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Results: 1 to 20 of 129

1.

Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease.

Tsujimoto M, Nagano Y, Hosoda S, Shiraishi A, Miyoshi A, Hiraoka S, Furukubo T, Izumi S, Yamakawa T, Minegaki T, Nishiguchi K.

Toxins (Basel). 2013 Aug 19;5(8):1475-85. doi: 10.3390/toxins5081475.

PMID:
23965431
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A furan fatty acid and indoxyl sulfate are the putative inhibitors of thyroxine hepatocyte transport in uremia.

Lim CF, Bernard BF, de Jong M, Docter R, Krenning EP, Hennemann G.

J Clin Endocrinol Metab. 1993 Feb;76(2):318-24.

PMID:
8432774
[PubMed - indexed for MEDLINE]
3.

Influence of serum in hemodialysis patients on the expression of intestinal and hepatic transporters for the excretion of pravastatin.

Tsujimoto M, Hatozaki D, Shima D, Yokota H, Furukubo T, Izumi S, Yamakawa T, Minegaki T, Nishiguchi K.

Ther Apher Dial. 2012 Dec;16(6):580-7. doi: 10.1111/j.1744-9987.2012.01100.x. Epub 2012 Aug 29.

PMID:
23190519
[PubMed - indexed for MEDLINE]
4.

Effect of uremic serum and uremic toxins on drug metabolism in human microsomes.

Volpe DA, Tobin GA, Tavakkoli F, Dowling TC, Light PD, Parker RJ.

Regul Toxicol Pharmacol. 2014 Mar;68(2):297-303. doi: 10.1016/j.yrtph.2013.10.006. Epub 2013 Oct 30.

PMID:
24184159
[PubMed - indexed for MEDLINE]
5.

Possibility of decrease in CYP1A2 function in patients with end-stage renal disease.

Tsujimoto M, Sugimoto S, Nagatomo M, Furukubo T, Izumi S, Yamakawa T, Minegaki T, Nishiguchi K.

Ther Apher Dial. 2014 Apr;18(2):174-80. doi: 10.1111/1744-9987.12100. Epub 2013 Sep 30.

PMID:
24119207
[PubMed - indexed for MEDLINE]
6.

Does the adequacy parameter Kt/V(urea) reflect uremic toxin concentrations in hemodialysis patients?

Eloot S, Van Biesen W, Glorieux G, Neirynck N, Dhondt A, Vanholder R.

PLoS One. 2013 Nov 13;8(11):e76838. doi: 10.1371/journal.pone.0076838. eCollection 2013.

PMID:
24236005
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Effects of uremic serum and uremic toxins on hepatic uptake of digoxin.

Tsujimoto M, Kinoshita Y, Hirata S, Otagiri M, Ohtani H, Sawada Y.

Ther Drug Monit. 2008 Oct;30(5):576-82. doi: 10.1097/FTD.0b013e3181838077.

PMID:
18708994
[PubMed - indexed for MEDLINE]
8.

CYP3A4 is a human microsomal vitamin D 25-hydroxylase.

Gupta RP, Hollis BW, Patel SB, Patrick KS, Bell NH.

J Bone Miner Res. 2004 Apr;19(4):680-8. Epub 2003 Dec 22.

PMID:
15005856
[PubMed - indexed for MEDLINE]
9.

Hepatic clearance, but not gut availability, of erythromycin is altered in patients with end-stage renal disease.

Sun H, Frassetto LA, Huang Y, Benet LZ.

Clin Pharmacol Ther. 2010 Apr;87(4):465-72. doi: 10.1038/clpt.2009.247. Epub 2010 Jan 20.

PMID:
20090676
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Effects of uremic toxins on hepatic uptake and metabolism of erythromycin.

Sun H, Huang Y, Frassetto L, Benet LZ.

Drug Metab Dispos. 2004 Nov;32(11):1239-46. Epub 2004 Jul 30.

PMID:
15286055
[PubMed - indexed for MEDLINE]
Free Article
11.

Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells.

Fukumori S, Murata T, Taguchi M, Hashimoto Y.

Drug Metab Pharmacokinet. 2007 Oct;22(5):377-81.

PMID:
17965521
[PubMed - indexed for MEDLINE]
Free Article
12.

Human cytochrome P450-dependent differential metabolism among three 2α-substituted-1α,25-dihydroxyvitamin D(3) analogs.

Yasuda K, Ikushiro S, Kamakura M, Takano M, Saito N, Kittaka A, Chen TC, Ohta M, Sakaki T.

J Steroid Biochem Mol Biol. 2013 Jan;133:84-92. doi: 10.1016/j.jsbmb.2012.09.006. Epub 2012 Sep 13.

PMID:
22982757
[PubMed - indexed for MEDLINE]
13.

A novel UPLC-MS-MS method for simultaneous determination of seven uremic retention toxins with cardiovascular relevance in chronic kidney disease patients.

Boelaert J, Lynen F, Glorieux G, Eloot S, Van Landschoot M, Waterloos MA, Sandra P, Vanholder R.

Anal Bioanal Chem. 2013 Feb;405(6):1937-47. doi: 10.1007/s00216-012-6636-9. Epub 2013 Jan 11.

PMID:
23307120
[PubMed - indexed for MEDLINE]
14.

Establishment of a stable human cell line, HPL-A3, for use in reporter gene assays of cytochrome P450 3A inducers.

Sekimoto M, Sano S, Hosaka T, Nemoto K, Degawa M.

Biol Pharm Bull. 2012;35(5):677-85.

PMID:
22687401
[PubMed - indexed for MEDLINE]
Free Article
15.

Decreased bilirubin-binding capacity in uremic serum caused by an accumulation of furan dicarboxylic acid.

Tsutsumi Y, Maruyama T, Takadate A, Shimada H, Otagiri M.

Nephron. 2000 May;85(1):60-4.

PMID:
10773757
[PubMed - indexed for MEDLINE]
16.

A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4.

Ma X, Cheung C, Krausz KW, Shah YM, Wang T, Idle JR, Gonzalez FJ.

Drug Metab Dispos. 2008 Dec;36(12):2506-12. doi: 10.1124/dmd.108.022723. Epub 2008 Sep 17.

PMID:
18799805
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Major role of organic anion transporter 3 in the transport of indoxyl sulfate in the kidney.

Deguchi T, Ohtsuki S, Otagiri M, Takanaga H, Asaba H, Mori S, Terasaki T.

Kidney Int. 2002 May;61(5):1760-8.

PMID:
11967025
[PubMed - indexed for MEDLINE]
Free Article
19.

Involvement of promoter methylation in the regulation of Pregnane X receptor in colon cancer cells.

Habano W, Gamo T, Terashima J, Sugai T, Otsuka K, Wakabayashi G, Ozawa S.

BMC Cancer. 2011 Feb 22;11:81. doi: 10.1186/1471-2407-11-81.

PMID:
21342487
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Uremic toxins overload accelerates renal damage in a rat model of chronic renal failure.

Satoh M, Hayashi H, Watanabe M, Ueda K, Yamato H, Yoshioka T, Motojima M.

Nephron Exp Nephrol. 2003;95(3):e111-8.

PMID:
14646363
[PubMed - indexed for MEDLINE]
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