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Items: 1 to 20 of 130

1.

Synthesis of dihydroxymethyl dihydroxypyrrolidines and steviamine analogues from C-2 formyl glycals.

Ansari AA, Vankar YD.

J Org Chem. 2013 Sep 20;78(18):9383-95. doi: 10.1021/jo401613v. Epub 2013 Sep 11.

PMID:
24024728
2.

Concise synthesis of (-)-steviamine and analogues and their glycosidase inhibitory activities.

Jiangseubchatveera N, Bouillon ME, Liawruangrath B, Liawruangrath S, Nash RJ, Pyne SG.

Org Biomol Chem. 2013 Jun 21;11(23):3826-33. doi: 10.1039/c3ob40374b.

PMID:
23640519
3.

Synthesis of isofagomine-pyrrolidine hybrid sugars and analogues of (-)-steviamine and (+)-hyacinthacine C5 using 1,3-dipolar cycloaddition reactions.

Lahiri R, Palanivel A, Kulkarni SA, Vankar YD.

J Org Chem. 2014 Nov 21;79(22):10786-800. doi: 10.1021/jo5016745. Epub 2014 Nov 4.

PMID:
25333970
4.

Synthesis and glycosidase inhibition of the enantiomer of (-)-steviamine, the first example of a new class of indolizidine alkaloid.

Hu XG, Bartholomew B, Nash RJ, Wilson FX, Fleet GW, Nakagawa S, Kato A, Jia YM, van Well R, Yu CY.

Org Lett. 2010 Jun 4;12(11):2562-5. doi: 10.1021/ol1007718.

PMID:
20438104
5.

α-Geminal dihydroxymethyl piperidine and pyrrolidine iminosugars: synthesis, conformational analysis, glycosidase inhibitory activity, and molecular docking studies.

Pawar NJ, Parihar VS, Chavan ST, Joshi R, Joshi PV, Sabharwal SG, Puranik VG, Dhavale DD.

J Org Chem. 2012 Sep 21;77(18):7873-82. Epub 2012 Aug 29.

PMID:
22873702
6.

Total synthesis and glycosidase inhibition of broussonetine I and J(2).

Zhao H, Kato A, Sato K, Jia YM, Yu CY.

J Org Chem. 2013 Aug 16;78(16):7896-902. doi: 10.1021/jo4010553. Epub 2013 Jul 29.

PMID:
23829312
7.

Synthesis of pyrrolidine-based analogues of 2-acetamidosugars as N-acetyl-D-glucosaminidase inhibitors.

Tran AT, Luo B, Jagadeesh Y, Auberger N, Désiré J, Nakagawa S, Kato A, Zhang Y, Blériot Y, Sollogoub M.

Carbohydr Res. 2015 May 29;409:56-62. doi: 10.1016/j.carres.2015.02.014. Epub 2015 Mar 10.

PMID:
25950121
8.

Divergent synthesis of 4-epi-fagomine, 3,4-dihydroxypipecolic acid, and a dihydroxyindolizidine and their β-galactosidase inhibitory and immunomodulatory activities.

Kumar KS, Rathee JS, Subramanian M, Chattopadhyay S.

J Org Chem. 2013 Aug 2;78(15):7406-13. doi: 10.1021/jo400448p. Epub 2013 Jul 15.

PMID:
23806010
10.

Functionalization of glycals leading to 2-deoxy-O-glycosides, aminosugars, nitrosugars and glycosidase inhibitors: our experience.

Lahiri R, Dharuman S, Vankar YD.

Chimia (Aarau). 2012;66(12):905-12. doi: 10.2533/chimia.2012.905. Review.

PMID:
23394274
11.

NHC-mediated cross-coupling of sugar-derived cyclic nitrones with enals: general and efficient synthesis of polyhydroxylated pyrrolizidines and indolizidines.

Xu WY, Iwaki R, Jia YM, Zhang W, Kato A, Yu CY.

Org Biomol Chem. 2013 Jul 28;11(28):4622-39. doi: 10.1039/c3ob40696b. Epub 2013 Jun 7.

PMID:
23749268
12.

Synthesis and biological evaluation of ether bridged bicyclic iminosugar derivatives.

Chir JL, Wu PJ, Zou W, Bhasin M, Juang WF, Guo CQ, Wu AT.

Carbohydr Res. 2009 Sep 8;344(13):1639-45. doi: 10.1016/j.carres.2009.05.029. Epub 2009 Jun 6.

PMID:
19570528
13.

Synthesis of [(2S,3S,4R)-3,4-dihydroxypyrrolidin-2-yl]-5-methylfuran-4-carboxylic acid derivatives: new leads as selective beta-galactosidase inhibitors.

Moreno-Vargas AJ, Demange R, Fuentes J, Robina I, Vogel P.

Bioorg Med Chem Lett. 2002 Sep 2;12(17):2335-9.

PMID:
12161128
14.

Stereoselective synthesis of (2S,3S,4R,5S)-3,4-dihydroxy-2,5-dihydroxymethyl pyrrolidine from L-sorbose.

Balieu S, Guilleret A, Reynaud R, Martinez A, Haudrechy A.

Carbohydr Res. 2013 Jun 7;374:14-22. doi: 10.1016/j.carres.2013.03.017. Epub 2013 Mar 29.

PMID:
23603481
15.

Synthesis and enzymatic evaluation of five-membered iminocyclitols and a pseudodisaccharide.

Saotome C, Kanie Y, Kanie O, Wong CH.

Bioorg Med Chem. 2000 Sep;8(9):2249-61.

PMID:
11026538
16.

Asymmetric synthesis of 3-amino-4-hydroxy-2-(hydroxymethyl)pyrrolidines as potential glycosidase inhibitors.

Curtis KL, Evinson EL, Handa S, Singh K.

Org Biomol Chem. 2007 Nov 7;5(21):3544-53. Epub 2007 Oct 2.

PMID:
17943217
17.

Synthesis and evaluation of eight- and four-membered iminosugar analogues as inhibitors of testicular ceramide-specific glucosyltransferase, testicular β-glucosidase 2, and other glycosidases.

Lee JC, Francis S, Dutta D, Gupta V, Yang Y, Zhu JY, Tash JS, Schönbrunn E, Georg GI.

J Org Chem. 2012 Apr 6;77(7):3082-98. doi: 10.1021/jo202054g. Epub 2012 Mar 20.

18.

Difluoromethylenated polyhydroxylated pyrrolidines: facile synthesis, crystal structure and biological evaluation.

Wang RW, Xu J, Lopez O, Bols M, Qing FL.

Future Med Chem. 2009 Aug;1(5):991-7. doi: 10.4155/fmc.09.82.

PMID:
21426093
19.

Preliminary studies on the transformation of nitrosugars into branched chain iminosugars: synthesis of 1,4-dideoxy-4-C-hydroxymethyl-1,4-imino-pentanols.

Otero JM, Soengas RG, Estévez JC, Estévez RJ, Watkin DJ, Evinson EL, Nash RJ, Fleet GW.

Org Lett. 2007 Feb 15;9(4):623-6.

PMID:
17286369
20.
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