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Results: 1 to 20 of 103

1.

Rescue of behavioral and EEG deficits in male and female Mecp2-deficient mice by delayed Mecp2 gene reactivation.

Lang M, Wither RG, Colic S, Wu C, Monnier PP, Bardakjian BL, Zhang L, Eubanks JH.

Hum Mol Genet. 2014 Jan 15;23(2):303-18. doi: 10.1093/hmg/ddt421. Epub 2013 Sep 5.

PMID:
24009314
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Selective preservation of MeCP2 in catecholaminergic cells is sufficient to improve the behavioral phenotype of male and female Mecp2-deficient mice.

Lang M, Wither RG, Brotchie JM, Wu C, Zhang L, Eubanks JH.

Hum Mol Genet. 2013 Jan 15;22(2):358-71. doi: 10.1093/hmg/dds433. Epub 2012 Oct 16.

PMID:
23077217
[PubMed - indexed for MEDLINE]
Free Article
3.

Alterations of cortical and hippocampal EEG activity in MeCP2-deficient mice.

D'Cruz JA, Wu C, Zahid T, El-Hayek Y, Zhang L, Eubanks JH.

Neurobiol Dis. 2010 Apr;38(1):8-16. doi: 10.1016/j.nbd.2009.12.018. Epub 2010 Jan 4.

PMID:
20045053
[PubMed - indexed for MEDLINE]
4.

Targeted delivery of an Mecp2 transgene to forebrain neurons improves the behavior of female Mecp2-deficient mice.

Jugloff DG, Vandamme K, Logan R, Visanji NP, Brotchie JM, Eubanks JH.

Hum Mol Genet. 2008 May 15;17(10):1386-96. doi: 10.1093/hmg/ddn026. Epub 2008 Jan 25.

PMID:
18223199
[PubMed - indexed for MEDLINE]
Free Article
5.

Daily rhythmic behaviors and thermoregulatory patterns are disrupted in adult female MeCP2-deficient mice.

Wither RG, Colic S, Wu C, Bardakjian BL, Zhang L, Eubanks JH.

PLoS One. 2012;7(4):e35396. doi: 10.1371/journal.pone.0035396. Epub 2012 Apr 16.

PMID:
22523589
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

MeCP2 R168X male and female mutant mice exhibit Rett-like behavioral deficits.

Schaevitz LR, Gómez NB, Zhen DP, Berger-Sweeney JE.

Genes Brain Behav. 2013 Oct;12(7):732-40. doi: 10.1111/gbb.12070. Epub 2013 Aug 26.

PMID:
24283265
[PubMed - indexed for MEDLINE]
7.

Dysfunction in GABA signalling mediates autism-like stereotypies and Rett syndrome phenotypes.

Chao HT, Chen H, Samaco RC, Xue M, Chahrour M, Yoo J, Neul JL, Gong S, Lu HC, Heintz N, Ekker M, Rubenstein JL, Noebels JL, Rosenmund C, Zoghbi HY.

Nature. 2010 Nov 11;468(7321):263-9. doi: 10.1038/nature09582.

PMID:
21068835
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Behavioral and anatomical abnormalities in Mecp2 mutant mice: a model for Rett syndrome.

Stearns NA, Schaevitz LR, Bowling H, Nag N, Berger UV, Berger-Sweeney J.

Neuroscience. 2007 May 25;146(3):907-21. Epub 2007 Mar 23.

PMID:
17383101
[PubMed - indexed for MEDLINE]
9.

Regional MeCP2 expression levels in the female MeCP2-deficient mouse brain correlate with specific behavioral impairments.

Wither RG, Lang M, Zhang L, Eubanks JH.

Exp Neurol. 2013 Jan;239:49-59. doi: 10.1016/j.expneurol.2012.09.005. Epub 2012 Sep 26.

PMID:
23022455
[PubMed - indexed for MEDLINE]
10.

A partial loss of function allele of methyl-CpG-binding protein 2 predicts a human neurodevelopmental syndrome.

