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Results: 1 to 20 of 120

1.

An essential role for Rab27a GTPase in eosinophil exocytosis.

Kim JD, Willetts L, Ochkur S, Srivastava N, Hamburg R, Shayeganpour A, Seabra MC, Lee JJ, Moqbel R, Lacy P.

J Leukoc Biol. 2013 Dec;94(6):1265-74. doi: 10.1189/jlb.0812431. Epub 2013 Aug 28.

PMID:
23986549
[PubMed - indexed for MEDLINE]
2.

Differential expression and activation of Rab27A in human eosinophils: relationship to blood eosinophilia.

Coughlin JJ, Odemuyiwa SO, Davidson CE, Moqbel R.

Biochem Biophys Res Commun. 2008 Aug 29;373(3):382-6. doi: 10.1016/j.bbrc.2008.06.033. Epub 2008 Jun 20.

PMID:
18571497
[PubMed - indexed for MEDLINE]
3.

Distinct and opposing roles for Rab27a/Mlph/MyoVa and Rab27b/Munc13-4 in mast cell secretion.

Singh RK, Mizuno K, Wasmeier C, Wavre-Shapton ST, Recchi C, Catz SD, Futter C, Tolmachova T, Hume AN, Seabra MC.

FEBS J. 2013 Feb;280(3):892-903. doi: 10.1111/febs.12081. Epub 2013 Jan 2.

PMID:
23281710
[PubMed - indexed for MEDLINE]
4.

Agonist activation of f-actin-mediated eosinophil shape change and mediator release is dependent on Rac2.

Lacy P, Willetts L, Kim JD, Lo AN, Lam B, Maclean EI, Moqbel R, Rothenberg ME, Zimmermann N.

Int Arch Allergy Immunol. 2011;156(2):137-47. doi: 10.1159/000322597. Epub 2011 May 16.

PMID:
21576984
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Degranulation status of airway tissue eosinophils in mouse models of allergic airway inflammation.

Malm-Erjefält M, Persson CG, Erjefält JS.

Am J Respir Cell Mol Biol. 2001 Mar;24(3):352-9.

PMID:
11245636
[PubMed - indexed for MEDLINE]
6.

A sensitive high throughput ELISA for human eosinophil peroxidase: a specific assay to quantify eosinophil degranulation from patient-derived sources.

Ochkur SI, Kim JD, Protheroe CA, Colbert D, Condjella RM, Bersoux S, Helmers RA, Moqbel R, Lacy P, Kelly EA, Jarjour NN, Kern R, Peters A, Schleimer RP, Furuta GT, Nair P, Lee JJ, Lee NA.

J Immunol Methods. 2012 Oct 31;384(1-2):10-20. doi: 10.1016/j.jim.2012.06.011. Epub 2012 Jun 28.

PMID:
22750539
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

The development of a sensitive and specific ELISA for mouse eosinophil peroxidase: assessment of eosinophil degranulation ex vivo and in models of human disease.

Ochkur SI, Kim JD, Protheroe CA, Colbert D, Moqbel R, Lacy P, Lee JJ, Lee NA.

J Immunol Methods. 2012 Jan 31;375(1-2):138-47. doi: 10.1016/j.jim.2011.10.002. Epub 2011 Oct 12.

PMID:
22019643
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Nonpathogenic, environmental fungi induce activation and degranulation of human eosinophils.

Inoue Y, Matsuwaki Y, Shin SH, Ponikau JU, Kita H.

J Immunol. 2005 Oct 15;175(8):5439-47.

PMID:
16210651
[PubMed - indexed for MEDLINE]
Free Article
9.

SIRPα/CD172a regulates eosinophil homeostasis.

Verjan Garcia N, Umemoto E, Saito Y, Yamasaki M, Hata E, Matozaki T, Murakami M, Jung YJ, Woo SY, Seoh JY, Jang MH, Aozasa K, Miyasaka M.

J Immunol. 2011 Sep 1;187(5):2268-77. doi: 10.4049/jimmunol.1101008. Epub 2011 Jul 20.

PMID:
21775684
[PubMed - indexed for MEDLINE]
Free Article
10.

