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Related Citations for PubMed (Select 23934151)


The Mll2 branch of the COMPASS family regulates bivalent promoters in mouse embryonic stem cells.

Hu D, Garruss AS, Gao X, Morgan MA, Cook M, Smith ER, Shilatifard A.

Nat Struct Mol Biol. 2013 Sep;20(9):1093-7. doi: 10.1038/nsmb.2653. Epub 2013 Aug 11.


Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.

Denissov S, Hofemeister H, Marks H, Kranz A, Ciotta G, Singh S, Anastassiadis K, Stunnenberg HG, Stewart AF.

Development. 2014 Feb;141(3):526-37. doi: 10.1242/dev.102681. Epub 2014 Jan 14.


Chromatin changes in dicer-deficient mouse embryonic stem cells in response to retinoic acid induced differentiation.

Tennakoon JB, Wang H, Coarfa C, Cooney AJ, Gunaratne PH.

PLoS One. 2013 Sep 9;8(9):e74556. doi: 10.1371/journal.pone.0074556. eCollection 2013.


A double take on bivalent promoters.

Voigt P, Tee WW, Reinberg D.

Genes Dev. 2013 Jun 15;27(12):1318-38. doi: 10.1101/gad.219626.113. Review.


The histone methyltransferase KMT2B is required for RNA polymerase II association and protection from DNA methylation at the MagohB CpG island promoter.

Ladopoulos V, Hofemeister H, Hoogenkamp M, Riggs AD, Stewart AF, Bonifer C.

Mol Cell Biol. 2013 Apr;33(7):1383-93. doi: 10.1128/MCB.01721-12. Epub 2013 Jan 28.


Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.

Lee MG, Villa R, Trojer P, Norman J, Yan KP, Reinberg D, Di Croce L, Shiekhattar R.

Science. 2007 Oct 19;318(5849):447-50. Epub 2007 Aug 30.


Histone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos.

Dahl JA, Reiner AH, Klungland A, Wakayama T, Collas P.

PLoS One. 2010 Feb 10;5(2):e9150. doi: 10.1371/journal.pone.0009150.


Whole-genome analysis of histone H3 lysine 4 and lysine 27 methylation in human embryonic stem cells.

Pan G, Tian S, Nie J, Yang C, Ruotti V, Wei H, Jonsdottir GA, Stewart R, Thomson JA.

Cell Stem Cell. 2007 Sep 13;1(3):299-312. doi: 10.1016/j.stem.2007.08.003.


Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains.

Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG.

Cell. 2011 Feb 18;144(4):513-25. doi: 10.1016/j.cell.2011.01.020. Erratum in: Cell. 2011 Mar 4;144(5):825.


Ubiquitin E3 ligase Ring1b/Rnf2 of polycomb repressive complex 1 contributes to stable maintenance of mouse embryonic stem cells.

van der Stoop P, Boutsma EA, Hulsman D, Noback S, Heimerikx M, Kerkhoven RM, Voncken JW, Wessels LF, van Lohuizen M.

PLoS One. 2008 May 21;3(5):e2235. doi: 10.1371/journal.pone.0002235.


Myc regulates the transcription of the PRC2 gene to control the expression of developmental genes in embryonic stem cells.

Neri F, Zippo A, Krepelova A, Cherubini A, Rocchigiani M, Oliviero S.

Mol Cell Biol. 2012 Feb;32(4):840-51. doi: 10.1128/MCB.06148-11. Epub 2011 Dec 19.


KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation.

Kidder BL, Hu G, Zhao K.

Genome Biol. 2014 Feb 4;15(2):R32. doi: 10.1186/gb-2014-15-2-r32.


An epigenetic signature of developmental potential in neural stem cells and early neurons.

Burney MJ, Johnston C, Wong KY, Teng SW, Beglopoulos V, Stanton LW, Williams BP, Bithell A, Buckley NJ.

Stem Cells. 2013 Sep;31(9):1868-80. doi: 10.1002/stem.1431.


LSD1 regulates the balance between self-renewal and differentiation in human embryonic stem cells.

Adamo A, Sesé B, Boue S, Castaño J, Paramonov I, Barrero MJ, Izpisua Belmonte JC.

Nat Cell Biol. 2011 Jun;13(6):652-9. doi: 10.1038/ncb2246. Epub 2011 May 22.


Epigenetic signatures and temporal expression of lineage-specific genes in hESCs during differentiation to hepatocytes in vitro.

Kim H, Jang MJ, Kang MJ, Han YM.

Hum Mol Genet. 2011 Feb 1;20(3):401-12. doi: 10.1093/hmg/ddq476. Epub 2010 Nov 8.


Dnmt3L antagonizes DNA methylation at bivalent promoters and favors DNA methylation at gene bodies in ESCs.

Neri F, Krepelova A, Incarnato D, Maldotti M, Parlato C, Galvagni F, Matarese F, Stunnenberg HG, Oliviero S.

Cell. 2013 Sep 26;155(1):121-34. doi: 10.1016/j.cell.2013.08.056.


MLL2 is required in oocytes for bulk histone 3 lysine 4 trimethylation and transcriptional silencing.

Andreu-Vieyra CV, Chen R, Agno JE, Glaser S, Anastassiadis K, Stewart AF, Matzuk MM.

PLoS Biol. 2010 Aug 17;8(8). pii: e1000453. doi: 10.1371/journal.pbio.1000453.


H3K9 and H3K14 acetylation co-occur at many gene regulatory elements, while H3K14ac marks a subset of inactive inducible promoters in mouse embryonic stem cells.

Karmodiya K, Krebs AR, Oulad-Abdelghani M, Kimura H, Tora L.

BMC Genomics. 2012 Aug 24;13:424. doi: 10.1186/1471-2164-13-424.


Global gene expression analysis of very small embryonic-like stem cells reveals that the Ezh2-dependent bivalent domain mechanism contributes to their pluripotent state.

Shin DM, Liu R, Wu W, Waigel SJ, Zacharias W, Ratajczak MZ, Kucia M.

Stem Cells Dev. 2012 Jul 1;21(10):1639-52. doi: 10.1089/scd.2011.0389. Epub 2012 Jan 4.


OTX2 sustains a bivalent-like state of OTX2-bound promoters in medulloblastoma by maintaining their H3K27me3 levels.

Bunt J, Hasselt NA, Zwijnenburg DA, Koster J, Versteeg R, Kool M.

Acta Neuropathol. 2013 Mar;125(3):385-94. doi: 10.1007/s00401-012-1069-2. Epub 2012 Nov 18.

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