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Results: 1 to 20 of 124

Related Citations for PubMed (Select 23947814)

1.

Structural characterization of more potent alternatives to HAMLET, a tumoricidal complex of α-lactalbumin and oleic acid.

Nemashkalova EL, Kazakov AS, Khasanova LM, Permyakov EA, Permyakov SE.

Biochemistry. 2013 Sep 10;52(36):6286-99. doi: 10.1021/bi400643s. Epub 2013 Aug 27.

PMID:
23947814
2.

Oleic acid is a key cytotoxic component of HAMLET-like complexes.

Permyakov SE, Knyazeva EL, Khasanova LM, Fadeev RS, Zhadan AP, Roche-Hakansson H, Håkansson AP, Akatov VS, Permyakov EA.

Biol Chem. 2012 Jan;393(1-2):85-92. doi: 10.1515/BC-2011-230.

PMID:
22628302
3.

Bovine lactoferrin binds oleic acid to form an anti-tumor complex similar to HAMLET.

Fang B, Zhang M, Tian M, Jiang L, Guo HY, Ren FZ.

Biochim Biophys Acta. 2014 Apr 4;1841(4):535-43. doi: 10.1016/j.bbalip.2013.12.008. Epub 2013 Dec 22.

4.

Cytotoxicity of bovine α-lactalbumin: oleic acid complexes correlates with the disruption of lipid membranes.

Wen H, Glomm WR, Halskau O.

Biochim Biophys Acta. 2013 Nov;1828(11):2691-9. doi: 10.1016/j.bbamem.2013.07.026. Epub 2013 Jul 31.

5.

Electrostatic interactions play an essential role in the binding of oleic acid with α-lactalbumin in the HAMLET-like complex: a study using charge-specific chemical modifications.

Xie Y, Min S, Harte NP, Kirk H, O'Brien JE, Voorheis HP, Svanborg C, Hun Mok K.

Proteins. 2013 Jan;81(1):1-17. doi: 10.1002/prot.24141. Epub 2012 Sep 29.

PMID:
22777854
6.

Structure and function of human α-lactalbumin made lethal to tumor cells (HAMLET)-type complexes.

Mossberg AK, Hun Mok K, Morozova-Roche LA, Svanborg C.

FEBS J. 2010 Nov;277(22):4614-25. doi: 10.1111/j.1742-4658.2010.07890.x. Review.

PMID:
20977665
7.

The oleic acid complexes of proteolytic fragments of alpha-lactalbumin display apoptotic activity.

Tolin S, De Franceschi G, Spolaore B, Frare E, Canton M, Polverino de Laureto P, Fontana A.

FEBS J. 2010 Jan;277(1):163-73. doi: 10.1111/j.1742-4658.2009.07466.x. Epub 2009 Nov 26.

PMID:
19968717
8.

Who is Mr. HAMLET? Interaction of human alpha-lactalbumin with monomeric oleic acid.

Knyazeva EL, Grishchenko VM, Fadeev RS, Akatov VS, Permyakov SE, Permyakov EA.

Biochemistry. 2008 Dec 9;47(49):13127-37. doi: 10.1021/bi801423s.

PMID:
19006329
9.

A novel method for preparation of HAMLET-like protein complexes.

Permyakov SE, Knyazeva EL, Leonteva MV, Fadeev RS, Chekanov AV, Zhadan AP, Håkansson AP, Akatov VS, Permyakov EA.

Biochimie. 2011 Sep;93(9):1495-501. doi: 10.1016/j.biochi.2011.05.002. Epub 2011 May 11.

PMID:
21596091
10.

Applications of site-specific labeling to study HAMLET, a tumoricidal complex of α-lactalbumin and oleic acid.

Mercer N, Ramakrishnan B, Boeggeman E, Qasba PK.

PLoS One. 2011;6(10):e26093. doi: 10.1371/journal.pone.0026093. Epub 2011 Oct 10.

11.

HAMLET forms annular oligomers when deposited with phospholipid monolayers.

Baumann A, Gjerde AU, Ying M, Svanborg C, Holmsen H, Glomm WR, Martinez A, Halskau O.

J Mol Biol. 2012 Apr 20;418(1-2):90-102. doi: 10.1016/j.jmb.2012.02.006. Epub 2012 Feb 16.

12.

Interaction of antitumor alpha-lactalbumin-oleic acid complexes with artificial and natural membranes.

Zherelova OM, Kataev AA, Grishchenko VM, Knyazeva EL, Permyakov SE, Permyakov EA.

J Bioenerg Biomembr. 2009 Jun;41(3):229-37. doi: 10.1007/s10863-009-9222-x. Epub 2009 Jul 9.

PMID:
19588235
13.

alpha-Lactalbumin, engineered to be nonnative and inactive, kills tumor cells when in complex with oleic acid: a new biological function resulting from partial unfolding.

Pettersson-Kastberg J, Mossberg AK, Trulsson M, Yong YJ, Min S, Lim Y, O'Brien JE, Svanborg C, Mok KH.

J Mol Biol. 2009 Dec 18;394(5):994-1010. doi: 10.1016/j.jmb.2009.09.026. Epub 2009 Sep 18.

PMID:
19766653
14.

Low resolution solution structure of HAMLET and the importance of its alpha-domains in tumoricidal activity.

Ho CS, Rydstrom A, Manimekalai MS, Svanborg C, Grüber G.

PLoS One. 2012;7(12):e53051. doi: 10.1371/journal.pone.0053051. Epub 2012 Dec 27.

15.

Stability of HAMLET--a kinetically trapped alpha-lactalbumin oleic acid complex.

Fast J, Mossberg AK, Svanborg C, Linse S.

Protein Sci. 2005 Feb;14(2):329-40.

16.

α-Lactalbumin forms with oleic acid a high molecular weight complex displaying cytotoxic activity.

Spolaore B, Pinato O, Canton M, Zambonin M, Polverino de Laureto P, Fontana A.

Biochemistry. 2010 Oct 5;49(39):8658-67. doi: 10.1021/bi1012832. Epub 2010 Sep 9.

PMID:
20804154
17.

alpha-Lactalbumin species variation, HAMLET formation, and tumor cell death.

Pettersson J, Mossberg AK, Svanborg C.

Biochem Biophys Res Commun. 2006 Jun 23;345(1):260-70. Epub 2006 Apr 27.

PMID:
16678133
18.

Lipids as tumoricidal components of human α-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death.

Ho JC, Storm P, Rydström A, Bowen B, Alsin F, Sullivan L, Ambite I, Mok KH, Northen T, Svanborg C.

J Biol Chem. 2013 Jun 14;288(24):17460-71. doi: 10.1074/jbc.M113.468405. Epub 2013 Apr 29.

19.

Alpha-lactalbumin unfolding is not sufficient to cause apoptosis, but is required for the conversion to HAMLET (human alpha-lactalbumin made lethal to tumor cells).

Svensson M, Fast J, Mossberg AK, Düringer C, Gustafsson L, Hallgren O, Brooks CL, Berliner L, Linse S, Svanborg C.

Protein Sci. 2003 Dec;12(12):2794-804.

20.

pH and ionic strength dependence of protein (un)folding and ligand binding to bovine beta-lactoglobulins A and B.

Beringhelli T, Eberini I, Galliano M, Pedoto A, Perduca M, Sportiello A, Fontana E, Monaco HL, Gianazza E.

Biochemistry. 2002 Dec 24;41(51):15415-22.

PMID:
12484782
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