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Results: 1 to 20 of 117

1.

A novel application of furazolidone: anti-leukemic activity in acute myeloid leukemia.

Jiang X, Sun L, Qiu JJ, Sun X, Li S, Wang X, So CW, Dong S.

PLoS One. 2013 Aug 9;8(8):e72335. doi: 10.1371/journal.pone.0072335. eCollection 2013.

PMID:
23951311
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Inhibition of the LSD1 (KDM1A) demethylase reactivates the all-trans-retinoic acid differentiation pathway in acute myeloid leukemia.

Schenk T, Chen WC, Göllner S, Howell L, Jin L, Hebestreit K, Klein HU, Popescu AC, Burnett A, Mills K, Casero RA Jr, Marton L, Woster P, Minden MD, Dugas M, Wang JC, Dick JE, Müller-Tidow C, Petrie K, Zelent A.

Nat Med. 2012 Mar 11;18(4):605-11. doi: 10.1038/nm.2661.

PMID:
22406747
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

MN1 overexpression induces acute myeloid leukemia in mice and predicts ATRA resistance in patients with AML.

Heuser M, Argiropoulos B, Kuchenbauer F, Yung E, Piper J, Fung S, Schlenk RF, Dohner K, Hinrichsen T, Rudolph C, Schambach A, Baum C, Schlegelberger B, Dohner H, Ganser A, Humphries RK.

Blood. 2007 Sep 1;110(5):1639-47. Epub 2007 May 9.

PMID:
17494859
[PubMed - indexed for MEDLINE]
Free Article
4.

ATRA resolves the differentiation block in t(15;17) acute myeloid leukemia by restoring PU.1 expression.

Mueller BU, Pabst T, Fos J, Petkovic V, Fey MF, Asou N, Buergi U, Tenen DG.

Blood. 2006 Apr 15;107(8):3330-8. Epub 2005 Dec 13.

PMID:
16352814
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Targeting AML1/ETO-histone deacetylase repressor complex: a novel mechanism for valproic acid-mediated gene expression and cellular differentiation in AML1/ETO-positive acute myeloid leukemia cells.

Liu S, Klisovic RB, Vukosavljevic T, Yu J, Paschka P, Huynh L, Pang J, Neviani P, Liu Z, Blum W, Chan KK, Perrotti D, Marcucci G.

J Pharmacol Exp Ther. 2007 Jun;321(3):953-60. Epub 2007 Mar 26.

PMID:
17389244
[PubMed - indexed for MEDLINE]
Free Article
6.

[Immunophenotypic features of acute myeloid leukemia with AML-1/ETO fusion gene].

Zhang JJ, DU X, Huang ZX, Su JH, Zhou MH.

Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2007 Apr;15(2):378-81. Chinese.

PMID:
17493351
[PubMed - indexed for MEDLINE]
7.

Synergistic cytotoxic activity of recombinant TRAIL plus the non-genotoxic activator of the p53 pathway nutlin-3 in acute myeloid leukemia cells.

Secchiero P, Zerbinati C, di Iasio MG, Melloni E, Tiribelli M, Grill V, Zauli G.

Curr Drug Metab. 2007 May;8(4):395-403.

PMID:
17504227
[PubMed - indexed for MEDLINE]
8.

TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.

Riccioni R, Pasquini L, Mariani G, Saulle E, Rossini A, Diverio D, Pelosi E, Vitale A, Chierichini A, Cedrone M, Foà R, Lo Coco F, Peschle C, Testa U.

Haematologica. 2005 May;90(5):612-24.

PMID:
15921376
[PubMed - indexed for MEDLINE]
Free Article
9.

Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically.

Zapotocky M, Mejstrikova E, Smetana K, Stary J, Trka J, Starkova J.

Cancer Lett. 2012 Jun 28;319(2):144-53. doi: 10.1016/j.canlet.2011.12.041. Epub 2012 Jan 17.

PMID:
22261333
[PubMed - indexed for MEDLINE]
10.

Functional G-CSF pathways in t(8;21) leukemic cells allow for differentiation induction and degradation of AML1-ETO.

Da Silva N, Meyer-Monard S, Menot ML, Parrado A, Lebel A, Balitrand N, Fenaux P, Micléa JM, Rousselot P, Degos L, Dombret H, Chomienne C.

Hematol J. 2000;1(5):316-28.

PMID:
11920209
[PubMed - indexed for MEDLINE]
11.

