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Results: 1 to 20 of 104

1.

Epigenetic biomarker to determine replicative senescence of cultured cells.

Koch CM, Wagner W.

Methods Mol Biol. 2013;1048:309-21. doi: 10.1007/978-1-62703-556-9_20.

PMID:
23929112
[PubMed - indexed for MEDLINE]
2.

Monitoring of cellular senescence by DNA-methylation at specific CpG sites.

Koch CM, Joussen S, Schellenberg A, Lin Q, Zenke M, Wagner W.

Aging Cell. 2012 Apr;11(2):366-9. doi: 10.1111/j.1474-9726.2011.00784.x. Epub 2012 Jan 19.

PMID:
22221451
[PubMed - indexed for MEDLINE]
3.

Proof of principle: quality control of therapeutic cell preparations using senescence-associated DNA-methylation changes.

Schellenberg A, Mauen S, Koch CM, Jans R, de Waele P, Wagner W.

BMC Res Notes. 2014 Apr 23;7:254. doi: 10.1186/1756-0500-7-254.

PMID:
24755407
[PubMed - in process]
Free PMC Article
4.

DNA methylation pattern changes upon long-term culture and aging of human mesenchymal stromal cells.

Bork S, Pfister S, Witt H, Horn P, Korn B, Ho AD, Wagner W.

Aging Cell. 2010 Feb;9(1):54-63. doi: 10.1111/j.1474-9726.2009.00535.x. Epub 2009 Nov 6.

PMID:
19895632
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

H3K9me-enhanced DNA hypermethylation of the p16INK4a gene: an epigenetic signature for spontaneous transformation of rat mesenchymal stem cells.

Zheng Y, He L, Wan Y, Song J.

Stem Cells Dev. 2013 Jan 15;22(2):256-67. doi: 10.1089/scd.2012.0172. Epub 2012 Nov 7.

PMID:
22873822
[PubMed - indexed for MEDLINE]
6.

The involvement of epigenetic silencing of Foxa2 in cellular replicative and premature senescence induced by hydrogen peroxide.

Zhang W, Ji W, Yang L, Yao L, Wang G, Xuan A, Zhuang Z.

Free Radic Res. 2013 Apr;47(4):325-32. doi: 10.3109/10715762.2013.773589. Epub 2013 Mar 1.

PMID:
23391216
[PubMed - indexed for MEDLINE]
7.

Pluripotent stem cells escape from senescence-associated DNA methylation changes.

Koch CM, Reck K, Shao K, Lin Q, Joussen S, Ziegler P, Walenda G, Drescher W, Opalka B, May T, Brümmendorf T, Zenke M, Saric T, Wagner W.

Genome Res. 2013 Feb;23(2):248-59. doi: 10.1101/gr.141945.112. Epub 2012 Oct 18.

PMID:
23080539
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Replicative senescence of mesenchymal stem cells causes DNA-methylation changes which correlate with repressive histone marks.

Schellenberg A, Lin Q, Schüler H, Koch CM, Joussen S, Denecke B, Walenda G, Pallua N, Suschek CV, Zenke M, Wagner W.

Aging (Albany NY). 2011 Sep;3(9):873-88.

PMID:
22025769
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Epigenetic enhancement of p66Shc during cellular replicative or premature senescence.

Zhang W, Ji W, Yang L, Xu Y, Yang J, Zhuang Z.

Toxicology. 2010 Dec 5;278(2):189-94. doi: 10.1016/j.tox.2010.07.011. Epub 2010 Aug 3.

PMID:
20667496
[PubMed - indexed for MEDLINE]
10.

Dynamics of adipogenic promoter DNA methylation during clonal culture of human adipose stem cells to senescence.

Noer A, Boquest AC, Collas P.

BMC Cell Biol. 2007 May 29;8:18.

PMID:
17535427
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Tracking of replicative senescence in mesenchymal stem cells by colony-forming unit frequency.

