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Results: 1 to 20 of 93

1.

Translational up-regulation of polycystic kidney disease protein PKD2 by endoplasmic reticulum stress.

Yang J, Zheng W, Wang Q, Lara C, Hussein S, Chen XZ.

FASEB J. 2013 Dec;27(12):4998-5009. doi: 10.1096/fj.13-236075. Epub 2013 Aug 28.

PMID:
23985800
[PubMed - indexed for MEDLINE]
2.

An upstream open reading frame regulates translation of GADD34 during cellular stresses that induce eIF2alpha phosphorylation.

Lee YY, Cevallos RC, Jan E.

J Biol Chem. 2009 Mar 13;284(11):6661-73. doi: 10.1074/jbc.M806735200. Epub 2009 Jan 8.

PMID:
19131336
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.

Guan BJ, Krokowski D, Majumder M, Schmotzer CL, Kimball SR, Merrick WC, Koromilas AE, Hatzoglou M.

J Biol Chem. 2014 May 2;289(18):12593-611. doi: 10.1074/jbc.M113.543215. Epub 2014 Mar 19.

PMID:
24648524
[PubMed - indexed for MEDLINE]
4.

Polycystin-2 down-regulates cell proliferation via promoting PERK-dependent phosphorylation of eIF2alpha.

Liang G, Yang J, Wang Z, Li Q, Tang Y, Chen XZ.

Hum Mol Genet. 2008 Oct 15;17(20):3254-62. doi: 10.1093/hmg/ddn221. Epub 2008 Jul 29.

PMID:
18664456
[PubMed - indexed for MEDLINE]
Free Article
5.

Activating transcription factor 4 is translationally regulated by hypoxic stress.

Blais JD, Filipenko V, Bi M, Harding HP, Ron D, Koumenis C, Wouters BG, Bell JC.

Mol Cell Biol. 2004 Sep;24(17):7469-82.

PMID:
15314157
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation.

Streets AJ, Wessely O, Peters DJ, Ong AC.

Hum Mol Genet. 2013 May 15;22(10):1924-39. doi: 10.1093/hmg/ddt031. Epub 2013 Feb 5.

PMID:
23390129
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Regulation of internal ribosome entry site-mediated translation by eukaryotic initiation factor-2alpha phosphorylation and translation of a small upstream open reading frame.

Fernandez J, Yaman I, Merrick WC, Koromilas A, Wek RC, Sood R, Hensold J, Hatzoglou M.

J Biol Chem. 2002 Jan 18;277(3):2050-8. Epub 2001 Oct 29.

PMID:
11684693
[PubMed - indexed for MEDLINE]
Free Article
8.

Coordinate regulation of eIF2α phosphorylation by PPP1R15 and GCN2 is required during Drosophila development.

Malzer E, Szajewska-Skuta M, Dalton LE, Thomas SE, Hu N, Skaer H, Lomas DA, Crowther DC, Marciniak SJ.

J Cell Sci. 2013 Mar 15;126(Pt 6):1406-15. doi: 10.1242/jcs.117614. Epub 2013 Feb 15.

PMID:
23418347
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Cyst formation in kidney via B-Raf signaling in the PKD2 transgenic mice.

Park EY, Sung YH, Yang MH, Noh JY, Park SY, Lee TY, Yook YJ, Yoo KH, Roh KJ, Kim I, Hwang YH, Oh GT, Seong JK, Ahn C, Lee HW, Park JH.

J Biol Chem. 2009 Mar 13;284(11):7214-22. doi: 10.1074/jbc.M805890200. Epub 2008 Dec 20.

PMID:
19098310
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Regulation of protein synthesis by hypoxia via activation of the endoplasmic reticulum kinase PERK and phosphorylation of the translation initiation factor eIF2alpha.

Koumenis C, Naczki C, Koritzinsky M, Rastani S, Diehl A, Sonenberg N, Koromilas A, Wouters BG.

