, Ioset JR, Avery VM.

PLoS Negl Trop Dis. 2012;6(11):e1896. doi: 10.1371/journal.pntd.0001896. Epub 2012 Nov 29.

7.

Hit-to-lead development of the chamigrane endoperoxide merulin A for the treatment of African sleeping sickness.

Navarro G, Chokpaiboon S, De Muylder G, Bray WM, Nisam SC, McKerrow JH, Pudhom K, Linington RG.

PLoS One. 2012;7(9):e46172. doi: 10.1371/journal.pone.0046172. Epub 2012 Sep 27.

8.

Toward Improved Therapy for Classic Galactosemia.

Boxer MB, Shen M, Tanega C, Tang M, Lai K, Auld DS.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Mar 18 [updated 2011 Mar 3].

9.

Identification of potent inhibitors of the Trypanosoma brucei methionyl-tRNA synthetase via high-throughput orthogonal screening.

Pedró-Rosa L, Buckner FS, Ranade RM, Eberhart C, Madoux F, Gillespie JR, Koh CY, Brown S, Lohse J, Verlinde CL, Fan E, Bannister T, Scampavia L, Hol WG, Spicer T, Hodder P.

J Biomol Screen. 2015 Jan;20(1):122-30. doi: 10.1177/1087057114548832. Epub 2014 Aug 27.

PMID:
25163684
10.

Stoking the drug target pipeline for human African trypanosomiasis.

Phillips MA.

Mol Microbiol. 2012 Oct;86(1):10-4. doi: 10.1111/mmi.12001. Epub 2012 Aug 28.

11.

A target-based high throughput screen yields Trypanosoma brucei hexokinase small molecule inhibitors with antiparasitic activity.

Sharlow ER, Lyda TA, Dodson HC, Mustata G, Morris MT, Leimgruber SS, Lee KH, Kashiwada Y, Close D, Lazo JS, Morris JC.

PLoS Negl Trop Dis. 2010 Apr 13;4(4):e659. doi: 10.1371/journal.pntd.0000659.

12.

Identification and characterization of hundreds of potent and selective inhibitors of Trypanosoma brucei growth from a kinase-targeted library screening campaign.

Diaz R, Luengo-Arratta SA, Seixas JD, Amata E, Devine W, Cordon-Obras C, Rojas-Barros DI, Jimenez E, Ortega F, Crouch S, Colmenarejo G, Fiandor JM, Martin JJ, Berlanga M, Gonzalez S, Manzano P, Navarro M, Pollastri MP.

PLoS Negl Trop Dis. 2014 Oct 23;8(10):e3253. doi: 10.1371/journal.pntd.0003253. eCollection 2014 Oct.

13.

SCYX-7158, an orally-active benzoxaborole for the treatment of stage 2 human African trypanosomiasis.

Jacobs RT, Nare B, Wring SA, Orr MD, Chen D, Sligar JM, Jenks MX, Noe RA, Bowling TS, Mercer LT, Rewerts C, Gaukel E, Owens J, Parham R, Randolph R, Beaudet B, Bacchi CJ, Yarlett N, Plattner JJ, Freund Y, Ding C, Akama T, Zhang YK, Brun R, Kaiser M, Scandale I, Don R.

PLoS Negl Trop Dis. 2011 Jun;5(6):e1151. doi: 10.1371/journal.pntd.0001151. Epub 2011 Jun 28.

14.

Structure-based design of submicromolar, biologically active inhibitors of trypanosomatid glyceraldehyde-3-phosphate dehydrogenase.

Aronov AM, Suresh S, Buckner FS, Van Voorhis WC, Verlinde CL, Opperdoes FR, Hol WG, Gelb MH.

Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4273-8.

16.

Chemical validation of trypanothione synthetase: a potential drug target for human trypanosomiasis.

Torrie LS, Wyllie S, Spinks D, Oza SL, Thompson S, Harrison JR, Gilbert IH, Wyatt PG, Fairlamb AH, Frearson JA.

J Biol Chem. 2009 Dec 25;284(52):36137-45. doi: 10.1074/jbc.M109.045336. Epub 2009 Oct 14.

17.

Some phosphonic acid analogs as inhibitors of pyrophosphate-dependent phosphofructokinase, a novel target in Toxoplasma gondii.

Peng ZY, Mansour JM, Araujo F, Ju JY, McKenna CE, Mansour TE.

Biochem Pharmacol. 1995 Jan 6;49(1):105-13.

PMID:
7840776
18.

Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection - Probe 3.

Carmody LC, Germain A, Barker D, Galan-Rodriguez C, Bettiol E, Rodriguez A, MacPherson L, Palmer M, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Mar 25 [updated 2011 Mar 11].

19.

Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection - Probe 1.

Carmody LC, Germain A, Barker D, Galan-Rodriguez C, Bettiol E, Rodriguez A, MacPherson L, Palmer M, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Mar 26 [updated 2011 Mar 11].

20.

Identification of Small-Molecule Inhibitors of Trypansoma cruzi Infection.

Carmody LC, Germain A, Barker D, Galan-Rodriguez C, Bettiol E, Rodriguez A, MacPherson L, Palmer M, Schreiber SL.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Mar 25 [updated 2011 Feb 10].

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