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Results: 1 to 20 of 139

1.

Stimulation of sigma receptors with afobazole blocks activation of microglia and reduces toxicity caused by amyloid-β25-35.

Behensky AA, Yasny IE, Shuster AM, Seredenin SB, Petrov AV, Cuevas J.

J Pharmacol Exp Ther. 2013 Nov;347(2):458-67. doi: 10.1124/jpet.113.208348. Epub 2013 Sep 4.

PMID:
24006337
[PubMed - indexed for MEDLINE]
Free Article
2.

Afobazole activation of σ-1 receptors modulates neuronal responses to amyloid-β25-35.

Behensky AA, Yasny IE, Shuster AM, Seredenin SB, Petrov AV, Cuevas J.

J Pharmacol Exp Ther. 2013 Nov;347(2):468-77. doi: 10.1124/jpet.113.208330. Epub 2013 Sep 4.

PMID:
24006338
[PubMed - indexed for MEDLINE]
Free Article
3.

Afobazole modulates microglial function via activation of both sigma-1 and sigma-2 receptors.

Cuevas J, Rodriguez A, Behensky A, Katnik C.

J Pharmacol Exp Ther. 2011 Oct;339(1):161-72. doi: 10.1124/jpet.111.182816. Epub 2011 Jun 29.

PMID:
21715561
[PubMed - indexed for MEDLINE]
Free Article
4.

Afobazole modulates neuronal response to ischemia and acidosis via activation of sigma-1 receptors.

Cuevas J, Behensky A, Deng W, Katnik C.

J Pharmacol Exp Ther. 2011 Oct;339(1):152-60. doi: 10.1124/jpet.111.182774. Epub 2011 Jun 29.

PMID:
21715562
[PubMed - indexed for MEDLINE]
Free Article
5.

Methyl 3,4-dihydroxybenzoate protects primary cortical neurons against Aβ₂₅₋₃₅-induced neurotoxicity through mitochondria pathway.

Zhou XW, Zhang Z, Su CF, Lv RH, Zhou X, Cai L, Wang CY, Yan L, Zhang W, Luo HM.

J Neurosci Res. 2013 Sep;91(9):1215-25. doi: 10.1002/jnr.23235. Epub 2013 Jul 3.

PMID:
23861072
[PubMed - indexed for MEDLINE]
6.

Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.

Dhawan G, Combs CK.

J Neuroinflammation. 2012 Jul 2;9:117. doi: 10.1186/1742-2094-9-117.

PMID:
22673542
[PubMed - indexed for MEDLINE]
Free PMC Article
7.
8.

A multifunctional peptide rescues memory deficits in Alzheimer's disease transgenic mice by inhibiting Aβ42-induced cytotoxicity and increasing microglial phagocytosis.

Xue D, Zhao M, Wang YJ, Wang L, Yang Y, Wang SW, Zhang R, Zhao Y, Liu RT.

Neurobiol Dis. 2012 Jun;46(3):701-9. doi: 10.1016/j.nbd.2012.03.013. Epub 2012 Mar 9.

PMID:
22426388
[PubMed - indexed for MEDLINE]
9.

Attenuation of Aβ25-35-induced parallel autophagic and apoptotic cell death by gypenoside XVII through the estrogen receptor-dependent activation of Nrf2/ARE pathways.

Meng X, Wang M, Sun G, Ye J, Zhou Y, Dong X, Wang T, Lu S, Sun X.

Toxicol Appl Pharmacol. 2014 Aug 15;279(1):63-75. doi: 10.1016/j.taap.2014.03.026. Epub 2014 Apr 12.

PMID:
24726523
[PubMed - indexed for MEDLINE]
10.

Prevention of Alzheimer's disease pathology by cannabinoids: neuroprotection mediated by blockade of microglial activation.

Ramírez BG, Blázquez C, Gómez del Pulgar T, Guzmán M, de Ceballos ML.

J Neurosci. 2005 Feb 23;25(8):1904-13.

PMID:
15728830
[PubMed - indexed for MEDLINE]
Free Article
11.

Activation of SIRT1 by curcumin blocks the neurotoxicity of amyloid-β25-35 in rat cortical neurons.

Sun Q, Jia N, Wang W, Jin H, Xu J, Hu H.

Biochem Biophys Res Commun. 2014 May 23;448(1):89-94. doi: 10.1016/j.bbrc.2014.04.066. Epub 2014 Apr 19.

PMID:
24755072
[PubMed - indexed for MEDLINE]
12.

Knockout of Toll-like receptor 2 attenuates Aβ25-35-induced neurotoxicity in organotypic hippocampal slice cultures.

Suh EC, Jung YJ, Kim YA, Park EM, Lee SJ, Lee KE.

Neurochem Int. 2013 Dec;63(8):818-25. doi: 10.1016/j.neuint.2013.10.007. Epub 2013 Oct 23.

PMID:
24161618
[PubMed - indexed for MEDLINE]
Free Article
13.

Neuroprotective effects of sigma-1 receptor agonists against beta-amyloid-induced toxicity.

Marrazzo A, Caraci F, Salinaro ET, Su TP, Copani A, Ronsisvalle G.

Neuroreport. 2005 Aug 1;16(11):1223-6.

PMID:
16012353
[PubMed - indexed for MEDLINE]
14.

An effector-reduced anti-β-amyloid (Aβ) antibody with unique aβ binding properties promotes neuroprotection and glial engulfment of Aβ.

Adolfsson O, Pihlgren M, Toni N, Varisco Y, Buccarello AL, Antoniello K, Lohmann S, Piorkowska K, Gafner V, Atwal JK, Maloney J, Chen M, Gogineni A, Weimer RM, Mortensen DL, Friesenhahn M, Ho C, Paul R, Pfeifer A, Muhs A, Watts RJ.

J Neurosci. 2012 Jul 11;32(28):9677-89. doi: 10.1523/JNEUROSCI.4742-11.2012.

PMID:
22787053
[PubMed - indexed for MEDLINE]
Free Article
15.
16.

Sinomenine inhibits microglial activation by Aβ and confers neuroprotection.

Shukla SM, Sharma SK.

J Neuroinflammation. 2011 Sep 14;8:117. doi: 10.1186/1742-2094-8-117.

PMID:
21917137
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The Ginkgo biloba extract (EGb 761) protects hippocampal neurons against cell death induced by beta-amyloid.

Bastianetto S, Ramassamy C, Doré S, Christen Y, Poirier J, Quirion R.

Eur J Neurosci. 2000 Jun;12(6):1882-90.

PMID:
10886329
[PubMed - indexed for MEDLINE]
18.

System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40.

Qin S, Colin C, Hinners I, Gervais A, Cheret C, Mallat M.

J Neurosci. 2006 Mar 22;26(12):3345-56.

PMID:
16554485
[PubMed - indexed for MEDLINE]
Free Article
19.

Nucleotides released from Aβ₁₋₄₂ -treated microglial cells increase cell migration and Aβ₁₋₄₂ uptake through P2Y₂ receptor activation.

Kim HJ, Ajit D, Peterson TS, Wang Y, Camden JM, Gibson Wood W, Sun GY, Erb L, Petris M, Weisman GA.

J Neurochem. 2012 Apr;121(2):228-38. doi: 10.1111/j.1471-4159.2012.07700.x. Epub 2012 Mar 14.

PMID:
22353164
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Activation of microglial group III metabotropic glutamate receptors protects neurons against microglial neurotoxicity.

Taylor DL, Diemel LT, Pocock JM.

J Neurosci. 2003 Mar 15;23(6):2150-60.

PMID:
12657674
[PubMed - indexed for MEDLINE]
Free Article

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