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Similar articles for PubMed (Select 23999295)

1.

The structure of XIAP BIR2: understanding the selectivity of the BIR domains.

Lukacs C, Belunis C, Crowther R, Danho W, Gao L, Goggin B, Janson CA, Li S, Remiszewski S, Schutt A, Thakur MK, Singh SK, Swaminathan S, Pandey R, Tyagi R, Gosu R, Kamath AV, Kuglstatter A.

Acta Crystallogr D Biol Crystallogr. 2013 Sep;69(Pt 9):1717-25. doi: 10.1107/S0907444913016284. Epub 2013 Aug 15.

2.

Characterization of an inhibitor of apoptosis protein in Crassostrea gigas clarifies its role in apoptosis and immune defense.

Qu T, Zhang L, Wang W, Huang B, Li Y, Zhu Q, Li L, Zhang G.

Dev Comp Immunol. 2015 Jul;51(1):74-8. doi: 10.1016/j.dci.2015.02.011. Epub 2015 Feb 23.

PMID:
25720977
3.

The discovery of macrocyclic XIAP antagonists from a DNA-programmed chemistry library, and their optimization to give lead compounds with in vivo antitumor activity.

Seigal BA, Connors WH, Fraley A, Borzilleri RM, Carter PH, Emanuel SL, Fargnoli J, Kim K, Lei M, Naglich JG, Pokross ME, Posy SL, Shen H, Surti N, Talbott R, Zhang Y, Terrett NK.

J Med Chem. 2015 Mar 26;58(6):2855-61. doi: 10.1021/jm501892g. Epub 2015 Mar 12.

4.

The activator of apoptosis Smac-DIABLO acts as a tetramer in solution.

Mastrangelo E, Vachette P, Cossu F, Malvezzi F, Bolognesi M, Milani M.

Biophys J. 2015 Feb 3;108(3):714-23. doi: 10.1016/j.bpj.2014.11.3471.

PMID:
25650938
5.

S-nitrosylation of XIAP at Cys 213 of BIR2 domain impairs XIAP's anti-caspase 3 activity and anti-apoptotic function.

Wu W, Wan OW, Chung KK.

Apoptosis. 2015 Apr;20(4):491-9. doi: 10.1007/s10495-015-1087-3.

PMID:
25578648
6.

Cell-permeable intrinsic cellular inhibitors of apoptosis protect and rescue intestinal epithelial cells from radiation-induced cell death.

Matsuzaki-Horibuchi S, Yasuda T, Sakaguchi N, Yamaguchi Y, Akashi M.

J Radiat Res. 2015 Jan;56(1):100-13. doi: 10.1093/jrr/rru094. Epub 2014 Oct 30.

7.

Discovery of Sanggenon G as a natural cell-permeable small-molecular weight inhibitor of X-linked inhibitor of apoptosis protein (XIAP).

Seiter MA, Salcher S, Rupp M, Hagenbuchner J, Kiechl-Kohlendorfer U, Mortier J, Wolber G, Rollinger JM, Obexer P, Ausserlechner MJ.

FEBS Open Bio. 2014 Jul 5;4:659-71. doi: 10.1016/j.fob.2014.07.001. eCollection 2014.

8.

Chemoselective Wittig and Michael ligations of unprotected peptidyl phosphoranes in water furnish potent inhibitors of caspase-3.

Holland-Nell K, Fernández-Bachiller MI, Ahsanullah, Rademann J.

Org Lett. 2014 Sep 5;16(17):4428-31. doi: 10.1021/ol501910x. Epub 2014 Aug 20.

PMID:
25141292
9.

X-linked inhibitor of apoptosis protein - a critical death resistance regulator and therapeutic target for personalized cancer therapy.

Obexer P, Ausserlechner MJ.

Front Oncol. 2014 Jul 28;4:197. doi: 10.3389/fonc.2014.00197. eCollection 2014. Review.

10.

Copper-binding properties of the BIR2 and BIR3 domains of the X-linked inhibitor of apoptosis protein.

Liang Y, Ewing PM, Laursen WJ, Tripp VT, Singh S, Splan KE.

J Inorg Biochem. 2014 Nov;140:104-10. doi: 10.1016/j.jinorgbio.2014.07.010. Epub 2014 Jul 22.

PMID:
25105866
11.

Targeting the inhibitor of Apoptosis Protein BIR3 binding domains.

Jaquith JB.

Pharm Pat Anal. 2014 May;3(3):297-312. doi: 10.4155/ppa.14.16. Review.

PMID:
24998289
12.

