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Results: 1 to 20 of 112

Similar articles for PubMed (Select 23945932)

1.

In silico abstraction of zinc finger nuclease cleavage profiles reveals an expanded landscape of off-target sites.

Sander JD, Ramirez CL, Linder SJ, Pattanayak V, Shoresh N, Ku M, Foden JA, Reyon D, Bernstein BE, Liu DR, Joung JK.

Nucleic Acids Res. 2013 Oct;41(19):e181. doi: 10.1093/nar/gkt716. Epub 2013 Aug 14.

2.

An online bioinformatics tool predicts zinc finger and TALE nuclease off-target cleavage.

Fine EJ, Cradick TJ, Zhao CL, Lin Y, Bao G.

Nucleic Acids Res. 2014 Apr;42(6):e42. doi: 10.1093/nar/gkt1326. Epub 2013 Dec 30.

3.

ZFN-site searches genomes for zinc finger nuclease target sites and off-target sites.

Cradick TJ, Ambrosini G, Iseli C, Bucher P, McCaffrey AP.

BMC Bioinformatics. 2011 May 13;12:152. doi: 10.1186/1471-2105-12-152.

4.

Creating designed zinc-finger nucleases with minimal cytotoxicity.

Ramalingam S, Kandavelou K, Rajenderan R, Chandrasegaran S.

J Mol Biol. 2011 Jan 21;405(3):630-41. doi: 10.1016/j.jmb.2010.10.043. Epub 2010 Nov 19.

5.

Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection.

Pattanayak V, Ramirez CL, Joung JK, Liu DR.

Nat Methods. 2011 Aug 7;8(9):765-70. doi: 10.1038/nmeth.1670.

6.

Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly.

Kim HJ, Lee HJ, Kim H, Cho SW, Kim JS.

Genome Res. 2009 Jul;19(7):1279-88. doi: 10.1101/gr.089417.108. Epub 2009 May 21.

7.

Enhanced cleavage of double-stranded DNA by artificial zinc-finger nuclease sandwiched between two zinc-finger proteins.

Mineta Y, Okamoto T, Takenaka K, Doi N, Aoyama Y, Sera T.

Biochemistry. 2008 Nov 25;47(47):12257-9. doi: 10.1021/bi801800k.

PMID:
18980382
8.

Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction.

Olsen PA, Gelazauskaite M, Randøl M, Krauss S.

BMC Mol Biol. 2010 May 10;11:35. doi: 10.1186/1471-2199-11-35.

9.

ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms.

Reyon D, Kirkpatrick JR, Sander JD, Zhang F, Voytas DF, Joung JK, Dobbs D, Coffman CR.

BMC Genomics. 2011 Jan 28;12:83. doi: 10.1186/1471-2164-12-83.

10.

Quantification of zinc finger nuclease-associated toxicity.

Cornu TI, Cathomen T.

Methods Mol Biol. 2010;649:237-45. doi: 10.1007/978-1-60761-753-2_14.

PMID:
20680838
11.

Identification of off-target cleavage sites of zinc finger nucleases and TAL effector nucleases using predictive models.

Fine EJ, Cradick TJ, Bao G.

Methods Mol Biol. 2014;1114:371-83. doi: 10.1007/978-1-62703-761-7_24.

PMID:
24557916
12.

Knockout of exogenous EGFP gene in porcine somatic cells using zinc-finger nucleases.

Watanabe M, Umeyama K, Matsunari H, Takayanagi S, Haruyama E, Nakano K, Fujiwara T, Ikezawa Y, Nakauchi H, Nagashima H.

Biochem Biophys Res Commun. 2010 Nov 5;402(1):14-8. doi: 10.1016/j.bbrc.2010.09.092. Epub 2010 Sep 26.

PMID:
20875794
13.

Zinc finger protein-dependent and -independent contributions to the in vivo off-target activity of zinc finger nucleases.

Gupta A, Meng X, Zhu LJ, Lawson ND, Wolfe SA.

Nucleic Acids Res. 2011 Jan;39(1):381-92. doi: 10.1093/nar/gkq787. Epub 2010 Sep 14.

14.

An unbiased genome-wide analysis of zinc-finger nuclease specificity.

Gabriel R, Lombardo A, Arens A, Miller JC, Genovese P, Kaeppel C, Nowrouzi A, Bartholomae CC, Wang J, Friedman G, Holmes MC, Gregory PD, Glimm H, Schmidt M, Naldini L, von Kalle C.

Nat Biotechnol. 2011 Aug 7;29(9):816-23. doi: 10.1038/nbt.1948.

PMID:
21822255
15.

TALENs facilitate targeted genome editing in human cells with high specificity and low cytotoxicity.

Mussolino C, Alzubi J, Fine EJ, Morbitzer R, Cradick TJ, Lahaye T, Bao G, Cathomen T.

Nucleic Acids Res. 2014 Jun;42(10):6762-73. doi: 10.1093/nar/gku305. Epub 2014 May 3.

16.

An improved zinc-finger nuclease architecture for highly specific genome editing.

Miller JC, Holmes MC, Wang J, Guschin DY, Lee YL, Rupniewski I, Beausejour CM, Waite AJ, Wang NS, Kim KA, Gregory PD, Pabo CO, Rebar EJ.

Nat Biotechnol. 2007 Jul;25(7):778-85. Epub 2007 Jul 1.

PMID:
17603475
17.

Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme.

Wang J, Friedman G, Doyon Y, Wang NS, Li CJ, Miller JC, Hua KL, Yan JJ, Babiarz JE, Gregory PD, Holmes MC.

Genome Res. 2012 Jul;22(7):1316-26. doi: 10.1101/gr.122879.111. Epub 2012 Mar 20.

18.

Creating zinc finger nucleases to manipulate the genome in a site-specific manner using a modular-assembly approach.

Porteus M.

Cold Spring Harb Protoc. 2010 Dec 1;2010(12):pdb.top93. doi: 10.1101/pdb.top93.

PMID:
21123434
19.

Engineered zinc finger nickases induce homology-directed repair with reduced mutagenic effects.

Ramirez CL, Certo MT, Mussolino C, Goodwin MJ, Cradick TJ, McCaffrey AP, Cathomen T, Scharenberg AM, Joung JK.

Nucleic Acids Res. 2012 Jul;40(12):5560-8. doi: 10.1093/nar/gks179. Epub 2012 Feb 28.

20.

Autonomous zinc-finger nuclease pairs for targeted chromosomal deletion.

Söllü C, Pars K, Cornu TI, Thibodeau-Beganny S, Maeder ML, Joung JK, Heilbronn R, Cathomen T.

Nucleic Acids Res. 2010 Dec;38(22):8269-76. doi: 10.1093/nar/gkq720. Epub 2010 Aug 16.

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