Schellenberg A, Hemeda H, Wagner W.

Methods Mol Biol. 2013;976:143-54. doi: 10.1007/978-1-62703-317-6_11.

PMID:
23400440
[PubMed - indexed for MEDLINE]
12.

Comparison of global DNA methylation profiles in replicative versus premature senescence.

Zhang W, Ji W, Yang J, Yang L, Chen W, Zhuang Z.

Life Sci. 2008 Sep 26;83(13-14):475-80. doi: 10.1016/j.lfs.2008.07.015. Epub 2008 Aug 5.

PMID:
18723031
[PubMed - indexed for MEDLINE]
13.

How to track cellular aging of mesenchymal stromal cells?

Wagner W, Bork S, Lepperdinger G, Joussen S, Ma N, Strunk D, Koch C.

Aging (Albany NY). 2010 Apr;2(4):224-30.

PMID:
20453259
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Epigenetic dysregulation in mesenchymal stem cell aging and spontaneous differentiation.

Li Z, Liu C, Xie Z, Song P, Zhao RC, Guo L, Liu Z, Wu Y.

PLoS One. 2011;6(6):e20526. doi: 10.1371/journal.pone.0020526. Epub 2011 Jun 9.

PMID:
21694780
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

[Epigenetic activation of IGF2 during cellular senescence].

Zhang W, Ji W, Yang L, Xu Y, Zhang W, Zhuang Z.

Wei Sheng Yan Jiu. 2010 Jan;39(1):1-3, 8. Chinese.

PMID:
20364576
[PubMed - indexed for MEDLINE]
16.

Specific age-associated DNA methylation changes in human dermal fibroblasts.

Koch CM, Suschek CV, Lin Q, Bork S, Goergens M, Joussen S, Pallua N, Ho AD, Zenke M, Wagner W.

PLoS One. 2011 Feb 8;6(2):e16679. doi: 10.1371/journal.pone.0016679.

PMID:
21347436
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Senescent cells harbour features of the cancer epigenome.

Cruickshanks HA, McBryan T, Nelson DM, Vanderkraats ND, Shah PP, van Tuyn J, Singh Rai T, Brock C, Donahue G, Dunican DS, Drotar ME, Meehan RR, Edwards JR, Berger SL, Adams PD.

Nat Cell Biol. 2013 Dec;15(12):1495-506. doi: 10.1038/ncb2879. Epub 2013 Nov 24.

PMID:
24270890
[PubMed - indexed for MEDLINE]
18.

Confluence-induced alterations in CpG island methylation in cultured normal human fibroblasts.

Pieper RO, Lester KA, Fanton CP.

Nucleic Acids Res. 1999 Aug 1;27(15):3229-35.

PMID:
10454622
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Replicative senescence-associated gene expression changes in mesenchymal stromal cells are similar under different culture conditions.

Schallmoser K, Bartmann C, Rohde E, Bork S, Guelly C, Obenauf AC, Reinisch A, Horn P, Ho AD, Strunk D, Wagner W.

Haematologica. 2010 Jun;95(6):867-74. doi: 10.3324/haematol.2009.011692. Epub 2010 Jan 6.

PMID:
20053868
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Epigenome-wide scans identify differentially methylated regions for age and age-related phenotypes in a healthy ageing population.

Bell JT, Tsai PC, Yang TP, Pidsley R, Nisbet J, Glass D, Mangino M, Zhai G, Zhang F, Valdes A, Shin SY, Dempster EL, Murray RM, Grundberg E, Hedman AK, Nica A, Small KS; MuTHER Consortium, Dermitzakis ET, McCarthy MI, Mill J, Spector TD, Deloukas P.

PLoS Genet. 2012;8(4):e1002629. doi: 10.1371/journal.pgen.1002629. Epub 2012 Apr 19.

PMID:
22532803
[PubMed - indexed for MEDLINE]
Free PMC Article

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