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Results: 1 to 20 of 122

1.

Lymphocyte cytosolic protein 1 is a chronic lymphocytic leukemia membrane-associated antigen critical to niche homing.

Dubovsky JA, Chappell DL, Harrington BK, Agrawal K, Andritsos LA, Flynn JM, Jones JA, Paulaitis ME, Bolon B, Johnson AJ, Byrd JC, Muthusamy N.

Blood. 2013 Nov 7;122(19):3308-16. doi: 10.1182/blood-2013-05-504597. Epub 2013 Sep 5.

PMID:
24009233
[PubMed - indexed for MEDLINE]
2.

Identifying CLL antigens for future combinational therapy.

Ramsay AG.

Blood. 2013 Nov 7;122(19):3241-2. doi: 10.1182/blood-2013-09-526376. No abstract available.

PMID:
24203924
[PubMed - indexed for MEDLINE]
3.

Elucidating the CXCL12/CXCR4 signaling network in chronic lymphocytic leukemia through phosphoproteomics analysis.

O'Hayre M, Salanga CL, Kipps TJ, Messmer D, Dorrestein PC, Handel TM.

PLoS One. 2010 Jul 22;5(7):e11716. doi: 10.1371/journal.pone.0011716.

PMID:
20661426
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia.

Buchner M, Baer C, Prinz G, Dierks C, Burger M, Zenz T, Stilgenbauer S, Jumaa H, Veelken H, Zirlik K.

Blood. 2010 Jun 3;115(22):4497-506. doi: 10.1182/blood-2009-07-233692. Epub 2010 Mar 24.

PMID:
20335218
[PubMed - indexed for MEDLINE]
Free Article
5.

B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406.

Quiroga MP, Balakrishnan K, Kurtova AV, Sivina M, Keating MJ, Wierda WG, Gandhi V, Burger JA.

Blood. 2009 Jul 30;114(5):1029-37. doi: 10.1182/blood-2009-03-212837. Epub 2009 Jun 2.

PMID:
19491390
[PubMed - indexed for MEDLINE]
Free Article
6.

The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells.

Longo PG, Laurenti L, Gobessi S, Sica S, Leone G, Efremov DG.

Blood. 2008 Jan 15;111(2):846-55. Epub 2007 Oct 10.

PMID:
17928528
[PubMed - indexed for MEDLINE]
Free Article
7.

Analysis of migratory and prosurvival pathways induced by the homeostatic chemokines CCL19 and CCL21 in B-cell chronic lymphocytic leukemia.

Cuesta-Mateos C, López-Giral S, Alfonso-Pérez M, de Soria VG, Loscertales J, Guasch-Vidal S, Beltrán AE, Zapata JM, Muñoz-Calleja C.

Exp Hematol. 2010 Sep;38(9):756-64, 764.e1-4. doi: 10.1016/j.exphem.2010.05.003. Epub 2010 May 19.

PMID:
20488224
[PubMed - indexed for MEDLINE]
8.

Targeting the microenvironment in chronic lymphocytic leukemia is changing the therapeutic landscape.

Burger JA.

Curr Opin Oncol. 2012 Nov;24(6):643-9. doi: 10.1097/CCO.0b013e3283589950. Review.

PMID:
22960555
[PubMed - indexed for MEDLINE]
9.

BCR signaling in chronic lymphocytic leukemia and related inhibitors currently in clinical studies.

Robak T, Robak P.

Int Rev Immunol. 2013 Aug;32(4):358-76. doi: 10.3109/08830185.2013.786711. Epub 2013 Apr 25. Review.

PMID:
23617253
[PubMed - indexed for MEDLINE]
10.

CD38 increases CXCL12-mediated signals and homing of chronic lymphocytic leukemia cells.

Vaisitti T, Aydin S, Rossi D, Cottino F, Bergui L, D'Arena G, Bonello L, Horenstein AL, Brennan P, Pepper C, Gaidano G, Malavasi F, Deaglio S.

Leukemia. 2010 May;24(5):958-69. doi: 10.1038/leu.2010.36. Epub 2010 Mar 11.

PMID:
20220774
[PubMed - indexed for MEDLINE]
11.

Tiam1/Rac1 signals contribute to the proliferation and chemoresistance, but not motility, of chronic lymphocytic leukemia cells.

Hofbauer SW, Krenn PW, Ganghammer S, Asslaber D, Pichler U, Oberascher K, Henschler R, Wallner M, Kerschbaum H, Greil R, Hartmann TN.

