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Items: 1 to 20 of 119

1.

Theoretical insights into catalytic mechanism of protein arginine methyltransferase 1.

Zhang R, Li X, Liang Z, Zhu K, Lu J, Kong X, Ouyang S, Li L, Zheng YG, Luo C.

PLoS One. 2013 Aug 20;8(8):e72424. doi: 10.1371/journal.pone.0072424. eCollection 2013.

2.
3.

A remodeled protein arginine methyltransferase 1 (PRMT1) generates symmetric dimethylarginine.

Gui S, Gathiaka S, Li J, Qu J, Acevedo O, Hevel JM.

J Biol Chem. 2014 Mar 28;289(13):9320-7. doi: 10.1074/jbc.M113.535278. Epub 2014 Jan 29.

4.

Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8.

Zhang X, Bruice TC.

Biochemistry. 2008 Jun 24;47(25):6671-7. doi: 10.1021/bi800244s.

PMID:
18512960
5.

Förster resonance energy transfer measurements of cofactor-dependent effects on protein arginine N-methyltransferase homodimerization.

Thomas D, Lakowski TM, Pak ML, Kim JJ, Frankel A.

Protein Sci. 2010 Nov;19(11):2141-51. doi: 10.1002/pro.492.

6.

Peptide backbone conformation affects the substrate preference of protein arginine methyltransferase I.

Kölbel K, Ihling C, Kühn U, Neundorf I, Otto S, Stichel J, Robaa D, Beck-Sickinger AG, Sinz A, Wahle E.

Biochemistry. 2012 Jul 10;51(27):5463-75. Epub 2012 Jun 27.

PMID:
22697391
7.

PRMT1 is the predominant type I protein arginine methyltransferase in mammalian cells.

Tang J, Frankel A, Cook RJ, Kim S, Paik WK, Williams KR, Clarke S, Herschman HR.

J Biol Chem. 2000 Mar 17;275(11):7723-30.

8.

Substrate-induced control of product formation by protein arginine methyltransferase 1.

Gui S, Wooderchak-Donahue WL, Zang T, Chen D, Daly MP, Zhou ZS, Hevel JM.

Biochemistry. 2013 Jan 8;52(1):199-209. doi: 10.1021/bi301283t. Epub 2012 Dec 21.

PMID:
23214442
10.

Catalytic mechanism and product specificity of rubisco large subunit methyltransferase: QM/MM and MD investigations.

Zhang X, Bruice TC.

Biochemistry. 2007 May 8;46(18):5505-14. Epub 2007 Apr 13.

PMID:
17429949
11.

In vitro methylation assay to study protein arginine methylation.

Bikkavilli RK, Avasarala S, Van Scoyk M, Karuppusamy Rathinam MK, Tauler J, Borowicz S, Winn RA.

J Vis Exp. 2014 Oct 5;(92):e51997. doi: 10.3791/51997.

PMID:
25350748
12.

Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues.

Wang R, Zheng W, Yu H, Deng H, Luo M.

J Am Chem Soc. 2011 May 25;133(20):7648-51. doi: 10.1021/ja2006719. Epub 2011 May 3.

13.

A transient kinetic analysis of PRMT1 catalysis.

Feng Y, Xie N, Jin M, Stahley MR, Stivers JT, Zheng YG.

Biochemistry. 2011 Aug 16;50(32):7033-44. doi: 10.1021/bi200456u. Epub 2011 Jul 21.

14.

Substrate profiling of PRMT1 reveals amino acid sequences that extend beyond the "RGG" paradigm.

Wooderchak WL, Zang T, Zhou ZS, Acuña M, Tahara SM, Hevel JM.

Biochemistry. 2008 Sep 9;47(36):9456-66. doi: 10.1021/bi800984s. Epub 2008 Aug 13.

PMID:
18700728
15.

Investigation of the molecular origins of protein-arginine methyltransferase I (PRMT1) product specificity reveals a role for two conserved methionine residues.

Gui S, Wooderchak WL, Daly MP, Porter PJ, Johnson SJ, Hevel JM.

J Biol Chem. 2011 Aug 19;286(33):29118-26. doi: 10.1074/jbc.M111.224097. Epub 2011 Jun 21.

16.

Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1.

Dowden J, Pike RA, Parry RV, Hong W, Muhsen UA, Ward SG.

Org Biomol Chem. 2011 Oct 26;9(22):7814-21. doi: 10.1039/c1ob06100c. Epub 2011 Sep 27.

PMID:
21952734
17.

Protein arginine N-methyltransferase substrate preferences for different nη-substituted arginyl peptides.

Thomas D, Koopmans T, Lakowski TM, Kreinin H, Vhuiyan MI, Sedlock SA, Bui JM, Martin NI, Frankel A.

Chembiochem. 2014 Jul 21;15(11):1607-13. doi: 10.1002/cbic.201402045. Epub 2014 Jul 8.

PMID:
25044481
18.

A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism.

Lakowski TM, Frankel A.

J Biol Chem. 2008 Apr 11;283(15):10015-25. doi: 10.1074/jbc.M710176200. Epub 2008 Feb 8.

19.

Structural determinants for the strict monomethylation activity by trypanosoma brucei protein arginine methyltransferase 7.

Wang C, Zhu Y, Caceres TB, Liu L, Peng J, Wang J, Chen J, Chen X, Zhang Z, Zuo X, Gong Q, Teng M, Hevel JM, Wu J, Shi Y.

Structure. 2014 May 6;22(5):756-68. doi: 10.1016/j.str.2014.03.003. Epub 2014 Apr 10.

20.

Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1.

Rust HL, Zurita-Lopez CI, Clarke S, Thompson PR.

Biochemistry. 2011 Apr 26;50(16):3332-45. doi: 10.1021/bi102022e. Epub 2011 Apr 1.

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