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Items: 1 to 20 of 164

1.

MiR-26b, upregulated in Alzheimer's disease, activates cell cycle entry, tau-phosphorylation, and apoptosis in postmitotic neurons.

Absalon S, Kochanek DM, Raghavan V, Krichevsky AM.

J Neurosci. 2013 Sep 11;33(37):14645-59. doi: 10.1523/JNEUROSCI.1327-13.2013.

2.

MicroRNA-125b induces tau hyperphosphorylation and cognitive deficits in Alzheimer's disease.

Banzhaf-Strathmann J, Benito E, May S, Arzberger T, Tahirovic S, Kretzschmar H, Fischer A, Edbauer D.

EMBO J. 2014 Aug 1;33(15):1667-80. doi: 10.15252/embj.201387576. Epub 2014 Jul 7.

3.

Activation of Cdk5/p25 and tau phosphorylation following chronic brain hypoperfusion in rats involves microRNA-195 down-regulation.

Sun LH, Ban T, Liu CD, Chen QX, Wang X, Yan ML, Hu XL, Su XL, Bao YN, Sun LL, Zhao LJ, Pei SC, Jiang XM, Zong DK, Ai J.

J Neurochem. 2015 Sep;134(6):1139-51. doi: 10.1111/jnc.13212.

PMID:
26118667
4.

De-repression of FOXO3a death axis by microRNA-132 and -212 causes neuronal apoptosis in Alzheimer's disease.

Wong HK, Veremeyko T, Patel N, Lemere CA, Walsh DM, Esau C, Vanderburg C, Krichevsky AM.

Hum Mol Genet. 2013 Aug 1;22(15):3077-92. doi: 10.1093/hmg/ddt164. Epub 2013 Apr 11.

5.

Up-regulation of phosphorylated/activated p70 S6 kinase and its relationship to neurofibrillary pathology in Alzheimer's disease.

An WL, Cowburn RF, Li L, Braak H, Alafuzoff I, Iqbal K, Iqbal IG, Winblad B, Pei JJ.

Am J Pathol. 2003 Aug;163(2):591-607. Erratum in: Am J Pathol. 2003 Dec;163(6):2645.

6.

Screening of microRNAs associated with Alzheimer's disease using oxidative stress cell model and different strains of senescence accelerated mice.

Zhang R, Zhang Q, Niu J, Lu K, Xie B, Cui D, Xu S.

J Neurol Sci. 2014 Mar 15;338(1-2):57-64. doi: 10.1016/j.jns.2013.12.017. Epub 2013 Dec 15.

PMID:
24423585
7.

Alteration of the microRNA network during the progression of Alzheimer's disease.

Lau P, Bossers K, Janky R, Salta E, Frigerio CS, Barbash S, Rothman R, Sierksma AS, Thathiah A, Greenberg D, Papadopoulou AS, Achsel T, Ayoubi T, Soreq H, Verhaagen J, Swaab DF, Aerts S, De Strooper B.

EMBO Mol Med. 2013 Oct;5(10):1613-34. doi: 10.1002/emmm.201201974. Epub 2013 Sep 9.

8.

Amyloid-β toxicity and tau hyperphosphorylation are linked via RCAN1 in Alzheimer's disease.

Lloret A, Badia MC, Giraldo E, Ermak G, Alonso MD, Pallardó FV, Davies KJ, Viña J.

J Alzheimers Dis. 2011;27(4):701-9. doi: 10.3233/JAD-2011-110890.

9.
10.

Cell cycle re-entry in Alzheimer's disease: a major neuropathological characteristic?

Lopes JP, Oliveira CR, Agostinho P.

Curr Alzheimer Res. 2009 Jun;6(3):205-12. Review.

PMID:
19519302
12.

ets-2 promotes the activation of a mitochondrial death pathway in Down's syndrome neurons.

Helguera P, Pelsman A, Pigino G, Wolvetang E, Head E, Busciglio J.

J Neurosci. 2005 Mar 2;25(9):2295-303.

13.

Alpha1-antichymotrypsin, an inflammatory protein overexpressed in Alzheimer's disease brain, induces tau phosphorylation in neurons.

Padmanabhan J, Levy M, Dickson DW, Potter H.

Brain. 2006 Nov;129(Pt 11):3020-34. Epub 2006 Sep 20.

14.

MicroRNA-22 (miR-22) overexpression is neuroprotective via general anti-apoptotic effects and may also target specific Huntington's disease-related mechanisms.

Jovicic A, Zaldivar Jolissaint JF, Moser R, Silva Santos Mde F, Luthi-Carter R.

PLoS One. 2013;8(1):e54222. doi: 10.1371/journal.pone.0054222. Epub 2013 Jan 17.

15.
16.

Distinct chronology of neuronal cell cycle re-entry and tau pathology in the 3xTg-AD mouse model and Alzheimer's disease patients.

Hradek AC, Lee HP, Siedlak SL, Torres SL, Jung W, Han AH, Lee HG.

J Alzheimers Dis. 2015;43(1):57-65. doi: 10.3233/JAD-141083.

PMID:
25061053
17.

Activation of Akt/PKB, increased phosphorylation of Akt substrates and loss and altered distribution of Akt and PTEN are features of Alzheimer's disease pathology.

Griffin RJ, Moloney A, Kelliher M, Johnston JA, Ravid R, Dockery P, O'Connor R, O'Neill C.

J Neurochem. 2005 Apr;93(1):105-17.

18.

A Cdk5 inhibitory peptide reduces tau hyperphosphorylation and apoptosis in neurons.

Zheng YL, Kesavapany S, Gravell M, Hamilton RS, Schubert M, Amin N, Albers W, Grant P, Pant HC.

EMBO J. 2005 Jan 12;24(1):209-20. Epub 2004 Dec 9.

19.

Cyclin D1, cdk4, and Bim are involved in thrombin-induced apoptosis in cultured cortical neurons.

Rao HV, Thirumangalakudi L, Desmond P, Grammas P.

J Neurochem. 2007 Apr;101(2):498-505. Epub 2007 Jan 24.

20.

Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease.

Seward ME, Swanson E, Norambuena A, Reimann A, Cochran JN, Li R, Roberson ED, Bloom GS.

J Cell Sci. 2013 Mar 1;126(Pt 5):1278-86. doi: 10.1242/jcs.1125880. Epub 2013 Jan 23.

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