[Eosinophil and neutrophil degranulation in allergic inflammation: immunohistochemical localization of granule proteins in fatal asthma and stimulus-dependent degranulation in vitro].

Fujisawa T, Kita H, Sur S, Kobayashi K.

Nihon Kyobu Shikkan Gakkai Zasshi. 1993 Dec;31 Suppl:115-24. Japanese.

PMID:
8007454
[PubMed - indexed for MEDLINE]
11.

Eosinophil degranulation in the allergic lung of mice primarily occurs in the airway lumen.

Clark K, Simson L, Newcombe N, Koskinen AM, Mattes J, Lee NA, Lee JJ, Dent LA, Matthaei KI, Foster PS.

J Leukoc Biol. 2004 Jun;75(6):1001-9. Epub 2004 Mar 12.

PMID:
15020648
[PubMed - indexed for MEDLINE]
Free Article
12.

Circulating eosinophils in asthma, allergic rhinitis, and atopic dermatitis lack morphological signs of degranulation.

Malm-Erjefält M, Greiff L, Ankerst J, Andersson M, Wallengren J, Cardell LO, Rak S, Persson CG, Erjefält JS.

Clin Exp Allergy. 2005 Oct;35(10):1334-40.

PMID:
16238793
[PubMed - indexed for MEDLINE]
13.

The effect of IL-5 and eotaxin expression in the lung on eosinophil trafficking and degranulation and the induction of bronchial hyperreactivity.

Mould AW, Ramsay AJ, Matthaei KI, Young IG, Rothenberg ME, Foster PS.

J Immunol. 2000 Feb 15;164(4):2142-50.

PMID:
10657668
[PubMed - indexed for MEDLINE]
Free Article
14.

Degranulation patterns of eosinophil granulocytes as determinants of eosinophil driven disease.

Erjefält JS, Greiff L, Andersson M, Adelroth E, Jeffery PK, Persson CG.

Thorax. 2001 May;56(5):341-4.

PMID:
11312400
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Urinary eosinophil-derived neurotoxin/protein X: a simple method for assessing eosinophil degranulation in vivo.

Cottin V, Deviller P, Tardy F, Cordier JF.

J Allergy Clin Immunol. 1998 Jan;101(1 Pt 1):116-23.

PMID:
9449510
[PubMed - indexed for MEDLINE]
16.

Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma.

Ochkur SI, Jacobsen EA, Protheroe CA, Biechele TL, Pero RS, McGarry MP, Wang H, O'Neill KR, Colbert DC, Colby TV, Shen H, Blackburn MR, Irvin CC, Lee JJ, Lee NA.

J Immunol. 2007 Jun 15;178(12):7879-89.

PMID:
17548626
[PubMed - indexed for MEDLINE]
Free Article
17.

Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor.

Dyer KD, Percopo CM, Xie Z, Yang Z, Kim JD, Davoine F, Lacy P, Druey KM, Moqbel R, Rosenberg HF.

J Immunol. 2010 Jun 1;184(11):6327-34. doi: 10.4049/jimmunol.0904043. Epub 2010 Apr 26.

PMID:
20421642
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Defective granule exocytosis in Rab27a-deficient lymphocytes from Ashen mice.

Haddad EK, Wu X, Hammer JA 3rd, Henkart PA.

J Cell Biol. 2001 Feb 19;152(4):835-42.

PMID:
11266473
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Eosinophils in allergy: role in disease, degranulation, and cytokines.

Martin LB, Kita H, Leiferman KM, Gleich GJ.

Int Arch Allergy Immunol. 1996 Mar;109(3):207-15. Review.

PMID:
8620088
[PubMed - indexed for MEDLINE]
20.

Kinetics of Rab27a-dependent actions on vesicle docking and priming in pancreatic beta-cells.

Merrins MJ, Stuenkel EL.

J Physiol. 2008 Nov 15;586(Pt 22):5367-81. doi: 10.1113/jphysiol.2008.158477. Epub 2008 Sep 18.

PMID:
18801842
[PubMed - indexed for MEDLINE]
Free PMC Article

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