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Items: 1 to 20 of 158


TNF-α and CD8+ T cells mediate the beneficial effects of nitric oxide synthase-2 deficiency in pulmonary paracoccidioidomycosis.

Bernardino S, Pina A, Felonato M, Costa TA, Frank de Araújo E, Feriotti C, Bazan SB, Keller AC, Leite KR, Calich VL.

PLoS Negl Trop Dis. 2013 Aug 1;7(8):e2325. doi: 10.1371/journal.pntd.0002325. Print 2013.


In pulmonary paracoccidioidomycosis IL-10 deficiency leads to increased immunity and regressive infection without enhancing tissue pathology.

Costa TA, Bazan SB, Feriotti C, Araújo EF, Bassi Ê, Loures FV, Calich VL.

PLoS Negl Trop Dis. 2013 Oct 24;7(10):e2512. doi: 10.1371/journal.pntd.0002512. eCollection 2013.


Toll-like receptor 4 signaling leads to severe fungal infection associated with enhanced proinflammatory immunity and impaired expansion of regulatory T cells.

Loures FV, Pina A, Felonato M, Araújo EF, Leite KR, Calich VL.

Infect Immun. 2010 Mar;78(3):1078-88. doi: 10.1128/IAI.01198-09. Epub 2009 Dec 14.


Anti-CD25 treatment depletes Treg cells and decreases disease severity in susceptible and resistant mice infected with Paracoccidioides brasiliensis.

Felonato M, Pina A, de Araujo EF, Loures FV, Bazan SB, Feriotti C, Calich VL.

PLoS One. 2012;7(11):e51071. doi: 10.1371/journal.pone.0051071. Epub 2012 Nov 30.


Absence of interleukin-4 determines less severe pulmonary paracoccidioidomycosis associated with impaired Th2 response.

Pina A, Valente-Ferreira RC, Molinari-Madlum EE, Vaz CA, Keller AC, Calich VL.

Infect Immun. 2004 Apr;72(4):2369-78.


CD28 exerts protective and detrimental effects in a pulmonary model of paracoccidioidomycosis.

Felonato M, Pina A, Bernardino S, Loures FV, de Araujo EF, Calich VL.

Infect Immun. 2010 Nov;78(11):4922-35. doi: 10.1128/IAI.00297-10. Epub 2010 Aug 16.


Inducible nitric oxide synthase-deficient mice show exacerbated inflammatory process and high production of both Th1 and Th2 cytokines during paracoccidioidomycosis.

Livonesi MC, Rossi MA, de Souto JT, Campanelli AP, de Sousa RL, Maffei CM, Ferreira BR, Martinez R, da Silva JS.

Microbes Infect. 2009 Jan;11(1):123-32. doi: 10.1016/j.micinf.2008.10.015. Epub 2008 Nov 24.


Depletion of CD8(+) T cells in vivo impairs host defense of mice resistant and susceptible to pulmonary paracoccidioidomycosis.

Cano LE, Singer-Vermes LM, Costa TA, Mengel JO, Xidieh CF, Arruda C, André DC, Vaz CA, Burger E, Calich VL.

Infect Immun. 2000 Jan;68(1):352-9.


The relative importance of CD4+ and CD8+T cells in immunity to pulmonary paracoccidioidomycosis.

Chiarella AP, Arruda C, Pina A, Costa TA, Ferreira RC, Calich VL.

Microbes Infect. 2007 Jul;9(9):1078-88. Epub 2007 May 17.


Dectin-1 induces M1 macrophages and prominent expansion of CD8+IL-17+ cells in pulmonary Paracoccidioidomycosis.

Loures FV, Araújo EF, Feriotti C, Bazan SB, Costa TA, Brown GD, Calich VL.

J Infect Dis. 2014 Sep 1;210(5):762-73. doi: 10.1093/infdis/jiu136. Epub 2014 Mar 5.


Neutrophil role in pulmonary paracoccidioidomycosis depends on the resistance pattern of hosts.

Pina A, Saldiva PH, Restrepo LE, Calich VL.

J Leukoc Biol. 2006 Jun;79(6):1202-13. Epub 2006 Apr 7.


Nitric oxide participation in granulomatous response induced by Paracoccidioides brasiliensis infection in mice.

Nishikaku AS, Molina RF, Ribeiro LC, Scavone R, Albe BP, Cunha CS, Burger E.

Med Microbiol Immunol. 2009 May;198(2):123-35. doi: 10.1007/s00430-009-0113-x. Epub 2009 Apr 10.


CCR5-dependent regulatory T cell migration mediates fungal survival and severe immunosuppression.

Moreira AP, Cavassani KA, Massafera Tristão FS, Campanelli AP, Martinez R, Rossi MA, Silva JS.

J Immunol. 2008 Mar 1;180(5):3049-56.


B cell-deficient mice display enhanced susceptibility to Paracoccidioides brasiliensis Infection.

Tristão FS, Panagio LA, Rocha FA, Cavassani KA, Moreira AP, Rossi MA, Silva JS.

Mycopathologia. 2013 Aug;176(1-2):1-10. doi: 10.1007/s11046-013-9671-y. Epub 2013 Jun 14.


Interferon-gamma and tumor necrosis factor-alpha determine resistance to Paracoccidioides brasiliensis infection in mice.

Souto JT, Figueiredo F, Furlanetto A, Pfeffer K, Rossi MA, Silva JS.

Am J Pathol. 2000 May;156(5):1811-20.


Role of interleukin (IL)-18 in experimental paracoccidioidomycosis.

Panagio LA, Tristao FS, Moreira AP, Pereira MS, Cavassani KA, Milanezi CM, Rossi MA, Silva JS.

Med Mycol. 2008 Aug;46(5):435-42. doi: 10.1080/13693780801895444. Epub 2008 Mar 5.


Treatment of Paracoccidioides brasiliensis-infected mice with a nitric oxide inhibitor prevents the failure of cell-mediated immune response.

Bocca AL, Hayashi EE, Pinheiro AG, Furlanetto AB, Campanelli AP, Cunha FQ, Figueiredo F.

J Immunol. 1998 Sep 15;161(6):3056-63.


Mannosyl-recognizing receptors induce an M1-like phenotype in macrophages of susceptible mice but an M2-like phenotype in mice resistant to a fungal infection.

Feriotti C, Loures FV, Frank de Araújo E, da Costa TA, Calich VL.

PLoS One. 2013;8(1):e54845. doi: 10.1371/journal.pone.0054845. Epub 2013 Jan 30.

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