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Items: 1 to 20 of 122

1.

Involvement of A20 in the molecular switch that activates the non-canonical NF-кB pathway.

Yamaguchi N, Oyama M, Kozuka-Hata H, Inoue J.

Sci Rep. 2013;3:2568. doi: 10.1038/srep02568.

2.

TACI induces cIAP1-mediated ubiquitination of NIK by TRAF2 and TANK to limit non-canonical NF-kappaB signaling.

Kanno Y, Sakurai D, Hase H, Kojima H, Kobata T.

J Recept Signal Transduct Res. 2010 Apr;30(2):121-32. doi: 10.3109/10799891003634509.

PMID:
20184394
3.

Nonredundant and complementary functions of TRAF2 and TRAF3 in a ubiquitination cascade that activates NIK-dependent alternative NF-kappaB signaling.

Vallabhapurapu S, Matsuzawa A, Zhang W, Tseng PH, Keats JJ, Wang H, Vignali DA, Bergsagel PL, Karin M.

Nat Immunol. 2008 Dec;9(12):1364-70. doi: 10.1038/ni.1678. Epub 2008 Nov 9.

4.
5.

Inhibition of NF-kappaB signaling by A20 through disruption of ubiquitin enzyme complexes.

Shembade N, Ma A, Harhaj EW.

Science. 2010 Feb 26;327(5969):1135-9. doi: 10.1126/science.1182364.

6.

Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-κB regulation.

Tokunaga F, Nishimasu H, Ishitani R, Goto E, Noguchi T, Mio K, Kamei K, Ma A, Iwai K, Nureki O.

EMBO J. 2012 Oct 3;31(19):3856-70. doi: 10.1038/emboj.2012.241. Epub 2012 Aug 28.

7.

A20-mediated negative regulation of canonical NF-κB signaling pathway.

Pujari R, Hunte R, Khan WN, Shembade N.

Immunol Res. 2013 Dec;57(1-3):166-71. doi: 10.1007/s12026-013-8463-2. Review.

PMID:
24242761
8.

Novel anti-apoptotic mechanism of A20 through targeting ASK1 to suppress TNF-induced JNK activation.

Won M, Park KA, Byun HS, Sohn KC, Kim YR, Jeon J, Hong JH, Park J, Seok JH, Kim JM, Yoon WH, Jang IS, Shen HM, Liu ZG, Hur GM.

Cell Death Differ. 2010 Dec;17(12):1830-41. doi: 10.1038/cdd.2010.47. Epub 2010 May 7.

9.

XEDAR activates the non-canonical NF-κB pathway.

Verhelst K, Gardam S, Borghi A, Kreike M, Carpentier I, Beyaert R.

Biochem Biophys Res Commun. 2015 Sep 18;465(2):275-80. doi: 10.1016/j.bbrc.2015.08.019. Epub 2015 Aug 8.

PMID:
26260321
10.

Roles of TRAF2 and TRAF3 in Epstein-Barr virus latent membrane protein 1-induced alternative NF-kappaB activation.

Song YJ, Kang MS.

Virus Genes. 2010 Oct;41(2):174-80. doi: 10.1007/s11262-010-0505-4. Epub 2010 Jun 29.

PMID:
20585848
11.

The seventh zinc finger motif of A20 is required for the suppression of TNF-α-induced apoptosis.

Yamaguchi N, Yamaguchi N.

FEBS Lett. 2015 May 22;589(12):1369-75. doi: 10.1016/j.febslet.2015.04.022. Epub 2015 Apr 22.

PMID:
25911380
12.

Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.

Zarnegar BJ, Wang Y, Mahoney DJ, Dempsey PW, Cheung HH, He J, Shiba T, Yang X, Yeh WC, Mak TW, Korneluk RG, Cheng G.

Nat Immunol. 2008 Dec;9(12):1371-8. doi: 10.1038/ni.1676. Epub 2008 Nov 9.

13.

Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-κB-inducing kinase while activating both canonical and alternative nuclear factor-κB pathways.

Pham LV, Fu L, Tamayo AT, Bueso-Ramos C, Drakos E, Vega F, Medeiros LJ, Ford RJ.

Blood. 2011 Jan 6;117(1):200-10. doi: 10.1182/blood-2010-06-290437. Epub 2010 Oct 1.

14.

An atypical E3 ligase zinc finger protein 91 stabilizes and activates NF-kappaB-inducing kinase via Lys63-linked ubiquitination.

Jin X, Jin HR, Jung HS, Lee SJ, Lee JH, Lee JJ.

J Biol Chem. 2010 Oct 1;285(40):30539-47. doi: 10.1074/jbc.M110.129551. Epub 2010 Aug 3.

15.

A20 inhibits LUBAC-mediated NF-κB activation by binding linear polyubiquitin chains via its zinc finger 7.

Verhelst K, Carpentier I, Kreike M, Meloni L, Verstrepen L, Kensche T, Dikic I, Beyaert R.

EMBO J. 2012 Oct 3;31(19):3845-55. doi: 10.1038/emboj.2012.240. Epub 2012 Aug 28.

16.

ABINs: A20 binding inhibitors of NF-kappa B and apoptosis signaling.

Verstrepen L, Carpentier I, Verhelst K, Beyaert R.

Biochem Pharmacol. 2009 Jul 15;78(2):105-14. doi: 10.1016/j.bcp.2009.02.009. Epub 2009 Feb 27. Review.

PMID:
19464428
17.

A20 negatively regulates T cell receptor signaling to NF-kappaB by cleaving Malt1 ubiquitin chains.

Düwel M, Welteke V, Oeckinghaus A, Baens M, Kloo B, Ferch U, Darnay BG, Ruland J, Marynen P, Krappmann D.

J Immunol. 2009 Jun 15;182(12):7718-28. doi: 10.4049/jimmunol.0803313.

18.

Non-canonical NF-κB signaling activation and regulation: principles and perspectives.

Razani B, Reichardt AD, Cheng G.

Immunol Rev. 2011 Nov;244(1):44-54. doi: 10.1111/j.1600-065X.2011.01059.x. Review.

PMID:
22017430
19.

APPL1 regulates basal NF-κB activity by stabilizing NIK.

Hupalowska A, Pyrzynska B, Miaczynska M.

J Cell Sci. 2012 Sep 1;125(Pt 17):4090-102. doi: 10.1242/jcs.105171. Epub 2012 Jun 8.

20.

TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis.

Vince JE, Pantaki D, Feltham R, Mace PD, Cordier SM, Schmukle AC, Davidson AJ, Callus BA, Wong WW, Gentle IE, Carter H, Lee EF, Walczak H, Day CL, Vaux DL, Silke J.

J Biol Chem. 2009 Dec 18;284(51):35906-15. doi: 10.1074/jbc.M109.072256. Epub .

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