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Changes in effective connectivity by propofol sedation.

Gómez F, Phillips C, Soddu A, Boly M, Boveroux P, Vanhaudenhuyse A, Bruno MA, Gosseries O, Bonhomme V, Laureys S, Noirhomme Q.

PLoS One. 2013 Aug 19;8(8):e71370. doi: 10.1371/journal.pone.0071370. eCollection 2013.


Posterior cingulate cortex-related co-activation patterns: a resting state FMRI study in propofol-induced loss of consciousness.

Amico E, Gomez F, Di Perri C, Vanhaudenhuyse A, Lesenfants D, Boveroux P, Bonhomme V, Brichant JF, Marinazzo D, Laureys S.

PLoS One. 2014 Jun 30;9(6):e100012. doi: 10.1371/journal.pone.0100012. eCollection 2014.


Breakdown of within- and between-network resting state functional magnetic resonance imaging connectivity during propofol-induced loss of consciousness.

Boveroux P, Vanhaudenhuyse A, Bruno MA, Noirhomme Q, Lauwick S, Luxen A, Degueldre C, Plenevaux A, Schnakers C, Phillips C, Brichant JF, Bonhomme V, Maquet P, Greicius MD, Laureys S, Boly M.

Anesthesiology. 2010 Nov;113(5):1038-53. doi: 10.1097/ALN.0b013e3181f697f5.


Directional connectivity between frontal and posterior brain regions is altered with increasing concentrations of propofol.

Maksimow A, Silfverhuth M, Långsjö J, Kaskinoro K, Georgiadis S, Jääskeläinen S, Scheinin H.

PLoS One. 2014 Nov 24;9(11):e113616. doi: 10.1371/journal.pone.0113616. eCollection 2014.


Connectivity changes underlying spectral EEG changes during propofol-induced loss of consciousness.

Boly M, Moran R, Murphy M, Boveroux P, Bruno MA, Noirhomme Q, Ledoux D, Bonhomme V, Brichant JF, Tononi G, Laureys S, Friston K.

J Neurosci. 2012 May 16;32(20):7082-90. doi: 10.1523/JNEUROSCI.3769-11.2012.


Simultaneous electroencephalographic and functional magnetic resonance imaging indicate impaired cortical top-down processing in association with anesthetic-induced unconsciousness.

Jordan D, Ilg R, Riedl V, Schorer A, Grimberg S, Neufang S, Omerovic A, Berger S, Untergehrer G, Preibisch C, Schulz E, Schuster T, Schröter M, Spoormaker V, Zimmer C, Hemmer B, Wohlschläger A, Kochs EF, Schneider G.

Anesthesiology. 2013 Nov;119(5):1031-42. doi: 10.1097/ALN.0b013e3182a7ca92.


Cortical and subcortical connectivity changes during decreasing levels of consciousness in humans: a functional magnetic resonance imaging study using propofol.

Mhuircheartaigh RN, Rosenorn-Lanng D, Wise R, Jbabdi S, Rogers R, Tracey I.

J Neurosci. 2010 Jul 7;30(27):9095-102. doi: 10.1523/JNEUROSCI.5516-09.2010.


Brain functional integration decreases during propofol-induced loss of consciousness.

Schrouff J, Perlbarg V, Boly M, Marrelec G, Boveroux P, Vanhaudenhuyse A, Bruno MA, Laureys S, Phillips C, Pélégrini-Issac M, Maquet P, Benali H.

Neuroimage. 2011 Jul 1;57(1):198-205. doi: 10.1016/j.neuroimage.2011.04.020. Epub 2011 Apr 16.


Thalamus, brainstem and salience network connectivity changes during propofol-induced sedation and unconsciousness.

Guldenmund P, Demertzi A, Boveroux P, Boly M, Vanhaudenhuyse A, Bruno MA, Gosseries O, Noirhomme Q, Brichant JF, Bonhomme V, Laureys S, Soddu A.

Brain Connect. 2013;3(3):273-85. doi: 10.1089/brain.2012.0117.


Spatiotemporal reconfiguration of large-scale brain functional networks during propofol-induced loss of consciousness.

Schröter MS, Spoormaker VI, Schorer A, Wohlschläger A, Czisch M, Kochs EF, Zimmer C, Hemmer B, Schneider G, Jordan D, Ilg R.

J Neurosci. 2012 Sep 12;32(37):12832-40. doi: 10.1523/JNEUROSCI.6046-11.2012.


Dynamic change of global and local information processing in propofol-induced loss and recovery of consciousness.

Monti MM, Lutkenhoff ES, Rubinov M, Boveroux P, Vanhaudenhuyse A, Gosseries O, Bruno MA, Noirhomme Q, Boly M, Laureys S.

PLoS Comput Biol. 2013;9(10):e1003271. doi: 10.1371/journal.pcbi.1003271. Epub 2013 Oct 17.


Propofol disrupts functional interactions between sensory and high-order processing of auditory verbal memory.

Liu X, Lauer KK, Ward BD, Rao SM, Li SJ, Hudetz AG.

Hum Brain Mapp. 2012 Oct;33(10):2487-98. doi: 10.1002/hbm.21385. Epub 2011 Sep 20.


Differential effects of deep sedation with propofol on the specific and nonspecific thalamocortical systems: a functional magnetic resonance imaging study.

Liu X, Lauer KK, Ward BD, Li SJ, Hudetz AG.

Anesthesiology. 2013 Jan;118(1):59-69. doi: 10.1097/ALN.0b013e318277a801.


Multiphasic modification of intrinsic functional connectivity of the rat brain during increasing levels of propofol.

Liu X, Pillay S, Li R, Vizuete JA, Pechman KR, Schmainda KM, Hudetz AG.

Neuroimage. 2013 Dec;83:581-92. doi: 10.1016/j.neuroimage.2013.07.003. Epub 2013 Jul 10.


The thalamus and brainstem act as key hubs in alterations of human brain network connectivity induced by mild propofol sedation.

Gili T, Saxena N, Diukova A, Murphy K, Hall JE, Wise RG.

J Neurosci. 2013 Feb 27;33(9):4024-31. doi: 10.1523/JNEUROSCI.3480-12.2013.


Propofol attenuates responses of the auditory cortex to acoustic stimulation in a dose-dependent manner: a FMRI study.

Dueck MH, Petzke F, Gerbershagen HJ, Paul M, Hesselmann V, Girnus R, Krug B, Sorger B, Goebel R, Lehrke R, Sturm V, Boerner U.

Acta Anaesthesiol Scand. 2005 Jul;49(6):784-91.


Auditory processing during deep propofol sedation and recovery from unconsciousness.

Koelsch S, Heinke W, Sammler D, Olthoff D.

Clin Neurophysiol. 2006 Aug;117(8):1746-59. Epub 2006 Jun 27.


Increased precuneus connectivity during propofol sedation.

Liu X, Li SJ, Hudetz AG.

Neurosci Lett. 2014 Feb 21;561:18-23. doi: 10.1016/j.neulet.2013.12.047. Epub 2013 Dec 25.


Rapid fragmentation of neuronal networks at the onset of propofol-induced unconsciousness.

Lewis LD, Weiner VS, Mukamel EA, Donoghue JA, Eskandar EN, Madsen JR, Anderson WS, Hochberg LR, Cash SS, Brown EN, Purdon PL.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):E3377-86. doi: 10.1073/pnas.1210907109. Epub 2012 Nov 5.

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