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Results: 1 to 20 of 95

1.

Protons as second messenger regulators of G protein signaling.

Isom DG, Sridharan V, Baker R, Clement ST, Smalley DM, Dohlman HG.

Mol Cell. 2013 Aug 22;51(4):531-8. doi: 10.1016/j.molcel.2013.07.012. Epub 2013 Aug 15.

PMID:
23954348
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

An acid test for g proteins.

Sprang SR.

Mol Cell. 2013 Aug 22;51(4):405-6. doi: 10.1016/j.molcel.2013.08.012.

PMID:
23973370
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Detection of G protein-selective G protein-coupled receptor (GPCR) conformations in live cells.

Malik RU, Ritt M, DeVree BT, Neubig RR, Sunahara RK, Sivaramakrishnan S.

J Biol Chem. 2013 Jun 14;288(24):17167-78. doi: 10.1074/jbc.M113.464065. Epub 2013 Apr 29.

PMID:
23629648
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Cell signalling: Responding to intracellular pH.

Minton K.

Nat Rev Mol Cell Biol. 2013 Oct;14(10):608. doi: 10.1038/nrm3669. No abstract available.

PMID:
24061222
[PubMed - indexed for MEDLINE]
5.

Fusion proteins as model systems for the analysis of constitutive GPCR activity.

Schneider EH, Seifert R.

Methods Enzymol. 2010;485:459-80. doi: 10.1016/B978-0-12-381296-4.00025-7.

PMID:
21050932
[PubMed - indexed for MEDLINE]
6.

Receptor-mediated changes at the myristoylated amino terminus of Galpha(il) proteins.

Preininger AM, Parello J, Meier SM, Liao G, Hamm HE.

Biochemistry. 2008 Sep 30;47(39):10281-93. doi: 10.1021/bi800741r. Epub 2008 Sep 5.

PMID:
18771287
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Identification of a novel site within G protein alpha subunits important for specificity of receptor-G protein interaction.

Heydorn A, Ward RJ, Jorgensen R, Rosenkilde MM, Frimurer TM, Milligan G, Kostenis E.

Mol Pharmacol. 2004 Aug;66(2):250-9.

PMID:
15266015
[PubMed - indexed for MEDLINE]
Free Article
8.

G proteins in reverse mode: receptor-mediated GTP release inhibits G protein and effector function.

Hommers LG, Klenk C, Dees C, Bünemann M.

J Biol Chem. 2010 Mar 12;285(11):8227-33. doi: 10.1074/jbc.M109.015388. Epub 2010 Jan 14.

PMID:
20075078
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A highly conserved glycine within linker I and the extreme C terminus of G protein alpha subunits interact cooperatively in switching G protein-coupled receptor-to-effector specificity.

Kostenis E, Martini L, Ellis J, Waldhoer M, Heydorn A, Rosenkilde MM, Norregaard PK, Jorgensen R, Whistler JL, Milligan G.

J Pharmacol Exp Ther. 2005 Apr;313(1):78-87. Epub 2004 Dec 22.

PMID:
15615862
[PubMed - indexed for MEDLINE]
Free Article
10.

Regulators of G-protein signaling and their Gα substrates: promises and challenges in their use as drug discovery targets.

Kimple AJ, Bosch DE, Giguère PM, Siderovski DP.

Pharmacol Rev. 2011 Sep;63(3):728-49. doi: 10.1124/pr.110.003038. Epub 2011 Jul 7. Review.

PMID:
21737532
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Analysis of G-protein-coupled receptor kinase RGS homology domains.

Day PW, Wedegaertner PB, Benovic JL.

Methods Enzymol. 2004;390:295-310.

PMID:
15488185
[PubMed - indexed for MEDLINE]
12.

Endogenous regulators of G protein signaling differentially modulate full and partial mu-opioid agonists at adenylyl cyclase as predicted by a collision coupling model.

Clark MJ, Linderman JJ, Traynor JR.

Mol Pharmacol. 2008 May;73(5):1538-48. doi: 10.1124/mol.107.043547. Epub 2008 Feb 19.

PMID:
18285510
[PubMed - indexed for MEDLINE]
Free Article
13.

The GAPs, GEFs, and GDIs of heterotrimeric G-protein alpha subunits.

Siderovski DP, Willard FS.

Int J Biol Sci. 2005;1(2):51-66. Epub 2005 Apr 1. Review.

PMID:
15951850
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Rapid irreversible G protein alpha subunit misfolding due to intramolecular kinetic bottleneck that precedes Mg2+ "lock" after GTP/GDP exchange.

Zelent B, Veklich Y, Murray J, Parkes JH, Gibson S, Liebman PA.

Biochemistry. 2001 Aug 14;40(32):9647-56.

PMID:
11583165
[PubMed - indexed for MEDLINE]
15.

Different domains in the third intracellular loop of the GLP-1 receptor are responsible for Galpha(s) and Galpha(i)/Galpha(o) activation.

Hällbrink M, Holmqvist T, Olsson M, Ostenson CG, Efendic S, Langel U.

Biochim Biophys Acta. 2001 Mar 9;1546(1):79-86.

PMID:
11257510
[PubMed - indexed for MEDLINE]
16.

Characterization of constitutively active mutants of G protein-coupled receptors.

Navenot JM, Wang ZX, Peiper SC.

Methods Mol Biol. 2006;332:129-39.

PMID:
16878689
[PubMed - indexed for MEDLINE]
17.

Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain.

Mannoury la Cour C, El Mestikawy S, Hanoun N, Hamon M, Lanfumey L.

Mol Pharmacol. 2006 Sep;70(3):1013-21. Epub 2006 Jun 13.

PMID:
16772521
[PubMed - indexed for MEDLINE]
Free Article
18.

Regulatory interaction of the Galpha protein with phospholipase A2 in the plasma membrane of Eschscholzia californica.

Heinze M, Steighardt J, Gesell A, Schwartze W, Roos W.

Plant J. 2007 Dec;52(6):1041-51. Epub 2007 Oct 3.

PMID:
17916111
[PubMed - indexed for MEDLINE]
19.

Molecular dissection of G protein preference using Gsalpha chimeras reveals novel ligand signaling of GPCRs.

Hsu SH, Luo CW.

Am J Physiol Endocrinol Metab. 2007 Oct;293(4):E1021-9. Epub 2007 Jul 24.

PMID:
17652154
[PubMed - indexed for MEDLINE]
Free Article
20.

Signaling through G protein coupled receptors.

Tuteja N.

Plant Signal Behav. 2009 Oct;4(10):942-7. Epub 2009 Oct 14. Review.

PMID:
19826234
[PubMed - indexed for MEDLINE]
Free PMC Article

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