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Results: 1 to 20 of 110

1.

Impaired sense of smell in a Drosophila Parkinson's model.

Poddighe S, Bhat KM, Setzu MD, Solla P, Angioy AM, Marotta R, Ruffilli R, Marrosu F, Liscia A.

PLoS One. 2013 Aug 29;8(8):e73156. doi: 10.1371/journal.pone.0073156. eCollection 2013.

PMID:
24009736
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin.

Clark IE, Dodson MW, Jiang C, Cao JH, Huh JR, Seol JH, Yoo SJ, Hay BA, Guo M.

Nature. 2006 Jun 29;441(7097):1162-6. Epub 2006 May 3.

PMID:
16672981
[PubMed - indexed for MEDLINE]
3.

Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function.

Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt-Weisenhorn D, Van Coster R, Wurst W, Scorrano L, De Strooper B.

EMBO Mol Med. 2009 May;1(2):99-111. doi: 10.1002/emmm.200900006.

PMID:
20049710
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Parkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondria.

Liu S, Sawada T, Lee S, Yu W, Silverio G, Alapatt P, Millan I, Shen A, Saxton W, Kanao T, Takahashi R, Hattori N, Imai Y, Lu B.

PLoS Genet. 2012;8(3):e1002537. doi: 10.1371/journal.pgen.1002537. Epub 2012 Mar 1.

PMID:
22396657
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Nicotine increases lifespan and rescues olfactory and motor deficits in a Drosophila model of Parkinson's disease.

Chambers RP, Call GB, Meyer D, Smith J, Techau JA, Pearman K, Buhlman LM.

Behav Brain Res. 2013 Sep 15;253:95-102. doi: 10.1016/j.bbr.2013.07.020. Epub 2013 Jul 16.

PMID:
23871228
[PubMed - indexed for MEDLINE]
Free Article
6.

Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease.

Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, Deas E, Plun-Favreau H, Nicotera P, Abramov AY, Willis AE, Mallucci GR, Loh SH, Martins LM.

Nat Cell Biol. 2014 Feb;16(2):157-66. doi: 10.1038/ncb2901. Epub 2014 Jan 19.

PMID:
24441527
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Olfactory deficits in an alpha-synuclein fly model of Parkinson's disease.

Chen AY, Xia S, Wilburn P, Tully T.

PLoS One. 2014 May 30;9(5):e97758. doi: 10.1371/journal.pone.0097758. eCollection 2014.

PMID:
24879013
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease.

Costa AC, Loh SH, Martins LM.

Cell Death Dis. 2013 Jan 17;4:e467. doi: 10.1038/cddis.2012.205.

PMID:
23328674
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Drosophila as a model to study mitochondrial dysfunction in Parkinson's disease.

Guo M.

Cold Spring Harb Perspect Med. 2012 Nov 1;2(11). pii: a009944. doi: 10.1101/cshperspect.a009944. Review.

PMID:
23024178
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Pink1 regulates the oxidative phosphorylation machinery via mitochondrial fission.

Liu W, Acín-Peréz R, Geghman KD, Manfredi G, Lu B, Li C.

Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12920-4. doi: 10.1073/pnas.1107332108. Epub 2011 Jul 18.

PMID:
21768365
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Modelling Parkinson's disease in Drosophila.

Botella JA, Bayersdorfer F, Gmeiner F, Schneuwly S.

Neuromolecular Med. 2009;11(4):268-80. doi: 10.1007/s12017-009-8098-6. Epub 2009 Oct 24. Review.

PMID:
19855946
[PubMed - indexed for MEDLINE]
12.

Pink1-deficiency in mice impairs gait, olfaction and serotonergic innervation of the olfactory bulb.

Glasl L, Kloos K, Giesert F, Roethig A, Di Benedetto B, Kühn R, Zhang J, Hafen U, Zerle J, Hofmann A, de Angelis MH, Winklhofer KF, Hölter SM, Vogt Weisenhorn DM, Wurst W.

Exp Neurol. 2012 May;235(1):214-27. doi: 10.1016/j.expneurol.2012.01.002. Epub 2012 Jan 11.

PMID:
22265660
[PubMed - indexed for MEDLINE]
13.

The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila.

Deng H, Dodson MW, Huang H, Guo M.

Proc Natl Acad Sci U S A. 2008 Sep 23;105(38):14503-8. doi: 10.1073/pnas.0803998105. Epub 2008 Sep 17.

PMID:
18799731
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

The yeast complex I equivalent NADH dehydrogenase rescues pink1 mutants.

Vilain S, Esposito G, Haddad D, Schaap O, Dobreva MP, Vos M, Van Meensel S, Morais VA, De Strooper B, Verstreken P.

PLoS Genet. 2012 Jan;8(1):e1002456. doi: 10.1371/journal.pgen.1002456. Epub 2012 Jan 5.

PMID:
22242018
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The loss of PGAM5 suppresses the mitochondrial degeneration caused by inactivation of PINK1 in Drosophila.

Imai Y, Kanao T, Sawada T, Kobayashi Y, Moriwaki Y, Ishida Y, Takeda K, Ichijo H, Lu B, Takahashi R.

PLoS Genet. 2010 Dec 2;6(12):e1001229. doi: 10.1371/journal.pgen.1001229.

PMID:
21151955
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Olfaction in Parkinson's disease and related disorders.

Doty RL.

Neurobiol Dis. 2012 Jun;46(3):527-52. doi: 10.1016/j.nbd.2011.10.026. Epub 2011 Dec 20. Review.

PMID:
22192366
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Pink1 suppresses alpha-synuclein-induced phenotypes in a Drosophila model of Parkinson's disease.

Todd AM, Staveley BE.

Genome. 2008 Dec;51(12):1040-6. doi: 10.1139/G08-085.

PMID:
19088817
[PubMed - indexed for MEDLINE]
18.

Glutathione S-transferase omega suppresses the defective phenotypes caused by PINK1 loss-of-function in Drosophila.

Kim K, Yim J.

Biochem Biophys Res Commun. 2013 Aug 9;437(4):615-9. doi: 10.1016/j.bbrc.2013.07.011. Epub 2013 Jul 15.

PMID:
23867819
[PubMed - indexed for MEDLINE]
19.

Olfactory dysfunction in LRRK2 G2019S mutation carriers.

Saunders-Pullman R, Stanley K, Wang C, San Luciano M, Shanker V, Hunt A, Severt L, Raymond D, Ozelius LJ, Lipton RB, Bressman SB.

Neurology. 2011 Jul 26;77(4):319-24. doi: 10.1212/WNL.0b013e318227041c. Epub 2011 Jul 13.

PMID:
21753159
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Reduction of protein translation and activation of autophagy protect against PINK1 pathogenesis in Drosophila melanogaster.

Liu S, Lu B.

PLoS Genet. 2010 Dec 9;6(12):e1001237. doi: 10.1371/journal.pgen.1001237.

PMID:
21151574
[PubMed - indexed for MEDLINE]
Free PMC Article
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