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Items: 1 to 20 of 164

1.

Epigenetic profiles as defined signatures of xenobiotic exposure.

Thomson JP, Moggs JG, Wolf CR, Meehan RR.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Apr;764-765:3-9. doi: 10.1016/j.mrgentox.2013.08.007. Epub 2013 Aug 31. Review.

PMID:
24001620
2.

Non-genotoxic carcinogen exposure induces defined changes in the 5-hydroxymethylome.

Thomson JP, Lempiäinen H, Hackett JA, Nestor CE, Müller A, Bolognani F, Oakeley EJ, Schübeler D, Terranova R, Reinhardt D, Moggs JG, Meehan RR.

Genome Biol. 2012 Oct 3;13(10):R93. doi: 10.1186/gb-2012-13-10-r93.

3.

Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.

Thomson JP, Hunter JM, Lempiäinen H, Müller A, Terranova R, Moggs JG, Meehan RR.

Nucleic Acids Res. 2013 Jun;41(11):5639-54. doi: 10.1093/nar/gkt232. Epub 2013 Apr 17.

4.

Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain.

Coppieters N, Dieriks BV, Lill C, Faull RL, Curtis MA, Dragunow M.

Neurobiol Aging. 2014 Jun;35(6):1334-44. doi: 10.1016/j.neurobiolaging.2013.11.031. Epub 2013 Dec 4.

PMID:
24387984
5.

Expanding the epigenetic landscape: novel modifications of cytosine in genomic DNA.

Kriaucionis S, Tahiliani M.

Cold Spring Harb Perspect Biol. 2014 Oct 1;6(10):a018630. doi: 10.1101/cshperspect.a018630. Review.

PMID:
25274704
6.

5-Hydroxymethylcytosine: generation, fate, and genomic distribution.

Shen L, Zhang Y.

Curr Opin Cell Biol. 2013 Jun;25(3):289-96. doi: 10.1016/j.ceb.2013.02.017. Epub 2013 Mar 13. Review.

7.

5-Hydroxymethylcytosine and disease.

Wang J, Tang J, Lai M, Zhang H.

Mutat Res Rev Mutat Res. 2014 Oct-Dec;762:167-75. doi: 10.1016/j.mrrev.2014.09.003. Epub 2014 Oct 8. Review.

PMID:
25475423
8.

Studying the epigenome using next generation sequencing.

Ku CS, Naidoo N, Wu M, Soong R.

J Med Genet. 2011 Nov;48(11):721-30. doi: 10.1136/jmedgenet-2011-100242. Epub 2011 Aug 8. Review.

PMID:
21825079
9.

Uncovering the role of 5-hydroxymethylcytosine in the epigenome.

Branco MR, Ficz G, Reik W.

Nat Rev Genet. 2011 Nov 15;13(1):7-13. doi: 10.1038/nrg3080. Review.

PMID:
22083101
10.

Increased 5-hydroxymethylcytosine and decreased 5-methylcytosine are indicators of global epigenetic dysregulation in diffuse intrinsic pontine glioma.

Ahsan S, Raabe EH, Haffner MC, Vaghasia A, Warren KE, Quezado M, Ballester LY, Nazarian J, Eberhart CG, Rodriguez FJ.

Acta Neuropathol Commun. 2014 Jun 3;2:59. doi: 10.1186/2051-5960-2-59.

11.

Nucleic acid modifications with epigenetic significance.

Fu Y, He C.

Curr Opin Chem Biol. 2012 Dec;16(5-6):516-24. doi: 10.1016/j.cbpa.2012.10.002. Epub 2012 Oct 22. Review.

12.

Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers.

Olkhov-Mitsel E, Bapat B.

Cancer Med. 2012 Oct;1(2):237-60. doi: 10.1002/cam4.22. Epub 2012 Sep 14. Review.

13.

Epigenetic regulation of colon cancer and intestinal stem cells.

Hammoud SS, Cairns BR, Jones DA.

Curr Opin Cell Biol. 2013 Apr;25(2):177-83. doi: 10.1016/j.ceb.2013.01.007. Epub 2013 Feb 8. Review.

14.

DNA immunoprecipitation semiconductor sequencing (DIP-SC-seq) as a rapid method to generate genome wide epigenetic signatures.

Thomson JP, Fawkes A, Ottaviano R, Hunter JM, Shukla R, Mjoseng HK, Clark R, Coutts A, Murphy L, Meehan RR.

Sci Rep. 2015 May 14;5:9778. doi: 10.1038/srep09778.

15.

Advances in DNA methylation: 5-hydroxymethylcytosine revisited.

Dahl C, Grønbæk K, Guldberg P.

Clin Chim Acta. 2011 May 12;412(11-12):831-6. doi: 10.1016/j.cca.2011.02.013. Epub 2011 Feb 12. Review.

PMID:
21324307
16.

Dynamics of 5-hydroxymethylcytosine and chromatin marks in Mammalian neurogenesis.

Hahn MA, Qiu R, Wu X, Li AX, Zhang H, Wang J, Jui J, Jin SG, Jiang Y, Pfeifer GP, Lu Q.

Cell Rep. 2013 Feb 21;3(2):291-300. doi: 10.1016/j.celrep.2013.01.011. Epub 2013 Feb 9.

17.

Integrating 5-hydroxymethylcytosine into the epigenomic landscape of human embryonic stem cells.

Szulwach KE, Li X, Li Y, Song CX, Han JW, Kim S, Namburi S, Hermetz K, Kim JJ, Rudd MK, Yoon YS, Ren B, He C, Jin P.

PLoS Genet. 2011 Jun;7(6):e1002154. doi: 10.1371/journal.pgen.1002154. Epub 2011 Jun 23.

18.

Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice.

Lempiäinen H, Müller A, Brasa S, Teo SS, Roloff TC, Morawiec L, Zamurovic N, Vicart A, Funhoff E, Couttet P, Schübeler D, Grenet O, Marlowe J, Moggs J, Terranova R.

PLoS One. 2011 Mar 24;6(3):e18216. doi: 10.1371/journal.pone.0018216.

19.

Introduction to epigenomics and epigenome-wide analysis.

Fazzari MJ, Greally JM.

Methods Mol Biol. 2010;620:243-65. doi: 10.1007/978-1-60761-580-4_7. Review.

PMID:
20652507
20.

Epigenetics and chemical safety - concluding remarks.

Kleinjans J, van Ravenzwaay B.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Apr;764-765:72-3. doi: 10.1016/j.mrgentox.2014.03.003. Epub 2014 Mar 24. No abstract available.

PMID:
24674849
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