Direct, reagentless electrochemical detection of the BIR3 domain of X-linked inhibitor of apoptosis protein using a peptide-based conducting polymer sensor.

Wang X, Piro B, Reisberg S, Anquetin G, de Rocquigny H, Jiang P, Wang Q, Wu W, Pham MC, Dong CZ.

Biosens Bioelectron. 2014 Nov 15;61:57-62. doi: 10.1016/j.bios.2014.04.047. Epub 2014 May 9.

PMID:
24858673
13.

Molecular Dynamics simulations of Inhibitor of Apoptosis Proteins and identification of potential small molecule inhibitors.

Jayakumar J, Anishetty S.

Bioorg Med Chem Lett. 2014 May 1;24(9):2098-104. doi: 10.1016/j.bmcl.2014.03.046. Epub 2014 Mar 26.

PMID:
24717152
14.

1,2-benzisothiazol-3-one derivatives as a novel class of small-molecule caspase-3 inhibitors.

Wu L, Lu M, Yan Z, Tang X, Sun B, Liu W, Zhou H, Yang C.

Bioorg Med Chem. 2014 Apr 15;22(8):2416-26. doi: 10.1016/j.bmc.2014.03.002. Epub 2014 Mar 12.

PMID:
24656804
15.

FAIM-L is an IAP-binding protein that inhibits XIAP ubiquitinylation and protects from Fas-induced apoptosis.

Moubarak RS, Planells-Ferrer L, Urresti J, Reix S, Segura MF, Carriba P, Marqués-Fernàndez F, Sole C, Llecha-Cano N, Lopez-Soriano J, Sanchis D, Yuste VJ, Comella JX.

J Neurosci. 2013 Dec 4;33(49):19262-75. doi: 10.1523/JNEUROSCI.2479-13.2013.

16.

Optimization of benzodiazepinones as selective inhibitors of the X-linked inhibitor of apoptosis protein (XIAP) second baculovirus IAP repeat (BIR2) domain.

Kester RF, Donnell AF, Lou Y, Remiszewski SW, Lombardo LJ, Chen S, Le NT, Lo J, Moliterni JA, Han X, Hogg JH, Liang W, Michoud C, Rupert KC, Mischke S, Le K, Weisel M, Janson CA, Lukacs CM, Fretland AJ, Hong K, Polonskaia A, Gao L, Li S, Solis DS, Aguilar D, Tardell C, Dvorozniak M, Tannu S, Lee EC, Schutt AD, Goggin B.

J Med Chem. 2013 Oct 24;56(20):7788-803. doi: 10.1021/jm400732v. Epub 2013 Oct 7.

PMID:
24093940
17.

Benzazepinones and benzoxazepinones as antagonists of inhibitor of apoptosis proteins (IAPs) selective for the second baculovirus IAP repeat (BIR2) domain.

Donnell AF, Michoud C, Rupert KC, Han X, Aguilar D, Frank KB, Fretland AJ, Gao L, Goggin B, Hogg JH, Hong K, Janson CA, Kester RF, Kong N, Le K, Li S, Liang W, Lombardo LJ, Lou Y, Lukacs CM, Mischke S, Moliterni JA, Polonskaia A, Schutt AD, Solis DS, Specian A, Taylor RT, Weisel M, Remiszewski SW.

J Med Chem. 2013 Oct 24;56(20):7772-87. doi: 10.1021/jm400731m. Epub 2013 Oct 1.

PMID:
24083782
18.

Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.

Damgaard RB, Fiil BK, Speckmann C, Yabal M, zur Stadt U, Bekker-Jensen S, Jost PJ, Ehl S, Mailand N, Gyrd-Hansen M.

EMBO Mol Med. 2013 Aug;5(8):1278-95. doi: 10.1002/emmm.201303090. Epub 2013 Jul 1.

19.

Design, synthesis and evaluation of inhibitor of apoptosis protein (IAP) antagonists that are highly selective for the BIR2 domain of XIAP.

Ardecky RJ, Welsh K, Finlay D, Lee PS, González-López M, Ganji SR, Ravanan P, Mace PD, Riedl SJ, Vuori K, Reed JC, Cosford ND.

Bioorg Med Chem Lett. 2013 Jul 15;23(14):4253-7. doi: 10.1016/j.bmcl.2013.04.096. Epub 2013 May 14.

20.

Specific inhibition of caspase-3 by a competitive DARPin: molecular mimicry between native and designed inhibitors.

Schroeder T, Barandun J, Flütsch A, Briand C, Mittl PR, Grütter MG.

Structure. 2013 Feb 5;21(2):277-89. doi: 10.1016/j.str.2012.12.011. Epub 2013 Jan 17.

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