Blood. 2014 Apr 3;123(14):2181-8. doi: 10.1182/blood-2013-08-523563. Epub 2014 Feb 5.

PMID:
24501217
[PubMed - indexed for MEDLINE]
12.

Bruton tyrosine kinase represents a promising therapeutic target for treatment of chronic lymphocytic leukemia and is effectively targeted by PCI-32765.

Herman SE, Gordon AL, Hertlein E, Ramanunni A, Zhang X, Jaglowski S, Flynn J, Jones J, Blum KA, Buggy JJ, Hamdy A, Johnson AJ, Byrd JC.

Blood. 2011 Jun 9;117(23):6287-96. doi: 10.1182/blood-2011-01-328484. Epub 2011 Mar 21.

PMID:
21422473
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia.

Chen L, Widhopf G, Huynh L, Rassenti L, Rai KR, Weiss A, Kipps TJ.

Blood. 2002 Dec 15;100(13):4609-14. Epub 2002 Aug 8.

PMID:
12393534
[PubMed - indexed for MEDLINE]
Free Article
14.

Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL).

Woyach JA, Bojnik E, Ruppert AS, Stefanovski MR, Goettl VM, Smucker KA, Smith LL, Dubovsky JA, Towns WH, MacMurray J, Harrington BK, Davis ME, Gobessi S, Laurenti L, Chang BY, Buggy JJ, Efremov DG, Byrd JC, Johnson AJ.

Blood. 2014 Feb 20;123(8):1207-13. doi: 10.1182/blood-2013-07-515361. Epub 2013 Dec 5.

PMID:
24311722
[PubMed - indexed for MEDLINE]
15.

B cell receptor signaling in chronic lymphocytic leukemia.

Burger JA, Chiorazzi N.

Trends Immunol. 2013 Dec;34(12):592-601. doi: 10.1016/j.it.2013.07.002. Epub 2013 Aug 5. Review.

PMID:
23928062
[PubMed - indexed for MEDLINE]
16.

HS1 has a central role in the trafficking and homing of leukemic B cells.

Scielzo C, Bertilaccio MT, Simonetti G, Dagklis A, ten Hacken E, Fazi C, Muzio M, Caiolfa V, Kitamura D, Restuccia U, Bachi A, Rocchi M, Ponzoni M, Ghia P, Caligaris-Cappio F.

Blood. 2010 Nov 4;116(18):3537-46. doi: 10.1182/blood-2009-12-258814. Epub 2010 Jun 8.

PMID:
20530793
[PubMed - indexed for MEDLINE]
Free Article
17.

Modeling tumor-host interactions of chronic lymphocytic leukemia in xenografted mice to study tumor biology and evaluate targeted therapy.

Herman SE, Sun X, McAuley EM, Hsieh MM, Pittaluga S, Raffeld M, Liu D, Keyvanfar K, Chapman CM, Chen J, Buggy JJ, Aue G, Tisdale JF, Pérez-Galán P, Wiestner A.

Leukemia. 2013 Dec;27(12):2311-21. doi: 10.1038/leu.2013.131. Epub 2013 Apr 26.

PMID:
23619564
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A novel adoptive transfer model of chronic lymphocytic leukemia suggests a key role for T lymphocytes in the disease.

Bagnara D, Kaufman MS, Calissano C, Marsilio S, Patten PE, Simone R, Chum P, Yan XJ, Allen SL, Kolitz JE, Baskar S, Rader C, Mellstedt H, Rabbani H, Lee A, Gregersen PK, Rai KR, Chiorazzi N.

Blood. 2011 May 19;117(20):5463-72. doi: 10.1182/blood-2010-12-324210. Epub 2011 Mar 8.

PMID:
21385850
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

RhoH is critical for cell-microenvironment interactions in chronic lymphocytic leukemia in mice and humans.

Troeger A, Johnson AJ, Wood J, Blum WG, Andritsos LA, Byrd JC, Williams DA.

Blood. 2012 May 17;119(20):4708-18. doi: 10.1182/blood-2011-12-395939. Epub 2012 Apr 3.

PMID:
22474251
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Chronic lymphocytic leukemia B cells contain anomalous Lyn tyrosine kinase, a putative contribution to defective apoptosis.

Contri A, Brunati AM, Trentin L, Cabrelle A, Miorin M, Cesaro L, Pinna LA, Zambello R, Semenzato G, Donella-Deana A.

J Clin Invest. 2005 Feb;115(2):369-78.

PMID:
15650771
[PubMed - indexed for MEDLINE]
Free PMC Article

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