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Items: 1 to 20 of 148

1.

Bit-by-bit autophagic removal of parkin-labelled mitochondria.

Yang JY, Yang WY.

Nat Commun. 2013;4:2428. doi: 10.1038/ncomms3428.

PMID:
24013556
2.

Regulation of mitophagy by the Gp78 E3 ubiquitin ligase.

Fu M, St-Pierre P, Shankar J, Wang PT, Joshi B, Nabi IR.

Mol Biol Cell. 2013 Apr;24(8):1153-62. doi: 10.1091/mbc.E12-08-0607. Epub 2013 Feb 20.

3.

Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy.

Chan NC, Salazar AM, Pham AH, Sweredoski MJ, Kolawa NJ, Graham RL, Hess S, Chan DC.

Hum Mol Genet. 2011 May 1;20(9):1726-37. doi: 10.1093/hmg/ddr048. Epub 2011 Feb 4.

4.

Parkin uses the UPS to ship off dysfunctional mitochondria.

Chan NC, Chan DC.

Autophagy. 2011 Jul;7(7):771-2. Epub 2011 Jul 1.

5.

Optineurin is an autophagy receptor for damaged mitochondria in parkin-mediated mitophagy that is disrupted by an ALS-linked mutation.

Wong YC, Holzbaur EL.

Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4439-48. doi: 10.1073/pnas.1405752111. Epub 2014 Oct 7.

6.

PINK1/Parkin-mediated mitophagy in mammalian cells.

Eiyama A, Okamoto K.

Curr Opin Cell Biol. 2015 Apr;33:95-101. doi: 10.1016/j.ceb.2015.01.002. Epub 2015 Feb 17. Review.

PMID:
25697963
7.

Spatiotemporally controlled initiation of Parkin-mediated mitophagy within single cells.

Yang JY, Yang WY.

Autophagy. 2011 Oct;7(10):1230-8. doi: 10.4161/auto.7.10.16626.

PMID:
22011618
8.

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin.

Tanaka A, Cleland MM, Xu S, Narendra DP, Suen DF, Karbowski M, Youle RJ.

J Cell Biol. 2010 Dec 27;191(7):1367-80. doi: 10.1083/jcb.201007013. Epub 2010 Dec 20.

9.

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both.

Narendra D, Kane LA, Hauser DN, Fearnley IM, Youle RJ.

Autophagy. 2010 Nov;6(8):1090-106.

10.

Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming.

Ding WX, Ni HM, Li M, Liao Y, Chen X, Stolz DB, Dorn GW 2nd, Yin XM.

J Biol Chem. 2010 Sep 3;285(36):27879-90. doi: 10.1074/jbc.M110.119537. Epub 2010 Jun 23.

11.

Disease-causing mutations in parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy.

Lee JY, Nagano Y, Taylor JP, Lim KL, Yao TP.

J Cell Biol. 2010 May 17;189(4):671-9. doi: 10.1083/jcb.201001039. Epub 2010 May 10.

12.

Hepatitis C virus core protein suppresses mitophagy by interacting with parkin in the context of mitochondrial depolarization.

Hara Y, Yanatori I, Ikeda M, Kiyokage E, Nishina S, Tomiyama Y, Toida K, Kishi F, Kato N, Imamura M, Chayama K, Hino K.

Am J Pathol. 2014 Nov;184(11):3026-39. doi: 10.1016/j.ajpath.2014.07.024. Epub 2014 Sep 20.

PMID:
25244949
13.

PINK1 is recruited to mitochondria with parkin and associates with LC3 in mitophagy.

Kawajiri S, Saiki S, Sato S, Sato F, Hatano T, Eguchi H, Hattori N.

FEBS Lett. 2010 Mar 19;584(6):1073-9. doi: 10.1016/j.febslet.2010.02.016. Epub 2010 Feb 12.

14.

Spatial parkin translocation and degradation of damaged mitochondria via mitophagy in live cortical neurons.

Cai Q, Zakaria HM, Simone A, Sheng ZH.

Curr Biol. 2012 Mar 20;22(6):545-52. doi: 10.1016/j.cub.2012.02.005. Epub 2012 Feb 16.

15.

USP8 regulates mitophagy by removing K6-linked ubiquitin conjugates from parkin.

Durcan TM, Tang MY, Pérusse JR, Dashti EA, Aguileta MA, McLelland GL, Gros P, Shaler TA, Faubert D, Coulombe B, Fon EA.

EMBO J. 2014 Nov 3;33(21):2473-91. doi: 10.15252/embj.201489729. Epub 2014 Sep 12.

16.

Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy.

Sun Y, Vashisht AA, Tchieu J, Wohlschlegel JA, Dreier L.

J Biol Chem. 2012 Nov 23;287(48):40652-60. doi: 10.1074/jbc.M112.419721. Epub 2012 Oct 11.

17.

Deubiquitinating enzymes regulate PARK2-mediated mitophagy.

Wang Y, Serricchio M, Jauregui M, Shanbhag R, Stoltz T, Di Paolo CT, Kim PK, McQuibban GA.

Autophagy. 2015 Apr 3;11(4):595-606. doi: 10.1080/15548627.2015.1034408.

18.

Targeted siRNA Screens Identify ER-to-Mitochondrial Calcium Exchange in Autophagy and Mitophagy Responses in RPE1 Cells.

MacVicar TD, Mannack LV, Lees RM, Lane JD.

Int J Mol Sci. 2015 Jun 11;16(6):13356-80. doi: 10.3390/ijms160613356.

19.

Phosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neurons.

Rakovic A, Shurkewitsch K, Seibler P, Grünewald A, Zanon A, Hagenah J, Krainc D, Klein C.

J Biol Chem. 2013 Jan 25;288(4):2223-37. doi: 10.1074/jbc.M112.391680. Epub 2012 Dec 4.

20.

ROS-induced mitochondrial depolarization initiates PARK2/PARKIN-dependent mitochondrial degradation by autophagy.

Wang Y, Nartiss Y, Steipe B, McQuibban GA, Kim PK.

Autophagy. 2012 Oct;8(10):1462-76. doi: 10.4161/auto.21211. Epub 2012 Aug 14.

PMID:
22889933
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