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Results: 1 to 20 of 110

1.

Extracellular Ca(2+) and Mg(2+) modulate aminoglycoside blockade of mechanotransducer channel-mediated Ca(2+) entry in zebrafish hair cells: an in vivo study with the SIET.

Lin LY, Pang W, Chuang WM, Hung GY, Lin YH, Horng JL.

Am J Physiol Cell Physiol. 2013 Nov 15;305(10):C1060-8. doi: 10.1152/ajpcell.00077.2013. Epub 2013 Sep 4.

PMID:
24005042
[PubMed - indexed for MEDLINE]
2.

Functional hair cell mechanotransducer channels are required for aminoglycoside ototoxicity.

Alharazneh A, Luk L, Huth M, Monfared A, Steyger PS, Cheng AG, Ricci AJ.

PLoS One. 2011;6(7):e22347. doi: 10.1371/journal.pone.0022347. Epub 2011 Jul 26.

PMID:
21818312
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Extracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral line.

Coffin AB, Reinhart KE, Owens KN, Raible DW, Rubel EW.

Hear Res. 2009 Jul;253(1-2):42-51. doi: 10.1016/j.heares.2009.03.004. Epub 2009 Mar 12.

PMID:
19285547
[PubMed - indexed for MEDLINE]
4.

Aminoglycoside antibiotics impair calcium entry but not viability and motility in isolated cochlear outer hair cells.

Dulon D, Zajic G, Aran JM, Schacht J.

J Neurosci Res. 1989 Oct;24(2):338-46.

PMID:
2585554
[PubMed - indexed for MEDLINE]
5.

Trafficking of systemic fluorescent gentamicin into the cochlea and hair cells.

Wang Q, Steyger PS.

J Assoc Res Otolaryngol. 2009 Jun;10(2):205-19. doi: 10.1007/s10162-009-0160-4. Epub 2009 Mar 3.

PMID:
19255807
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Loss of Slc4a1b chloride/bicarbonate exchanger function protects mechanosensory hair cells from aminoglycoside damage in the zebrafish mutant persephone.

Hailey DW, Roberts B, Owens KN, Stewart AK, Linbo T, Pujol R, Alper SL, Rubel EW, Raible DW.

PLoS Genet. 2012;8(10):e1002971. doi: 10.1371/journal.pgen.1002971. Epub 2012 Oct 11.

PMID:
23071446
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Screen of FDA-approved drug library reveals compounds that protect hair cells from aminoglycosides and cisplatin.

Vlasits AL, Simon JA, Raible DW, Rubel EW, Owens KN.

Hear Res. 2012 Dec;294(1-2):153-65. doi: 10.1016/j.heares.2012.08.002. Epub 2012 Aug 31.

PMID:
22967486
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Fucoidan promotes mechanosensory hair cell regeneration following amino glycoside-induced cell death.

Moon IS, So JH, Jung YM, Lee WS, Kim EY, Choi JH, Kim CH, Choi JY.

Hear Res. 2011 Dec;282(1-2):236-42. doi: 10.1016/j.heares.2011.07.007. Epub 2011 Jul 23.

PMID:
21810458
[PubMed - indexed for MEDLINE]
9.

FM1-43 dye behaves as a permeant blocker of the hair-cell mechanotransducer channel.

Gale JE, Marcotti W, Kennedy HJ, Kros CJ, Richardson GP.

J Neurosci. 2001 Sep 15;21(18):7013-25.

PMID:
11549711
[PubMed - indexed for MEDLINE]
Free Article
10.

Bax, Bcl2, and p53 differentially regulate neomycin- and gentamicin-induced hair cell death in the zebrafish lateral line.

Coffin AB, Rubel EW, Raible DW.

J Assoc Res Otolaryngol. 2013 Oct;14(5):645-59. doi: 10.1007/s10162-013-0404-1. Epub 2013 Jul 3.

PMID:
23821348
[PubMed - indexed for MEDLINE]
11.

Cochlear cultures as a model system for studying aminoglycoside induced ototoxicity.

Richardson GP, Russell IJ.

Hear Res. 1991 Jun;53(2):293-311.

PMID:
1880082
[PubMed - indexed for MEDLINE]
12.

Profiling drug-induced cell death pathways in the zebrafish lateral line.

Coffin AB, Williamson KL, Mamiya A, Raible DW, Rubel EW.

Apoptosis. 2013 Apr;18(4):393-408. doi: 10.1007/s10495-013-0816-8.

PMID:
23413197
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Aminoglycoside-induced hair cell death of inner ear organs causes functional deficits in adult zebrafish (Danio rerio).

Uribe PM, Sun H, Wang K, Asuncion JD, Wang Q, Chen CW, Steyger PS, Smith ME, Matsui JI.

PLoS One. 2013;8(3):e58755. doi: 10.1371/journal.pone.0058755. Epub 2013 Mar 22.

PMID:
23533589
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Response of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways.

Owens KN, Coffin AB, Hong LS, Bennett KO, Rubel EW, Raible DW.

Hear Res. 2009 Jul;253(1-2):32-41. doi: 10.1016/j.heares.2009.03.001. Epub 2009 Mar 11.

PMID:
19285126
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Inhibition of K+ currents in type I vestibular hair cells by gentamicin and neomycin.

Mann SE, Johnson M, Meredith FL, Rennie KJ.

Audiol Neurootol. 2013;18(5):317-26. doi: 10.1159/000354056. Epub 2013 Sep 19.

PMID:
24051519
[PubMed - indexed for MEDLINE]
16.

Gentamicin is ototoxic to all hair cells in the fish lateral line system.

Van Trump WJ, Coombs S, Duncan K, McHenry MJ.

Hear Res. 2010 Mar;261(1-2):42-50. doi: 10.1016/j.heares.2010.01.001. Epub 2010 Jan 7.

PMID:
20060460
[PubMed - indexed for MEDLINE]
17.

[Zebrafish model for the study on drug ototoxicity of aminoglycoside antibiotics].

Zhao Z, Tong JW, Zhang JP, You XF, Jiang JD, Hu CQ.

Yao Xue Xue Bao. 2011 Aug;46(8):928-35. Chinese.

PMID:
22007517
[PubMed - indexed for MEDLINE]
18.

Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line.

Ma EY, Rubel EW, Raible DW.

J Neurosci. 2008 Feb 27;28(9):2261-73. doi: 10.1523/JNEUROSCI.4372-07.2008.

PMID:
18305259
[PubMed - indexed for MEDLINE]
Free Article
19.

Different uptake of gentamicin through TRPV1 and TRPV4 channels determines cochlear hair cell vulnerability.

Lee JH, Park C, Kim SJ, Kim HJ, Oh GS, Shen A, So HS, Park R.

Exp Mol Med. 2013 Mar 8;45:e12. doi: 10.1038/emm.2013.25.

PMID:
23470714
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Calcium permeation of the turtle hair cell mechanotransducer channel and its relation to the composition of endolymph.

Ricci AJ, Fettiplace R.

J Physiol. 1998 Jan 1;506 ( Pt 1):159-73. Erratum in: J Physiol (Lond) 1998 Mar 15;507(Pt 3):939.

PMID:
9481679
[PubMed - indexed for MEDLINE]
Free PMC Article

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