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Results: 1 to 20 of 141

1.

Two β-strands of RAGE participate in the recognition and transport of amyloid-β peptide across the blood brain barrier.

Kim SJ, Ahn JW, Kim H, Ha HJ, Lee SW, Kim HK, Lee S, Hong HS, Kim YH, Choi CY.

Biochem Biophys Res Commun. 2013 Sep 20;439(2):252-7. doi: 10.1016/j.bbrc.2013.08.047. Epub 2013 Aug 23.

PMID:
23973487
[PubMed - indexed for MEDLINE]
2.

Aβ1-42 reduces P-glycoprotein in the blood-brain barrier through RAGE-NF-κB signaling.

Park R, Kook SY, Park JC, Mook-Jung I.

Cell Death Dis. 2014 Jun 26;5:e1299. doi: 10.1038/cddis.2014.258.

PMID:
24967961
[PubMed - indexed for MEDLINE]
3.

Aβ₁₋₄₂-RAGE interaction disrupts tight junctions of the blood-brain barrier via Ca²⁺-calcineurin signaling.

Kook SY, Hong HS, Moon M, Ha CM, Chang S, Mook-Jung I.

J Neurosci. 2012 Jun 27;32(26):8845-54. doi: 10.1523/JNEUROSCI.6102-11.2012.

PMID:
22745485
[PubMed - indexed for MEDLINE]
Free Article
4.

Epitope-dependent effects of Beta-amyloid antibodies on Beta-amyloid clearance in an in vitro model of the blood-brain barrier.

Bachmeier CJ, Beaulieu-Abdelahad D, Mullan MJ, Paris D.

Microcirculation. 2011 Jul;18(5):373-9. doi: 10.1111/j.1549-8719.2011.00096.x.

PMID:
21418385
[PubMed - indexed for MEDLINE]
5.

Clearance of amyloid-beta peptide across the blood-brain barrier: implication for therapies in Alzheimer's disease.

Deane R, Bell RD, Sagare A, Zlokovic BV.

CNS Neurol Disord Drug Targets. 2009 Mar;8(1):16-30. Review.

PMID:
19275634
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model.

Cho HJ, Son SM, Jin SM, Hong HS, Shin DH, Kim SJ, Huh K, Mook-Jung I.

FASEB J. 2009 Aug;23(8):2639-49. doi: 10.1096/fj.08-126383. Epub 2009 Mar 30.

PMID:
19332646
[PubMed - indexed for MEDLINE]
Free Article
7.

Is RAGE still a therapeutic target for Alzheimer's disease?

Deane RJ.

Future Med Chem. 2012 May;4(7):915-25. doi: 10.4155/fmc.12.51. Review.

PMID:
22571615
[PubMed - indexed for MEDLINE]
8.

A multimodal RAGE-specific inhibitor reduces amyloid β-mediated brain disorder in a mouse model of Alzheimer disease.

Deane R, Singh I, Sagare AP, Bell RD, Ross NT, LaRue B, Love R, Perry S, Paquette N, Deane RJ, Thiyagarajan M, Zarcone T, Fritz G, Friedman AE, Miller BL, Zlokovic BV.

J Clin Invest. 2012 Apr;122(4):1377-92. doi: 10.1172/JCI58642. Epub 2012 Mar 12.

PMID:
22406537
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Hypertension induces brain β-amyloid accumulation, cognitive impairment, and memory deterioration through activation of receptor for advanced glycation end products in brain vasculature.

Carnevale D, Mascio G, D'Andrea I, Fardella V, Bell RD, Branchi I, Pallante F, Zlokovic B, Yan SS, Lembo G.

Hypertension. 2012 Jul;60(1):188-97. doi: 10.1161/HYPERTENSIONAHA.112.195511. Epub 2012 May 21.

PMID:
22615109
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation?

Yan SD, Bierhaus A, Nawroth PP, Stern DM.

