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Results: 1 to 20 of 100

1.

p53 deficiency enhances mitotic arrest and slippage induced by pharmacological inhibition of Aurora kinases.

Marxer M, Ma HT, Man WY, Poon RY.

Oncogene. 2014 Jul 3;33(27):3550-60. doi: 10.1038/onc.2013.325. Epub 2013 Aug 19.

PMID:
23955083
[PubMed - in process]
2.

Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.

den Hollander J, Rimpi S, Doherty JR, Rudelius M, Buck A, Hoellein A, Kremer M, Graf N, Scheerer M, Hall MA, Goga A, von Bubnoff N, Duyster J, Peschel C, Cleveland JL, Nilsson JA, Keller U.

Blood. 2010 Sep 2;116(9):1498-505. doi: 10.1182/blood-2009-11-251074. Epub 2010 Jun 2.

PMID:
20519624
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Determinants for the efficiency of anticancer drugs targeting either Aurora-A or Aurora-B kinases in human colon carcinoma cells.

Kaestner P, Stolz A, Bastians H.

Mol Cancer Ther. 2009 Jul;8(7):2046-56. doi: 10.1158/1535-7163.MCT-09-0323. Epub 2009 Jul 7.

PMID:
19584233
[PubMed - indexed for MEDLINE]
Free Article
4.

The inhibition of Aurora A abrogates the mitotic delay induced by microtubule perturbing agents.

Wysong DR, Chakravarty A, Hoar K, Ecsedy JA.

Cell Cycle. 2009 Mar 15;8(6):876-88. Epub 2009 Mar 21.

PMID:
19221504
[PubMed - indexed for MEDLINE]
Free Article
5.

Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells.

Zou Z, Yuan Z, Zhang Q, Long Z, Chen J, Tang Z, Zhu Y, Chen S, Xu J, Yan M, Wang J, Liu Q.

Autophagy. 2012 Dec;8(12):1798-810. doi: 10.4161/auto.22110. Epub 2012 Oct 1.

PMID:
23026799
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Preferential killing of p53-deficient cancer cells by reversine.

Jemaà M, Galluzzi L, Kepp O, Boilève A, Lissa D, Senovilla L, Harper F, Pierron G, Berardinelli F, Antoccia A, Castedo M, Vitale I, Kroemer G.

Cell Cycle. 2012 Jun 1;11(11):2149-58. doi: 10.4161/cc.20621. Epub 2012 Jun 1.

PMID:
22592527
[PubMed - indexed for MEDLINE]
7.

Validating Aurora B as an anti-cancer drug target.

Girdler F, Gascoigne KE, Eyers PA, Hartmuth S, Crafter C, Foote KM, Keen NJ, Taylor SS.

J Cell Sci. 2006 Sep 1;119(Pt 17):3664-75. Epub 2006 Aug 15.

PMID:
16912073
[PubMed - indexed for MEDLINE]
Free Article
8.

Aurora kinase inhibition induces PUMA via NF-κB to kill colon cancer cells.

Sun J, Knickelbein K, He K, Chen D, Dudgeon C, Shu Y, Yu J, Zhang L.

Mol Cancer Ther. 2014 May;13(5):1298-308. doi: 10.1158/1535-7163.MCT-13-0846. Epub 2014 Feb 21.

PMID:
24563542
[PubMed - in process]
9.

The aurora kinases in cell cycle and leukemia.

Goldenson B, Crispino JD.

Oncogene. 2014 Mar 17. doi: 10.1038/onc.2014.14. [Epub ahead of print]

PMID:
24632603
[PubMed - as supplied by publisher]
10.

Bub1 and aurora B cooperate to maintain BubR1-mediated inhibition of APC/CCdc20.

Morrow CJ, Tighe A, Johnson VL, Scott MI, Ditchfield C, Taylor SS.

J Cell Sci. 2005 Aug 15;118(Pt 16):3639-52. Epub 2005 Jul 26.

PMID:
16046481
[PubMed - indexed for MEDLINE]
Free Article
11.

Aurora kinase A mediates epithelial ovarian cancer cell migration and adhesion.

Do TV, Xiao F, Bickel LE, Klein-Szanto AJ, Pathak HB, Hua X, Howe C, O'Brien SW, Maglaty M, Ecsedy JA, Litwin S, Golemis EA, Schilder RJ, Godwin AK, Connolly DC.

Oncogene. 2014 Jan 30;33(5):539-49. doi: 10.1038/onc.2012.632. Epub 2013 Jan 21.

PMID:
23334327
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

The induction of polyploidy or apoptosis by the Aurora A kinase inhibitor MK8745 is p53-dependent.

Nair JS, Ho AL, Schwartz GK.

Cell Cycle. 2012 Feb 15;11(4):807-17. doi: 10.4161/cc.11.4.19323. Epub 2012 Feb 15.

PMID:
22293494
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

Depletion of Aurora-A in zebrafish causes growth retardation due to mitotic delay and p53-dependent cell death.

Jeon HY, Lee H.

FEBS J. 2013 Mar;280(6):1518-30. doi: 10.1111/febs.12153. Epub 2013 Feb 24.

PMID:
23351126
[PubMed - indexed for MEDLINE]
15.

Inhibition of the aurora kinases suppresses in vitro NT2-D1 cell growth and tumorigenicity.

Ulisse S, Arlot-Bonnemains Y, Baldini E, Morrone S, Carocci S, Di Luigi L, D'Armiento M.

J Endocrinol. 2010 Feb;204(2):135-42. doi: 10.1677/JOE-09-0257. Epub 2009 Nov 4.

PMID:
19889886
[PubMed - indexed for MEDLINE]
Free Article
16.

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores.

Ditchfield C, Johnson VL, Tighe A, Ellston R, Haworth C, Johnson T, Mortlock A, Keen N, Taylor SS.

J Cell Biol. 2003 Apr 28;161(2):267-80.

PMID:
12719470
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Salt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death.

Chen H, Huang S, Han X, Zhang J, Shan C, Tsang YH, Ma HT, Poon RY.

Cell Death Dis. 2014 Apr 17;5:e1177. doi: 10.1038/cddis.2014.154.

PMID:
24743732
[PubMed - in process]
Free PMC Article
18.

Spindle assembly checkpoint gene expression in childhood adrenocortical tumors (ACT): Overexpression of Aurora kinases A and B is associated with a poor prognosis.

Borges KS, Moreno DA, Martinelli CE Jr, Antonini SR, de Castro M, Tucci S Jr, Neder L, Ramalho LN, Seidinger AL, Cardinalli I, Mastellaro MJ, Yunes JA, Brandalise SR, Tone LG, Scrideli CA.

Pediatr Blood Cancer. 2013 Nov;60(11):1809-16. doi: 10.1002/pbc.24653. Epub 2013 Jun 20.

PMID:
23788275
[PubMed - indexed for MEDLINE]
19.

Tetraploidization increases sensitivity to Aurora B kinase inhibition.

Marxer M, Foucar CE, Man WY, Chen Y, Ma HT, Poon RY.

Cell Cycle. 2012 Jul 1;11(13):2567-77. doi: 10.4161/cc.20947. Epub 2012 Jul 1.

PMID:
22722494
[PubMed - indexed for MEDLINE]
20.

VX-680 inhibits Aurora A and Aurora B kinase activity in human cells.

Tyler RK, Shpiro N, Marquez R, Eyers PA.

Cell Cycle. 2007 Nov 15;6(22):2846-54. Epub 2007 Aug 27.

PMID:
18032922
[PubMed - indexed for MEDLINE]
Free Article

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