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Results: 1 to 20 of 159

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1.

Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health?

Pekkala S, Wiklund PK, Hulmi JJ, Ahtiainen JP, Horttanainen M, Pöllänen E, Mäkelä KA, Kainulainen H, Häkkinen K, Nyman K, Alén M, Herzig KH, Cheng S.

J Physiol. 2013 Nov 1;591(Pt 21):5393-400. doi: 10.1113/jphysiol.2013.263707. Epub 2013 Sep 2.

2.

The effects of acute and chronic exercise on PGC-1α, irisin and browning of subcutaneous adipose tissue in humans.

Norheim F, Langleite TM, Hjorth M, Holen T, Kielland A, Stadheim HK, Gulseth HL, Birkeland KI, Jensen J, Drevon CA.

FEBS J. 2014 Feb;281(3):739-49. doi: 10.1111/febs.12619. Epub 2013 Dec 10.

PMID:
24237962
3.

SMAD3 negatively regulates serum irisin and skeletal muscle FNDC5 and peroxisome proliferator-activated receptor γ coactivator 1-α (PGC-1α) during exercise.

Tiano JP, Springer DA, Rane SG.

J Biol Chem. 2015 Mar 20;290(12):7671-84. doi: 10.1074/jbc.M114.617399. Epub 2015 Feb 3. Erratum in: J Biol Chem. 2015 May 1;290(18):11431.

PMID:
25648888
4.

Irisin and FNDC5: effects of 12-week strength training, and relations to muscle phenotype and body mass composition in untrained women.

Ellefsen S, Vikmoen O, Slettaløkken G, Whist JE, Nygaard H, Hollan I, Rauk I, Vegge G, Strand TA, Raastad T, Rønnestad BR.

Eur J Appl Physiol. 2014 Sep;114(9):1875-88. doi: 10.1007/s00421-014-2922-x. Epub 2014 Jun 7.

PMID:
24906447
5.

Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure.

Lecker SH, Zavin A, Cao P, Arena R, Allsup K, Daniels KM, Joseph J, Schulze PC, Forman DE.

Circ Heart Fail. 2012 Nov;5(6):812-8. doi: 10.1161/CIRCHEARTFAILURE.112.969543. Epub 2012 Sep 20.

6.

FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise.

Huh JY, Panagiotou G, Mougios V, Brinkoetter M, Vamvini MT, Schneider BE, Mantzoros CS.

Metabolism. 2012 Dec;61(12):1725-38. doi: 10.1016/j.metabol.2012.09.002. Epub 2012 Sep 25.

7.

Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs.

Fain JN, Company JM, Booth FW, Laughlin MH, Padilla J, Jenkins NT, Bahouth SW, Sacks HS.

Metabolism. 2013 Oct;62(10):1503-11. doi: 10.1016/j.metabol.2013.05.021. Epub 2013 Jul 5.

8.

Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies.

Kurdiova T, Balaz M, Vician M, Maderova D, Vlcek M, Valkovic L, Srbecky M, Imrich R, Kyselovicova O, Belan V, Jelok I, Wolfrum C, Klimes I, Krssak M, Zemkova E, Gasperikova D, Ukropec J, Ukropcova B.

J Physiol. 2014 Mar 1;592(Pt 5):1091-107. doi: 10.1113/jphysiol.2013.264655. Epub 2013 Dec 2.

9.

Exercise-mimicking treatment fails to increase Fndc5 mRNA & irisin secretion in primary human myotubes.

Kurdiova T, Balaz M, Mayer A, Maderova D, Belan V, Wolfrum C, Ukropec J, Ukropcova B.

Peptides. 2014 Jun;56:1-7. doi: 10.1016/j.peptides.2014.03.003. Epub 2014 Mar 16.

PMID:
24642356
10.

Circulating irisin levels and muscle FNDC5 mRNA expression are independent of IL-15 levels in mice.

Quinn LS, Anderson BG, Conner JD, Wolden-Hanson T.

Endocrine. 2015 Apr 29. [Epub ahead of print]

PMID:
25920499
11.

Irisin is elevated in skeletal muscle and serum of mice immediately after acute exercise.

Brenmoehl J, Albrecht E, Komolka K, Schering L, Langhammer M, Hoeflich A, Maak S.

Int J Biol Sci. 2014 Mar 11;10(3):338-49. doi: 10.7150/ijbs.7972. eCollection 2014.

12.

Truncated splice variant PGC-1α4 is not associated with exercise-induced human muscle hypertrophy.

Lundberg TR, Fernandez-Gonzalo R, Norrbom J, Fischer H, Tesch PA, Gustafsson T.

Acta Physiol (Oxf). 2014 Oct;212(2):142-51. doi: 10.1111/apha.12310. Epub 2014 May 21.

PMID:
24800995
13.

Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance.

Moreno-Navarrete JM, Ortega F, Serrano M, Guerra E, Pardo G, Tinahones F, Ricart W, Fernández-Real JM.

J Clin Endocrinol Metab. 2013 Apr;98(4):E769-78. doi: 10.1210/jc.2012-2749. Epub 2013 Feb 22.

PMID:
23436919
14.

Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats.

Roberts MD, Bayless DS, Company JM, Jenkins NT, Padilla J, Childs TE, Martin JS, Dalbo VJ, Booth FW, Rector RS, Laughlin MH.

Metabolism. 2013 Aug;62(8):1052-6. doi: 10.1016/j.metabol.2013.02.002. Epub 2013 Mar 14.

15.

One session of exercise or endurance training does not influence serum levels of irisin in rats.

Czarkowska-Paczek B, Zendzian-Piotrowska M, Gala K, Sobol M, Paczek L.

J Physiol Pharmacol. 2014 Jun;65(3):449-54.

16.

Thermogenic capacity is antagonistically regulated in classical brown and white subcutaneous fat depots by high fat diet and endurance training in rats: impact on whole-body energy expenditure.

Wu MV, Bikopoulos G, Hung S, Ceddia RB.

J Biol Chem. 2014 Dec 5;289(49):34129-40. doi: 10.1074/jbc.M114.591008. Epub 2014 Oct 25.

PMID:
25344623
17.
18.

Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway.

Wrann CD, White JP, Salogiannnis J, Laznik-Bogoslavski D, Wu J, Ma D, Lin JD, Greenberg ME, Spiegelman BM.

Cell Metab. 2013 Nov 5;18(5):649-59. doi: 10.1016/j.cmet.2013.09.008. Epub 2013 Oct 10.

19.

Striated muscle activator of Rho signalling (STARS) is a PGC-1α/oestrogen-related receptor-α target gene and is upregulated in human skeletal muscle after endurance exercise.

Wallace MA, Hock MB, Hazen BC, Kralli A, Snow RJ, Russell AP.

J Physiol. 2011 Apr 15;589(Pt 8):2027-39. doi: 10.1113/jphysiol.2011.205468. Epub 2011 Feb 21.

20.

Fibronectin type III domain containing 5 expression in skeletal muscle in chronic heart failure-relevance of inflammatory cytokines.

Matsuo Y, Gleitsmann K, Mangner N, Werner S, Fischer T, Bowen TS, Kricke A, Matsumoto Y, Kurabayashi M, Schuler G, Linke A, Adams V.

J Cachexia Sarcopenia Muscle. 2015 Mar;6(1):62-72. doi: 10.1002/jcsm.12006. Epub 2015 Mar 31.

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