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Contribution of 32 GWAS-identified common variants to severe obesity in European adults referred for bariatric surgery.

Mägi R, Manning S, Yousseif A, Pucci A, Santini F, Karra E, Querci G, Pelosini C, McCarthy MI, Lindgren CM, Batterham RL.

PLoS One. 2013 Aug 7;8(8):e70735. doi: 10.1371/journal.pone.0070735. eCollection 2013.


Analysis of the contribution of FTO, NPC1, ENPP1, NEGR1, GNPDA2 and MC4R genes to obesity in Mexican children.

Mejía-Benítez A, Klünder-Klünder M, Yengo L, Meyre D, Aradillas C, Cruz E, Pérez-Luque E, Malacara JM, Garay ME, Peralta-Romero J, Flores-Huerta S, García-Mena J, Froguel P, Cruz M, Bonnefond A.

BMC Med Genet. 2013 Feb 1;14:21. doi: 10.1186/1471-2350-14-21.


The contribution of FTO and UCP-1 SNPs to extreme obesity, diabetes and cardiovascular risk in Brazilian individuals.

Ramos AV, Bastos-Rodrigues L, Resende BA, Friedman E, Campanha-Versiani L, Miranda DM, Sarquis M, De Marco L.

BMC Med Genet. 2012 Nov 7;13:101. doi: 10.1186/1471-2350-13-101.


Contribution of 24 obesity-associated genetic variants to insulin resistance, pancreatic beta-cell function and type 2 diabetes risk in the French population.

Robiou-du-Pont S, Bonnefond A, Yengo L, Vaillant E, Lobbens S, Durand E, Weill J, Lantieri O, Balkau B, Charpentier G, Marre M, Froguel P, Meyre D.

Int J Obes (Lond). 2013 Jul;37(7):980-5. doi: 10.1038/ijo.2012.175. Epub 2012 Oct 23.


Implication of European-derived adiposity loci in African Americans.

Hester JM, Wing MR, Li J, Palmer ND, Xu J, Hicks PJ, Roh BH, Norris JM, Wagenknecht LE, Langefeld CD, Freedman BI, Bowden DW, Ng MC.

Int J Obes (Lond). 2012 Mar;36(3):465-73. doi: 10.1038/ijo.2011.131. Epub 2011 Jul 12.


Genes and lifestyle factors in obesity: results from 12,462 subjects from MONICA/KORA.

Holzapfel C, Grallert H, Huth C, Wahl S, Fischer B, Döring A, Rückert IM, Hinney A, Hebebrand J, Wichmann HE, Hauner H, Illig T, Heid IM.

Int J Obes (Lond). 2010 Oct;34(10):1538-45. doi: 10.1038/ijo.2010.79. Epub 2010 Apr 13.


Obesity susceptibility genetic variants identified from recent genome-wide association studies: implications in a chinese population.

Cheung CY, Tso AW, Cheung BM, Xu A, Ong KL, Fong CH, Wat NM, Janus ED, Sham PC, Lam KS.

J Clin Endocrinol Metab. 2010 Mar;95(3):1395-403. doi: 10.1210/jc.2009-1465. Epub 2010 Jan 8.


Physical activity attenuates the genetic predisposition to obesity in 20,000 men and women from EPIC-Norfolk prospective population study.

Li S, Zhao JH, Luan J, Ekelund U, Luben RN, Khaw KT, Wareham NJ, Loos RJ.

PLoS Med. 2010 Aug 31;7(8). pii: e1000332. doi: 10.1371/journal.pmed.1000332.


Frequencies of obesity susceptibility alleles among ethnically and racially diverse bariatric patient populations.

Parikh M, Hetherington J, Sheth S, Seiler J, Ostrer H, Gerhard G, Wood C, Still C.

Surg Obes Relat Dis. 2013 May-Jun;9(3):436-41. doi: 10.1016/j.soard.2012.04.004. Epub 2012 May 8.


Genome-wide association scan shows genetic variants in the FTO gene are associated with obesity-related traits.

Scuteri A, Sanna S, Chen WM, Uda M, Albai G, Strait J, Najjar S, Nagaraja R, Orrú M, Usala G, Dei M, Lai S, Maschio A, Busonero F, Mulas A, Ehret GB, Fink AA, Weder AB, Cooper RS, Galan P, Chakravarti A, Schlessinger D, Cao A, Lakatta E, Abecasis GR.

