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Items: 1 to 20 of 96

1.

Working in concert: the metalloaminopeptidases from Plasmodium falciparum.

McGowan S.

Curr Opin Struct Biol. 2013 Dec;23(6):828-35. doi: 10.1016/j.sbi.2013.07.015. Epub 2013 Aug 13. Review.

2.

Aminopeptidases of malaria parasites: new targets for chemotherapy.

Trenholme KR, Brown CL, Skinner-Adams TS, Stack C, Lowther J, To J, Robinson MW, Donnelly SM, Dalton JP, Gardiner DL.

Infect Disord Drug Targets. 2010 Jun;10(3):217-25. Review.

PMID:
20334618
3.

Protease-associated cellular networks in malaria parasite Plasmodium falciparum.

Lilburn TG, Cai H, Zhou Z, Wang Y.

BMC Genomics. 2011 Dec 23;12 Suppl 5:S9. doi: 10.1186/1471-2164-12-S5-S9. Epub 2011 Dec 23.

4.

Plasmodium falciparum: new molecular targets with potential for antimalarial drug development.

Gardiner DL, Skinner-Adams TS, Brown CL, Andrews KT, Stack CM, McCarthy JS, Dalton JP, Trenholme KR.

Expert Rev Anti Infect Ther. 2009 Nov;7(9):1087-98. doi: 10.1586/eri.09.93. Review.

PMID:
19883329
5.

Threonine peptidases as drug targets against malaria.

Tschan S, Mordmüller B, Kun JF.

Expert Opin Ther Targets. 2011 Apr;15(4):365-78. doi: 10.1517/14728222.2011.555399. Epub 2011 Feb 1. Review.

PMID:
21281254
6.

Plasmodium kinases as targets for new-generation antimalarials.

Lucet IS, Tobin A, Drewry D, Wilks AF, Doerig C.

Future Med Chem. 2012 Dec;4(18):2295-310. doi: 10.4155/fmc.12.183. Review.

PMID:
23234552
7.

Plasmodium falciparum neutral aminopeptidases: new targets for anti-malarials.

Skinner-Adams TS, Stack CM, Trenholme KR, Brown CL, Grembecka J, Lowther J, Mucha A, Drag M, Kafarski P, McGowan S, Whisstock JC, Gardiner DL, Dalton JP.

Trends Biochem Sci. 2010 Jan;35(1):53-61. doi: 10.1016/j.tibs.2009.08.004. Epub 2009 Sep 30. Review.

PMID:
19796954
8.

Disruption of a mitochondrial protease machinery in Plasmodium falciparum is an intrinsic signal for parasite cell death.

Rathore S, Jain S, Sinha D, Gupta M, Asad M, Srivastava A, Narayanan MS, Ramasamy G, Chauhan VS, Gupta D, Mohmmed A.

Cell Death Dis. 2011 Nov 24;2:e231. doi: 10.1038/cddis.2011.118.

9.

Helicases - feasible antimalarial drug target for Plasmodium falciparum.

Tuteja R.

FEBS J. 2007 Sep;274(18):4699-704. Review.

10.

Chemical target validation studies of aminopeptidase in malaria parasites using alpha-aminoalkylphosphonate and phosphonopeptide inhibitors.

Cunningham E, Drag M, Kafarski P, Bell A.

Antimicrob Agents Chemother. 2008 Sep;52(9):3221-8. doi: 10.1128/AAC.01327-07. Epub 2008 May 5.

11.

Specific inhibition of the aspartate aminotransferase of Plasmodium falciparum.

Wrenger C, Müller IB, Schifferdecker AJ, Jain R, Jordanova R, Groves MR.

J Mol Biol. 2011 Jan 28;405(4):956-71. doi: 10.1016/j.jmb.2010.11.018. Epub 2010 Nov 16.

PMID:
21087616
12.

Targeting Plasmodium falciparum purine salvage enzymes: a look at structure-based drug development.

Donaldson T, Kim K.

Infect Disord Drug Targets. 2010 Jun;10(3):191-9. Review.

PMID:
20480551
13.

Selective inhibition of an apicoplastic aminoacyl-tRNA synthetase from Plasmodium falciparum.

Hoen R, Novoa EM, López A, Camacho N, Cubells L, Vieira P, Santos M, Marin-Garcia P, Bautista JM, Cortés A, Ribas de Pouplana L, Royo M.

Chembiochem. 2013 Mar 4;14(4):499-509. doi: 10.1002/cbic.201200620.

PMID:
23444099
14.

Network-based assessment of the selectivity of metabolic drug targets in Plasmodium falciparum with respect to human liver metabolism.

Bazzani S, Hoppe A, Holzhütter HG.

BMC Syst Biol. 2012 Aug 31;6:118. doi: 10.1186/1752-0509-6-118.

15.

Predicting functional residues in Plasmodium falciparum plasmepsins by combining sequence and structural analysis with molecular dynamics simulations.

Valiente PA, Batista PR, Pupo A, Pons T, Valencia A, Pascutti PG.

Proteins. 2008 Nov 1;73(2):440-57. doi: 10.1002/prot.22068.

PMID:
18442137
16.

Structure and Substrate Fingerprint of Aminopeptidase P from  Plasmodium falciparum.

Drinkwater N, Kannan Sivaraman K, Bamert RS, Rut W, Mohamed K, Vinh NB, Scammells PJ, Drag M, McGowan S.

Biochem J. 2016 Jul 26. pii: BCJ20160550. [Epub ahead of print]

PMID:
27462122
17.
18.

Proteases of Plasmodium falciparum as potential drug targets and inhibitors thereof.

Wegscheid-Gerlach C, Gerber HD, Diederich WE.

Curr Top Med Chem. 2010;10(3):346-67. Review.

PMID:
20166950
19.

Falcipains, Plasmodium falciparum cysteine proteases as key drug targets against malaria.

Teixeira C, Gomes JR, Gomes P.

Curr Med Chem. 2011;18(10):1555-72. Review.

PMID:
21428877
20.

The Plasmodium falciparum malaria M1 alanyl aminopeptidase (PfA-M1): insights of catalytic mechanism and function from MD simulations.

Jones PM, Robinson MW, Dalton JP, George AM.

PLoS One. 2011;6(12):e28589. doi: 10.1371/journal.pone.0028589. Epub 2011 Dec 21.

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