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Results: 1 to 20 of 120

1.

Protumorigenic actions of S100A2 involve regulation of PI3/Akt signaling and functional interaction with Smad3.

Naz S, Bashir M, Ranganathan P, Bodapati P, Santosh V, Kondaiah P.

Carcinogenesis. 2014 Jan;35(1):14-23. doi: 10.1093/carcin/bgt287. Epub 2013 Aug 29.

PMID:
23996929
[PubMed - indexed for MEDLINE]
2.

Regulation of S100A2 expression by TGF-β-induced MEK/ERK signalling and its role in cell migration/invasion.

Naz S, Ranganathan P, Bodapati P, Shastry AH, Mishra LN, Kondaiah P.

Biochem J. 2012 Oct 1;447(1):81-91. doi: 10.1042/BJ20120014.

PMID:
22747445
[PubMed - indexed for MEDLINE]
Free Article
3.

Peroxisome proliferator-activated receptor-gamma activation inhibits tumor metastasis by antagonizing Smad3-mediated epithelial-mesenchymal transition.

Reka AK, Kurapati H, Narala VR, Bommer G, Chen J, Standiford TJ, Keshamouni VG.

Mol Cancer Ther. 2010 Dec;9(12):3221-32. doi: 10.1158/1535-7163.MCT-10-0570.

PMID:
21159608
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Loss of phosphatase and tensin homologue increases transforming growth factor beta-mediated invasion with enhanced SMAD3 transcriptional activity.

Hjelmeland AB, Hjelmeland MD, Shi Q, Hart JL, Bigner DD, Wang XF, Kontos CD, Rich JN.

Cancer Res. 2005 Dec 15;65(24):11276-81.

PMID:
16357132
[PubMed - indexed for MEDLINE]
Free Article
5.

Nox4 involvement in TGF-beta and SMAD3-driven induction of the epithelial-to-mesenchymal transition and migration of breast epithelial cells.

Boudreau HE, Casterline BW, Rada B, Korzeniowska A, Leto TL.

Free Radic Biol Med. 2012 Oct 1;53(7):1489-99. doi: 10.1016/j.freeradbiomed.2012.06.016. Epub 2012 Jun 19.

PMID:
22728268
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Zyxin is a transforming growth factor-β (TGF-β)/Smad3 target gene that regulates lung cancer cell motility via integrin α5β1.

Mise N, Savai R, Yu H, Schwarz J, Kaminski N, Eickelberg O.

J Biol Chem. 2012 Sep 7;287(37):31393-405. doi: 10.1074/jbc.M112.357624. Epub 2012 Jul 9.

PMID:
22778267
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

MAWBP and MAWD inhibit proliferation and invasion in gastric cancer.

Li DM, Zhang J, Li WM, Cui JT, Pan YM, Liu SQ, Xing R, Lu YY.

World J Gastroenterol. 2013 May 14;19(18):2781-92. doi: 10.3748/wjg.v19.i18.2781.

PMID:
23687415
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Activation of AKT signaling promotes epithelial-mesenchymal transition and tumor growth in colorectal cancer cells.

Suman S, Kurisetty V, Das TP, Vadodkar A, Ramos G, Lakshmanaswamy R, Damodaran C.

Mol Carcinog. 2014 Feb;53 Suppl 1:E151-60. doi: 10.1002/mc.22076. Epub 2013 Sep 2.

PMID:
24000138
[PubMed - indexed for MEDLINE]
9.

Differential expression of S100A2 and S100A4 in lung adenocarcinomas: clinicopathological significance, relationship to p53 and identification of their target genes.

Matsubara D, Niki T, Ishikawa S, Goto A, Ohara E, Yokomizo T, Heizmann CW, Aburatani H, Moriyama S, Moriyama H, Nishimura Y, Funata N, Fukayama M.

Cancer Sci. 2005 Dec;96(12):844-57.

PMID:
16367903
[PubMed - indexed for MEDLINE]
10.

Smoking attenuates transforming growth factor-β-mediated tumor suppression function through downregulation of Smad3 in lung cancer.

Samanta D, Gonzalez AL, Nagathihalli N, Ye F, Carbone DP, Datta PK.

Cancer Prev Res (Phila). 2012 Mar;5(3):453-63. doi: 10.1158/1940-6207.CAPR-11-0313. Epub 2012 Jan 9.

PMID:
22232600
[PubMed - indexed for MEDLINE]
11.

DEAR1 is a chromosome 1p35 tumor suppressor and master regulator of TGF-β-driven epithelial-mesenchymal transition.