J Alzheimers Dis. 2009;16(4):833-43. doi: 10.3233/JAD-2009-1030. Review.

PMID:
19387116
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Preventing activation of receptor for advanced glycation endproducts in Alzheimer's disease.

Lue LF, Yan SD, Stern DM, Walker DG.

Curr Drug Targets CNS Neurol Disord. 2005 Jun;4(3):249-66. Review.

PMID:
15975028
[PubMed - indexed for MEDLINE]
12.

RAGE does not affect amyloid pathology in transgenic ArcAbeta mice.

Vodopivec I, Galichet A, Knobloch M, Bierhaus A, Heizmann CW, Nitsch RM.

Neurodegener Dis. 2009;6(5-6):270-80. doi: 10.1159/000261723. Epub 2010 Feb 10.

PMID:
20145420
[PubMed - indexed for MEDLINE]
13.

RAGE and amyloid beta interactions: atomic force microscopy and molecular modeling.

Chaney MO, Stine WB, Kokjohn TA, Kuo YM, Esh C, Rahman A, Luehrs DC, Schmidt AM, Stern D, Yan SD, Roher AE.

Biochim Biophys Acta. 2005 Jun 30;1741(1-2):199-205. Epub 2005 Apr 19.

PMID:
15882940
[PubMed - indexed for MEDLINE]
Free Article
14.

Fusion antibody for Alzheimer's disease with bidirectional transport across the blood-brain barrier and abeta fibril disaggregation.

Boado RJ, Zhang Y, Zhang Y, Xia CF, Pardridge WM.

Bioconjug Chem. 2007 Mar-Apr;18(2):447-55. Epub 2007 Feb 22.

PMID:
17315944
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

RAGE: a potential target for Abeta-mediated cellular perturbation in Alzheimer's disease.

Chen X, Walker DG, Schmidt AM, Arancio O, Lue LF, Yan SD.

Curr Mol Med. 2007 Dec;7(8):735-42. Review.

PMID:
18331231
[PubMed - indexed for MEDLINE]
16.

Regulated proteolysis of RAGE and AbetaPP as possible link between type 2 diabetes mellitus and Alzheimer's disease.

Kojro E, Postina R.

J Alzheimers Dis. 2009;16(4):865-78. doi: 10.3233/JAD-2009-0998. Review.

PMID:
19387119
[PubMed - indexed for MEDLINE]
17.

Site-specific blockade of RAGE-Vd prevents amyloid-beta oligomer neurotoxicity.

Sturchler E, Galichet A, Weibel M, Leclerc E, Heizmann CW.

J Neurosci. 2008 May 14;28(20):5149-58. doi: 10.1523/JNEUROSCI.4878-07.2008.

PMID:
18480271
[PubMed - indexed for MEDLINE]
Free Article
18.

Crosstalk between calcium, amyloid beta and the receptor for advanced glycation endproducts in Alzheimer's disease.

Leclerc E, Sturchler E, Vetter SW, Heizmann CW.

Rev Neurosci. 2009;20(2):95-110. Review.

PMID:
19774788
[PubMed - indexed for MEDLINE]
19.

RAGE (yin) versus LRP (yang) balance regulates alzheimer amyloid beta-peptide clearance through transport across the blood-brain barrier.

Deane R, Wu Z, Zlokovic BV.

Stroke. 2004 Nov;35(11 Suppl 1):2628-31. Epub 2004 Sep 30.

PMID:
15459432
[PubMed - indexed for MEDLINE]
Free Article
20.

Immunodistribution of amyloid beta protein (Aβ) and advanced glycation end-product receptors (RAGE) in choroid plexus and ependyma of resuscitated patients.

Maślińska D, Laure-Kamionowska M, Taraszewska A, Deręgowski K, Maśliński S.

Folia Neuropathol. 2011;49(4):295-300.

PMID:
22212919
[PubMed - indexed for MEDLINE]
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