PLoS Genet. 2007 Jul;3(7):e115.


Study of eight GWAS-identified common variants for association with obesity-related indices in Chinese children at puberty.

Wang J, Mei H, Chen W, Jiang Y, Sun W, Li F, Fu Q, Jiang F.

Int J Obes (Lond). 2012 Apr;36(4):542-7. doi: 10.1038/ijo.2011.218. Epub 2011 Nov 15.


Common variation in the fat mass and obesity-associated (FTO) gene confers risk of obesity and modulates BMI in the Chinese population.

Chang YC, Liu PH, Lee WJ, Chang TJ, Jiang YD, Li HY, Kuo SS, Lee KC, Chuang LM.

Diabetes. 2008 Aug;57(8):2245-52. doi: 10.2337/db08-0377. Epub 2008 May 16.


Polymorphisms in the NPY2R gene show significant associations with BMI that are additive to FTO, MC4R, and NPFFR2 gene effects.

Hunt SC, Hasstedt SJ, Xin Y, Dalley BK, Milash BA, Yakobson E, Gress RE, Davidson LE, Adams TD.

Obesity (Silver Spring). 2011 Nov;19(11):2241-7. doi: 10.1038/oby.2011.239. Epub 2011 Aug 4.


Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples.

den Hoed M, Luan J, Langenberg C, Cooper C, Sayer AA, Jameson K, Kumari M, Kivimaki M, Hingorani AD, Grøntved A, Khaw KT, Ekelund U, Wareham NJ, Loos RJ.

Int J Obes (Lond). 2013 Feb;37(2):191-6. doi: 10.1038/ijo.2012.34. Epub 2012 Mar 20.


Cumulative effects and predictive value of common obesity-susceptibility variants identified by genome-wide association studies.

Li S, Zhao JH, Luan J, Luben RN, Rodwell SA, Khaw KT, Ong KK, Wareham NJ, Loos RJ.

Am J Clin Nutr. 2010 Jan;91(1):184-90. doi: 10.3945/ajcn.2009.28403. Epub 2009 Oct 7.


A systematic mapping approach of 16q12.2/FTO and BMI in more than 20,000 African Americans narrows in on the underlying functional variation: results from the Population Architecture using Genomics and Epidemiology (PAGE) study.

Peters U, North KE, Sethupathy P, Buyske S, Haessler J, Jiao S, Fesinmeyer MD, Jackson RD, Kuller LH, Rajkovic A, Lim U, Cheng I, Schumacher F, Wilkens L, Li R, Monda K, Ehret G, Nguyen KD, Cooper R, Lewis CE, Leppert M, Irvin MR, Gu CC, Houston D, Buzkova P, Ritchie M, Matise TC, Le Marchand L, Hindorff LA, Crawford DC, Haiman CA, Kooperberg C.

PLoS Genet. 2013;9(1):e1003171. doi: 10.1371/journal.pgen.1003171. Epub 2013 Jan 17.


FTO polymorphisms are associated with obesity but not diabetes risk in postmenopausal women.

Song Y, You NC, Hsu YH, Howard BV, Langer RD, Manson JE, Nathan L, Niu T, F Tinker L, Liu S.

Obesity (Silver Spring). 2008 Nov;16(11):2472-80. doi: 10.1038/oby.2008.408. Epub 2008 Sep 11.


Sex-dependent associations of genetic variants identified by GWAS with indices of adiposity and obesity risk in a Chinese children population.

Xi B, Shen Y, Reilly KH, Zhao X, Cheng H, Hou D, Wang X, Mi J.

Clin Endocrinol (Oxf). 2013 Oct;79(4):523-8. doi: 10.1111/cen.12091. Epub 2013 Apr 13.


Genetic susceptibility, birth weight and obesity risk in young Chinese.

Hong J, Shi J, Qi L, Cui B, Gu W, Zhang Y, Li L, Xu M, Wang L, Zhai Y, Miao L, Wang R, Bi Y, Wang W, Ning G.

Int J Obes (Lond). 2013 May;37(5):673-7. doi: 10.1038/ijo.2012.87. Epub 2012 Jun 19.


Effects of established BMI-associated loci on obesity-related traits in a French representative population sample.

Goumidi L, Cottel D, Dallongeville J, Amouyel P, Meirhaeghe A.

BMC Genet. 2014 May 23;15:62. doi: 10.1186/1471-2156-15-62.

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