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Results: 1 to 20 of 100

1.

In silico characterization and molecular dynamics simulation of Pfcyc-1, a cyclin homolog of Plasmodium falciparum.

Kaushik A, Subramaniam S, Gupta D.

J Biomol Struct Dyn. 2014;32(10):1624-33. doi: 10.1080/07391102.2013.831378. Epub 2013 Sep 2.

PMID:
23998890
[PubMed - in process]
2.

Activation of a Plasmodium falciparum cdc2-related kinase by heterologous p25 and cyclin H. Functional characterization of a P. falciparum cyclin homologue.

Le Roch K, Sestier C, Dorin D, Waters N, Kappes B, Chakrabarti D, Meijer L, Doerig C.

J Biol Chem. 2000 Mar 24;275(12):8952-8.

PMID:
10722743
[PubMed - indexed for MEDLINE]
Free Article
3.

Identification and initial characterization of three novel cyclin-related proteins of the human malaria parasite Plasmodium falciparum.

Merckx A, Le Roch K, Nivez MP, Dorin D, Alano P, Gutierrez GJ, Nebreda AR, Goldring D, Whittle C, Patterson S, Chakrabarti D, Doerig C.

J Biol Chem. 2003 Oct 10;278(41):39839-50. Epub 2003 Jul 17.

PMID:
12869562
[PubMed - indexed for MEDLINE]
Free Article
4.

Structural model of the Plasmodium CDK, Pfmrk, a novel target for malaria therapeutics.

Peng Y, Keenan SM, Welsh WJ.

J Mol Graph Model. 2005 Sep;24(1):72-80.

PMID:
16046158
[PubMed - indexed for MEDLINE]
5.

Cyclin H activation and drug susceptibility of the Pfmrk cyclin dependent protein kinase from Plasmodium falciparum.

Waters NC, Woodard CL, Prigge ST.

Mol Biochem Parasitol. 2000 Mar 15;107(1):45-55.

PMID:
10717301
[PubMed - indexed for MEDLINE]
6.

Cyclin-dependent protein kinases as therapeutic drug targets for antimalarial drug development.

Waters NC, Geyer JA.

Expert Opin Ther Targets. 2003 Feb;7(1):7-17. Review.

PMID:
12556199
[PubMed - indexed for MEDLINE]
7.
8.

Targeting malaria with specific CDK inhibitors.

Geyer JA, Prigge ST, Waters NC.

Biochim Biophys Acta. 2005 Dec 30;1754(1-2):160-70. Epub 2005 Sep 9. Review.

PMID:
16185941
[PubMed - indexed for MEDLINE]
9.

Characteristics of the Plasmodium falciparum PK5 ATP-binding site: implications for the design of novel antimalarial agents.

Keenan SM, Welsh WJ.

J Mol Graph Model. 2004 Jan;22(3):241-7.

PMID:
14629982
[PubMed - indexed for MEDLINE]
10.

A structural annotation resource for the selection of putative target proteins in the malaria parasite.

Joubert Y, Joubert F.

Malar J. 2008 May 23;7:90. doi: 10.1186/1475-2875-7-90.

PMID:
18500983
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

The crystal structure of cyclin A.

Brown NR, Noble ME, Endicott JA, Garman EF, Wakatsuki S, Mitchell E, Rasmussen B, Hunt T, Johnson LN.

Structure. 1995 Nov 15;3(11):1235-47.

PMID:
8591034
[PubMed - indexed for MEDLINE]
12.

Characterization of Plasmodium falciparum cdc2-related kinase and the effects of a CDK inhibitor on the parasites in erythrocytic schizogony.

Iwanaga T, Sugi T, Kobayashi K, Takemae H, Gong H, Ishiwa A, Murakoshi F, Recuenco FC, Horimoto T, Akashi H, Kato K.

Parasitol Int. 2013 Oct;62(5):423-30. doi: 10.1016/j.parint.2013.05.003. Epub 2013 May 18.

PMID:
23688804
[PubMed - indexed for MEDLINE]
13.

Cyclin-dependent kinase homologues of Plasmodium falciparum.

Doerig C, Endicott J, Chakrabarti D.

Int J Parasitol. 2002 Dec 4;32(13):1575-85. Review.

PMID:
12435442
[PubMed - indexed for MEDLINE]
14.

Oxindole-based compounds are selective inhibitors of Plasmodium falciparum cyclin dependent protein kinases.

Woodard CL, Li Z, Kathcart AK, Terrell J, Gerena L, Lopez-Sanchez M, Kyle DE, Bhattacharjee AK, Nichols DA, Ellis W, Prigge ST, Geyer JA, Waters NC.

J Med Chem. 2003 Aug 28;46(18):3877-82.

PMID:
12930149
[PubMed - indexed for MEDLINE]
15.

Influence of human p16(INK4) and p21(CIP1) on the in vitro activity of recombinant Plasmodium falciparum cyclin-dependent protein kinases.

Li Z, Le Roch K, Geyer JA, Woodard CL, Prigge ST, Koh J, Doerig C, Waters NC.

Biochem Biophys Res Commun. 2001 Nov 16;288(5):1207-11.

PMID:
11700040
[PubMed - indexed for MEDLINE]
16.

Crystal structure of a viral cyclin, a positive regulator of cyclin-dependent kinase 6.

Schulze-Gahmen U, Jung JU, Kim SH.

Structure. 1999 Mar 15;7(3):245-54.

PMID:
10368294
[PubMed - indexed for MEDLINE]
17.

Identification of an effector protein and gain-of-function mutants that activate Pfmrk, a malarial cyclin-dependent protein kinase.

Chen Y, Jirage D, Caridha D, Kathcart AK, Cortes EA, Dennull RA, Geyer JA, Prigge ST, Waters NC.

Mol Biochem Parasitol. 2006 Sep;149(1):48-57. Epub 2006 May 15.

PMID:
16737745
[PubMed - indexed for MEDLINE]
18.

Several human cyclin-dependent kinase inhibitors, structurally related to roscovitine, as new anti-malarial agents.

Houzé S, Hoang NT, Lozach O, Le Bras J, Meijer L, Galons H, Demange L.

Molecules. 2014 Sep 23;19(9):15237-57. doi: 10.3390/molecules190915237.

PMID:
25255764
[PubMed - in process]
Free Article
19.

Several human cyclin-dependent kinase inhibitors, structurally related to roscovitine, are new anti-malarial agents.

Houzé S, Hoang NT, Lozach O, Le Bras J, Meijer L, Galons H, Demange L.

Molecules. 2014 Sep 23;19(9):15237-57. doi: 10.3390/molecules190915237.

PMID:
25251193
[PubMed - in process]
Free Article
20.

Identification of novel and conserved functional and structural elements of the G1 cyclin Cln3 important for interactions with the CDK Cdc28 in Saccharomyces cerevisiae.

Miller ME, Cross FR, Groeger AL, Jameson KL.

Yeast. 2005 Oct 15;22(13):1021-36.

PMID:
16200502
[PubMed - indexed for MEDLINE]

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