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Results: 1 to 20 of 100

1.

Enhanced taupathy and AD-like pathology in aged primate brains decades after infantile exposure to lead (Pb).

Bihaqi SW, Zawia NH.

Neurotoxicology. 2013 Dec;39:95-101. doi: 10.1016/j.neuro.2013.07.010. Epub 2013 Aug 21.

PMID:
23973560
[PubMed - indexed for MEDLINE]
2.

Infantile postnatal exposure to lead (Pb) enhances tau expression in the cerebral cortex of aged mice: Relevance to AD.

Bihaqi SW, Bahmani A, Adem A, Zawia NH.

Neurotoxicology. 2014 Jun 20;44C:114-120. doi: 10.1016/j.neuro.2014.06.008. [Epub ahead of print]

PMID:
24954411
[PubMed - as supplied by publisher]
3.

Interplay between cyclin-dependent kinase 5 and glycogen synthase kinase 3 beta mediated by neuregulin signaling leads to differential effects on tau phosphorylation and amyloid precursor protein processing.

Wen Y, Planel E, Herman M, Figueroa HY, Wang L, Liu L, Lau LF, Yu WH, Duff KE.

J Neurosci. 2008 Mar 5;28(10):2624-32. doi: 10.1523/JNEUROSCI.5245-07.2008.

PMID:
18322105
[PubMed - indexed for MEDLINE]
Free Article
4.

Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD.

Wu J, Basha MR, Brock B, Cox DP, Cardozo-Pelaez F, McPherson CA, Harry J, Rice DC, Maloney B, Chen D, Lahiri DK, Zawia NH.

J Neurosci. 2008 Jan 2;28(1):3-9. doi: 10.1523/JNEUROSCI.4405-07.2008.

PMID:
18171917
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Infant exposure to lead (Pb) and epigenetic modifications in the aging primate brain: implications for Alzheimer's disease.

Bihaqi SW, Huang H, Wu J, Zawia NH.

J Alzheimers Dis. 2011;27(4):819-33. doi: 10.3233/JAD-2011-111013.

PMID:
21891863
[PubMed - indexed for MEDLINE]
6.

Deregulated Cdk5 activity is involved in inducing Alzheimer's disease.

Shukla V, Skuntz S, Pant HC.

Arch Med Res. 2012 Nov;43(8):655-62. doi: 10.1016/j.arcmed.2012.10.015. Epub 2012 Nov 7. Review.

PMID:
23142263
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression.

Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, Richardson JC, Yan SD, Hanger DP, Allan SM, Sutherland C.

J Neurochem. 2007 Nov;103(3):1132-44. Epub 2007 Aug 7.

PMID:
17683481
[PubMed - indexed for MEDLINE]
8.

p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro.

Town T, Zolton J, Shaffner R, Schnell B, Crescentini R, Wu Y, Zeng J, DelleDonne A, Obregon D, Tan J, Mullan M.

J Neurosci Res. 2002 Aug 1;69(3):362-72.

PMID:
12125077
[PubMed - indexed for MEDLINE]
9.

Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1).

Giusti-Rodríguez P, Gao J, Gräff J, Rei D, Soda T, Tsai LH.

J Neurosci. 2011 Nov 2;31(44):15751-6. doi: 10.1523/JNEUROSCI.3588-11.2011.

PMID:
22049418
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Hypoxia increases Aβ-induced tau phosphorylation by calpain and promotes behavioral consequences in AD transgenic mice.

Gao L, Tian S, Gao H, Xu Y.

J Mol Neurosci. 2013 Sep;51(1):138-47. doi: 10.1007/s12031-013-9966-y. Epub 2013 Jan 24.

PMID:
23345083
[PubMed - indexed for MEDLINE]
11.

Chronic copper exposure exacerbates both amyloid and tau pathology and selectively dysregulates cdk5 in a mouse model of AD.

Kitazawa M, Cheng D, Laferla FM.

J Neurochem. 2009 Mar;108(6):1550-60. doi: 10.1111/j.1471-4159.2009.05901.x. Epub 2009 Jan 22.

PMID:
19183260
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Suppression of cyclin-dependent kinase 5 activation by amyloid precursor protein: a novel excitoprotective mechanism involving modulation of tau phosphorylation.

Han P, Dou F, Li F, Zhang X, Zhang YW, Zheng H, Lipton SA, Xu H, Liao FF.

J Neurosci. 2005 Dec 14;25(50):11542-52.

PMID:
16354912
[PubMed - indexed for MEDLINE]
Free Article
13.

CD40 ligation mediates plaque-associated tau phosphorylation in beta-amyloid overproducing mice.

Laporte V, Ait-Ghezala G, Volmar CH, Ganey C, Ganey N, Wood M, Mullan M.

Brain Res. 2008 Sep 22;1231:132-42. doi: 10.1016/j.brainres.2008.06.032. Epub 2008 Jun 19.

PMID:
18606155
[PubMed - indexed for MEDLINE]
14.

The fetal basis of amyloidogenesis: exposure to lead and latent overexpression of amyloid precursor protein and beta-amyloid in the aging brain.

Basha MR, Wei W, Bakheet SA, Benitez N, Siddiqi HK, Ge YW, Lahiri DK, Zawia NH.

J Neurosci. 2005 Jan 26;25(4):823-9.

PMID:
15673661
[PubMed - indexed for MEDLINE]
Free Article
15.

Role of cyclin-dependent kinase 5 in the neurodegenerative process triggered by amyloid-Beta and prion peptides: implications for Alzheimer's disease and prion-related encephalopathies.

Lopes JP, Oliveira CR, Agostinho P.

Cell Mol Neurobiol. 2007 Nov;27(7):943-57. Epub 2007 Oct 27.

PMID:
17965932
[PubMed - indexed for MEDLINE]
16.

Alzheimer's disease biomarkers and epigenetic intermediates following exposure to Pb in vitro.

Bihaqi SW, Zawia NH.

Curr Alzheimer Res. 2012 Jun;9(5):555-62.

PMID:
22272629
[PubMed - indexed for MEDLINE]
17.

Alzheimer's disease.

De-Paula VJ, Radanovic M, Diniz BS, Forlenza OV.

Subcell Biochem. 2012;65:329-52. doi: 10.1007/978-94-007-5416-4_14. Review.

PMID:
23225010
[PubMed - indexed for MEDLINE]
18.

AbetaPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576.

Otth C, Concha II, Arendt T, Stieler J, Schliebs R, González-Billault C, Maccioni RB.

J Alzheimers Dis. 2002 Oct;4(5):417-30.

PMID:
12446973
[PubMed - indexed for MEDLINE]
19.

Cerebrolysin decreases amyloid-beta production by regulating amyloid protein precursor maturation in a transgenic model of Alzheimer's disease.

Rockenstein E, Torrance M, Mante M, Adame A, Paulino A, Rose JB, Crews L, Moessler H, Masliah E.

J Neurosci Res. 2006 May 15;83(7):1252-61.

PMID:
16511867
[PubMed - indexed for MEDLINE]
20.

Endogenous conversion of omega-6 into omega-3 fatty acids improves neuropathology in an animal model of Alzheimer's disease.

Lebbadi M, Julien C, Phivilay A, Tremblay C, Emond V, Kang JX, Calon F.

J Alzheimers Dis. 2011;27(4):853-69. doi: 10.3233/JAD-2011-111010.

PMID:
21914946
[PubMed - indexed for MEDLINE]

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