Mol Cell Biol. 2002 Nov;22(21):7405-16.

PMID:
12370288
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Role of the endoplasmic reticulum unfolded protein response in glomerular epithelial cell injury.

Cybulsky AV, Takano T, Papillon J, Bijian K.

J Biol Chem. 2005 Jul 1;280(26):24396-403. Epub 2005 Apr 29.

PMID:
15863508
[PubMed - indexed for MEDLINE]
Free Article
12.

Novel PKD1 and PKD2 mutations in autosomal dominant polycystic kidney disease (ADPKD).

Hoefele J, Mayer K, Scholz M, Klein HG.

Nephrol Dial Transplant. 2011 Jul;26(7):2181-8. doi: 10.1093/ndt/gfq720. Epub 2010 Nov 29.

PMID:
21115670
[PubMed - indexed for MEDLINE]
Free Article
13.

Control of PERK eIF2alpha kinase activity by the endoplasmic reticulum stress-induced molecular chaperone P58IPK.

Yan W, Frank CL, Korth MJ, Sopher BL, Novoa I, Ron D, Katze MG.

Proc Natl Acad Sci U S A. 2002 Dec 10;99(25):15920-5. Epub 2002 Nov 22.

PMID:
12446838
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Endoplasmic reticulum stress response mediated by the PERK-eIF2(alpha)-ATF4 pathway is involved in osteoblast differentiation induced by BMP2.

Saito A, Ochiai K, Kondo S, Tsumagari K, Murakami T, Cavener DR, Imaizumi K.

J Biol Chem. 2011 Feb 11;286(6):4809-18. doi: 10.1074/jbc.M110.152900. Epub 2010 Dec 6.

PMID:
21135100
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Regulation of internal ribosomal entry site-mediated translation by phosphorylation of the translation initiation factor eIF2alpha.

Fernandez J, Yaman I, Sarnow P, Snider MD, Hatzoglou M.

J Biol Chem. 2002 May 24;277(21):19198-205. Epub 2002 Mar 4.

PMID:
11877448
[PubMed - indexed for MEDLINE]
Free Article
16.

Cellular activation triggered by the autosomal dominant polycystic kidney disease gene product PKD2.

Arnould T, Sellin L, Benzing T, Tsiokas L, Cohen HT, Kim E, Walz G.

Mol Cell Biol. 1999 May;19(5):3423-34.

PMID:
10207066
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Methods for analyzing eIF2 kinases and translational control in the unfolded protein response.

Teske BF, Baird TD, Wek RC.

Methods Enzymol. 2011;490:333-56. doi: 10.1016/B978-0-12-385114-7.00019-2.

PMID:
21266259
[PubMed - indexed for MEDLINE]
18.

6-Shogaol induces apoptosis in human hepatocellular carcinoma cells and exhibits anti-tumor activity in vivo through endoplasmic reticulum stress.

Hu R, Zhou P, Peng YB, Xu X, Ma J, Liu Q, Zhang L, Wen XD, Qi LW, Gao N, Li P.

PLoS One. 2012;7(6):e39664. doi: 10.1371/journal.pone.0039664. Epub 2012 Jun 29.

PMID:
22768104
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Translation of the human erythropoietin transcript is regulated by an upstream open reading frame in response to hypoxia.

Barbosa C, Romão L.

RNA. 2014 May;20(5):594-608. doi: 10.1261/rna.040915.113. Epub 2014 Mar 19.

PMID:
24647661
[PubMed - indexed for MEDLINE]
20.

Evidence for pathogenicity of atypical splice mutations in autosomal dominant polycystic kidney disease.

Wang K, Zhao X, Chan S, Cil O, He N, Song X, Paterson AD, Pei Y.

Clin J Am Soc Nephrol. 2009 Feb;4(2):442-9. doi: 10.2215/CJN.00980208. Epub 2009 Jan 21.

PMID:
19158373
[PubMed - indexed for MEDLINE]
Free PMC Article

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