Novel triterpenoid CDDO-Me is a potent inducer of apoptosis and differentiation in acute myelogenous leukemia.

Konopleva M, Tsao T, Ruvolo P, Stiouf I, Estrov Z, Leysath CE, Zhao S, Harris D, Chang S, Jackson CE, Munsell M, Suh N, Gribble G, Honda T, May WS, Sporn MB, Andreeff M.

Blood. 2002 Jan 1;99(1):326-35.

PMID:
11756188
[PubMed - indexed for MEDLINE]
Free Article
12.

A histone acetyltransferase p300 inhibitor C646 induces cell cycle arrest and apoptosis selectively in AML1-ETO-positive AML cells.

Gao XN, Lin J, Ning QY, Gao L, Yao YS, Zhou JH, Li YH, Wang LL, Yu L.

PLoS One. 2013;8(2):e55481. doi: 10.1371/journal.pone.0055481. Epub 2013 Feb 4.

PMID:
23390536
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Preclinical activity of a novel CRM1 inhibitor in acute myeloid leukemia.

Ranganathan P, Yu X, Na C, Santhanam R, Shacham S, Kauffman M, Walker A, Klisovic R, Blum W, Caligiuri M, Croce CM, Marcucci G, Garzon R.

Blood. 2012 Aug 30;120(9):1765-73. doi: 10.1182/blood-2012-04-423160. Epub 2012 Jun 7.

PMID:
22677130
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Curcumin reduces expression of Bcl-2, leading to apoptosis in daunorubicin-insensitive CD34+ acute myeloid leukemia cell lines and primary sorted CD34+ acute myeloid leukemia cells.

Rao J, Xu DR, Zheng FM, Long ZJ, Huang SS, Wu X, Zhou WH, Huang RW, Liu Q.

J Transl Med. 2011 May 19;9:71. doi: 10.1186/1479-5876-9-71.

PMID:
21595920
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Pharicin B stabilizes retinoic acid receptor-α and presents synergistic differentiation induction with ATRA in myeloid leukemic cells.

Gu ZM, Wu YL, Zhou MY, Liu CX, Xu HZ, Yan H, Zhao Y, Huang Y, Sun HD, Chen GQ.

Blood. 2010 Dec 9;116(24):5289-97. doi: 10.1182/blood-2010-02-267963. Epub 2010 Aug 25.

PMID:
20739655
[PubMed - indexed for MEDLINE]
Free Article
16.

PC-SPES decreases proliferation and induces differentiation and apoptosis of human acute myeloid leukemia cells.

Ikezoe T, Chen S, Saito T, Asou H, Kyo T, Tanosaki S, Heber D, Taguchi H, Koeffler HP.

Int J Oncol. 2003 Oct;23(4):1203-11.

PMID:
12964005
[PubMed - indexed for MEDLINE]
17.

AML1-ETO rapidly induces acute myeloblastic leukemia in cooperation with the Wilms tumor gene, WT1.

Nishida S, Hosen N, Shirakata T, Kanato K, Yanagihara M, Nakatsuka S, Hoshida Y, Nakazawa T, Harada Y, Tatsumi N, Tsuboi A, Kawakami M, Oka Y, Oji Y, Aozasa K, Kawase I, Sugiyama H.

Blood. 2006 Apr 15;107(8):3303-12. Epub 2005 Dec 27.

PMID:
16380455
[PubMed - indexed for MEDLINE]
Free Article
18.

p38αMAPK interacts with and inhibits RARα: suppression of the kinase enhances the therapeutic activity of retinoids in acute myeloid leukemia cells.

Gianni M, Peviani M, Bruck N, Rambaldi A, Borleri G, Terao M, Kurosaki M, Paroni G, Rochette-Egly C, Garattini E.

Leukemia. 2012 Aug;26(8):1850-61. doi: 10.1038/leu.2012.50. Epub 2012 Feb 22.

PMID:
22354283
[PubMed - indexed for MEDLINE]
19.

[ITF-2357 on inhibition myeloid leukemic cell lines cells proliferation in vitro and its mechanism].

Yu WJ, Wang L, You LS, Mei C, Ma QL, Jin J.

Zhonghua Xue Ye Xue Za Zhi. 2012 May;33(5):366-70. Chinese.

PMID:
22781793
[PubMed - indexed for MEDLINE]
Free Article
20.

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