Samaco RC, Fryer JD, Ren J, Fyffe S, Chao HT, Sun Y, Greer JJ, Zoghbi HY, Neul JL.

Hum Mol Genet. 2008 Jun 15;17(12):1718-27. doi: 10.1093/hmg/ddn062. Epub 2008 Mar 4.

PMID:
18321864
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Reversibility of functional deficits in experimental models of Rett syndrome.

Cobb S, Guy J, Bird A.

Biochem Soc Trans. 2010 Apr;38(2):498-506. doi: 10.1042/BST0380498. Review.

PMID:
20298210
[PubMed - indexed for MEDLINE]
12.

Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndrome--Mecp2 gene dosage effects and BDNF expression.

Kondo M, Gray LJ, Pelka GJ, Christodoulou J, Tam PP, Hannan AJ.

Eur J Neurosci. 2008 Jun;27(12):3342-50. doi: 10.1111/j.1460-9568.2008.06305.x. Epub 2008 Jun 14.

PMID:
18557922
[PubMed - indexed for MEDLINE]
13.

Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome.

Moretti P, Levenson JM, Battaglia F, Atkinson R, Teague R, Antalffy B, Armstrong D, Arancio O, Sweatt JD, Zoghbi HY.

J Neurosci. 2006 Jan 4;26(1):319-27.

PMID:
16399702
[PubMed - indexed for MEDLINE]
Free Article
14.

Acetyl-L-carnitine improves behavior and dendritic morphology in a mouse model of Rett syndrome.

Schaevitz LR, Nicolai R, Lopez CM, D'Iddio S, Iannoni E, Berger-Sweeney JE.

PLoS One. 2012;7(12):e51586. doi: 10.1371/journal.pone.0051586. Epub 2012 Dec 5.

PMID:
23227269
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2.

Giacometti E, Luikenhuis S, Beard C, Jaenisch R.

Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1931-6. Epub 2007 Jan 31.

PMID:
17267601
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Cell-specific expression of wild-type MeCP2 in mouse models of Rett syndrome yields insight about pathogenesis.

Alvarez-Saavedra M, Sáez MA, Kang D, Zoghbi HY, Young JI.

Hum Mol Genet. 2007 Oct 1;16(19):2315-25. Epub 2007 Jul 17.

PMID:
17635839
[PubMed - indexed for MEDLINE]
Free Article
17.

Morphological and functional reversal of phenotypes in a mouse model of Rett syndrome.

Robinson L, Guy J, McKay L, Brockett E, Spike RC, Selfridge J, De Sousa D, Merusi C, Riedel G, Bird A, Cobb SR.

Brain. 2012 Sep;135(Pt 9):2699-710. doi: 10.1093/brain/aws096. Epub 2012 Apr 23.

PMID:
22525157
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Separate respiratory phenotypes in methyl-CpG-binding protein 2 (Mecp2) deficient mice.

Bissonnette JM, Knopp SJ.

Pediatr Res. 2006 Apr;59(4 Pt 1):513-8.

PMID:
16549521
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Low frequency-modulated high frequency oscillations in seizure-like events recorded from in-vivo MeCP2-deficient mice.

Colic S, Lang M, Wither RG, Eubanks JH, Liang Z, Bardakjian BL.

Conf Proc IEEE Eng Med Biol Soc. 2013;2013:985-8. doi: 10.1109/EMBC.2013.6609668.

PMID:
24109855
[PubMed - indexed for MEDLINE]
20.

Early environmental enrichment moderates the behavioral and synaptic phenotype of MeCP2 null mice.

Lonetti G, Angelucci A, Morando L, Boggio EM, Giustetto M, Pizzorusso T.

Biol Psychiatry. 2010 Apr 1;67(7):657-65. doi: 10.1016/j.biopsych.2009.12.022. Epub 2010 Feb 20.

PMID:
20172507
[PubMed - indexed for MEDLINE]

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