Chen N, Balasenthil S, Reuther J, Frayna A, Wang Y, Chandler DS, Abruzzo LV, Rashid A, Rodriguez J, Lozano G, Cao Y, Lokken E, Chen J, Frazier ML, Sahin AA, Wistuba II, Sen S, Lott ST, Killary AM.

Cancer Discov. 2013 Oct;3(10):1172-89. doi: 10.1158/2159-8290.CD-12-0499. Epub 2013 Jul 9.

PMID:
23838884
[PubMed - indexed for MEDLINE]
12.

Functional interaction between Smad3 and S100A4 (metastatin-1) for TGF-beta-mediated cancer cell invasiveness.

Matsuura I, Lai CY, Chiang KN.

Biochem J. 2010 Feb 24;426(3):327-35. doi: 10.1042/BJ20090990.

PMID:
20070253
[PubMed - indexed for MEDLINE]
Free Article
13.

Transforming growth factor-β1 induces epithelial-to-mesenchymal transition in human lung cancer cells via PI3K/Akt and MEK/Erk1/2 signaling pathways.

Chen XF, Zhang HJ, Wang HB, Zhu J, Zhou WY, Zhang H, Zhao MC, Su JM, Gao W, Zhang L, Fei K, Zhang HT, Wang HY.

Mol Biol Rep. 2012 Apr;39(4):3549-56. doi: 10.1007/s11033-011-1128-0. Epub 2011 Jun 29.

PMID:
21713404
[PubMed - indexed for MEDLINE]
14.

S100A2 promoter-driven conditionally replicative adenovirus targets non-small-cell lung carcinoma.

Lee K, Yun ST, Yun CO, Ahn BY, Jo EC.

Gene Ther. 2012 Oct;19(10):967-77. doi: 10.1038/gt.2011.168. Epub 2011 Oct 27.

PMID:
22033466
[PubMed - indexed for MEDLINE]
15.

TGF-β and Smad3 modulate PI3K/Akt signaling pathway in vascular smooth muscle cells.

Suwanabol PA, Seedial SM, Zhang F, Shi X, Si Y, Liu B, Kent KC.

Am J Physiol Heart Circ Physiol. 2012 Jun 1;302(11):H2211-9. doi: 10.1152/ajpheart.00966.2011. Epub 2012 Mar 23. Erratum in: Am J Physiol Heart Circ Physiol. 2014 Jun 1;306(11):H1594.

PMID:
22447946
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

c-Jun N-terminal kinase 1 promotes transforming growth factor-β1-induced epithelial-to-mesenchymal transition via control of linker phosphorylation and transcriptional activity of Smad3.

Velden JL, Alcorn JF, Guala AS, Badura EC, Janssen-Heininger YM.

Am J Respir Cell Mol Biol. 2011 Apr;44(4):571-81. doi: 10.1165/rcmb.2009-0282OC. Epub 2010 Jun 25.

PMID:
20581097
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Akt/PKB-mediated phosphorylation of Twist1 promotes tumor metastasis via mediating cross-talk between PI3K/Akt and TGF-β signaling axes.

Xue G, Restuccia DF, Lan Q, Hynx D, Dirnhofer S, Hess D, Rüegg C, Hemmings BA.

Cancer Discov. 2012 Mar;2(3):248-59. doi: 10.1158/2159-8290.CD-11-0270. Epub 2012 Jan 25.

PMID:
22585995
[PubMed - indexed for MEDLINE]
18.

MiR-155-mediated loss of C/EBPβ shifts the TGF-β response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer.

Johansson J, Berg T, Kurzejamska E, Pang MF, Tabor V, Jansson M, Roswall P, Pietras K, Sund M, Religa P, Fuxe J.

Oncogene. 2013 Dec 12;32(50):5614-24. doi: 10.1038/onc.2013.322. Epub 2013 Aug 19.

PMID:
23955085
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Transforming growth factor-beta1, transforming growth factor-beta2, and transforming growth factor-beta3 enhance ovarian cancer metastatic potential by inducing a Smad3-dependent epithelial-to-mesenchymal transition.

Do TV, Kubba LA, Du H, Sturgis CD, Woodruff TK.

Mol Cancer Res. 2008 May;6(5):695-705. doi: 10.1158/1541-7786.MCR-07-0294.

PMID:
18505915
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Resveratrol inhibits the epithelial-mesenchymal transition of pancreatic cancer cells via suppression of the PI-3K/Akt/NF-κB pathway.

Li W, Ma J, Ma Q, Li B, Han L, Liu J, Xu Q, Duan W, Yu S, Wang F, Wu E.

Curr Med Chem. 2013;20(33):4185-94.

PMID:
23992306
[PubMed - indexed for MEDLINE]
Free PMC Article

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