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Similar articles for PubMed (Select 23927004)

1.

Disubstituted 1-aryl-4-aminopiperidine library synthesis using computational drug design and high-throughput batch and flow technologies.

Bryan MC, Hein CD, Gao H, Xia X, Eastwood H, Bruenner BA, Louie SW, Doherty EM.

ACS Comb Sci. 2013 Sep 9;15(9):503-11. doi: 10.1021/co400078r. Epub 2013 Aug 29.

PMID:
23927004
2.

Synthesis of a drug-like focused library of trisubstituted pyrrolidines using integrated flow chemistry and batch methods.

Baumann M, Baxendale IR, Kuratli C, Ley SV, Martin RE, Schneider J.

ACS Comb Sci. 2011 Jul 11;13(4):405-13. doi: 10.1021/co2000357. Epub 2011 May 11.

PMID:
21528880
3.

Editorial: recent trends in library design and virtual screening in medicinal chemistry and drug discovery.

Kumar BV, Sriram D, Yogeeswari P.

Curr Top Med Chem. 2014;14(16):1865. No abstract available.

PMID:
25262807
4.

High impact technologies for natural products screening.

Koehn FE.

Prog Drug Res. 2008;65:175, 177-210. Review.

PMID:
18084916
5.

Design, synthesis and evaluation of benzoisothiazolones as selective inhibitors of PHOSPHO1.

Bravo Y, Teriete P, Dhanya RP, Dahl R, Lee PS, Kiffer-Moreira T, Ganji SR, Sergienko E, Smith LH, Farquharson C, Millán JL, Cosford ND.

Bioorg Med Chem Lett. 2014 Sep 1;24(17):4308-11. doi: 10.1016/j.bmcl.2014.07.013. Epub 2014 Jul 15.

PMID:
25124115
6.

Optimization of three- and four-component reactions for polysubstituted piperidines: application to the synthesis and preliminary biological screening of a prototype library.

Ulaczyk-Lesanko A, Pelletier E, Lee M, Prinz H, Waldmann H, Hall DG.

J Comb Chem. 2007 Jul-Aug;9(4):695-703. Epub 2007 May 24.

PMID:
17521171
7.

Diversity by divergence: Solution-phase parallel synthesis of a library of N-diversified 1-oxa-7-azaspiro[4.5]decan-2-yl-propanes and -butanes.

Kumar S, Thornton PD, Santini C.

ACS Comb Sci. 2013 Nov 11;15(11):564-71. doi: 10.1021/co4001056. Epub 2013 Oct 9.

PMID:
24079459
8.

Solution-phase parallel synthesis of acyclic nucleoside libraries of purine, pyrimidine, and triazole acetamides.

Pathak AK, Pathak V, Reynolds RC.

ACS Comb Sci. 2014 Sep 8;16(9):485-93. doi: 10.1021/co500067c. Epub 2014 Jun 24.

9.

Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis.

Guo T, Shao Y, Qian G, Rokosz LL, Stauffer TM, Hunter RC, Babu SD, Gu H, Hobbs DW.

Bioorg Med Chem Lett. 2005 Aug 15;15(16):3696-700.

PMID:
15978811
10.

Design and synthesis of an aminopiperidine series of γ-secretase modulators.

Kobayashi T, Iwama S, Fusano A, Kato Y, Ikeda A, Teranishi Y, Nishihara A, Tobe M.

Bioorg Med Chem Lett. 2014 Jan 1;24(1):378-81. doi: 10.1016/j.bmcl.2013.10.063. Epub 2013 Nov 6.

PMID:
24269163
11.

Structure-based and property-compliant library design of 11β-HSD1 adamantyl amide inhibitors.

Paderes GD, Dress K, Huang B, Elleraas J, Rejto PA, Pauly T.

Methods Mol Biol. 2011;685:191-215. doi: 10.1007/978-1-60761-931-4_10.

PMID:
20981525
12.

Synthesis of a high-purity chemical library reveals a potent inducer of oxidative stress.

Cui J, Matsumoto K, Wang CY, Peter ME, Kozmin SA.

Chembiochem. 2010 Jun 14;11(9):1224-7. doi: 10.1002/cbic.201000193. No abstract available.

13.

Recent trends and observations in the design of high-quality screening collections.

Renner S, Popov M, Schuffenhauer A, Roth HJ, Breitenstein W, Marzinzik A, Lewis I, Krastel P, Nigsch F, Jenkins J, Jacoby E.

Future Med Chem. 2011 Apr;3(6):751-66. doi: 10.4155/fmc.11.15. Review.

PMID:
21554080
14.

Marine natural product libraries for high-throughput screening and rapid drug discovery.

Bugni TS, Richards B, Bhoite L, Cimbora D, Harper MK, Ireland CM.

J Nat Prod. 2008 Jun;71(6):1095-8. doi: 10.1021/np800184g. Epub 2008 May 28.

15.

Regioselective construction and screening of 1,3-disubstituted tetrahydroindazolones in enantiomerically pure pairs.

Song H, Lee H, Kim J, Park SB.

ACS Comb Sci. 2012 Jan 9;14(1):66-74. doi: 10.1021/co200150d. Epub 2011 Dec 1.

PMID:
22107604
16.

Quinazolindione derivatives as potent 5-HT3A receptor antagonists.

Lee BH, Choi MJ, Jo MN, Seo HJ, Nah SY, Cho YS, Nam G, Pae AN, Rhim H, Choo H.

Bioorg Med Chem. 2009 Jul 1;17(13):4793-6. doi: 10.1016/j.bmc.2009.04.029. Epub 2009 Apr 19.

PMID:
19447040
17.

Fragment-based drug design: computational & experimental state of the art.

Hoffer L, Renaud JP, Horvath D.

Comb Chem High Throughput Screen. 2011 Jul;14(6):500-20. Review.

PMID:
21521152
18.

Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file.

Bell AS, Bradley J, Everett JR, Knight M, Loesel J, Mathias J, McLoughlin D, Mills J, Sharp RE, Williams C, Wood TP.

Mol Divers. 2013 May;17(2):319-35. doi: 10.1007/s11030-013-9438-x. Epub 2013 Apr 5.

PMID:
23559278
19.

The design and synthesis of libraries for the discovery of antibacterial and antifungal substances.

Edwards PJ.

Drug Discov Today. 2011 Mar;16(5-6):278-9. doi: 10.1016/j.drudis.2011.01.010. Epub 2011 Jan 28. No abstract available.

PMID:
21277383
20.

Use of small-molecule crystal structures to address solubility in a novel series of G protein coupled receptor 119 agonists: optimization of a lead and in vivo evaluation.

Scott JS, Birch AM, Brocklehurst KJ, Broo A, Brown HS, Butlin RJ, Clarke DS, Davidsson O, Ertan A, Goldberg K, Groombridge SD, Hudson JA, Laber D, Leach AG, Macfaul PA, McKerrecher D, Pickup A, Schofield P, Svensson PH, Sörme P, Teague J.

J Med Chem. 2012 Jun 14;55(11):5361-79. doi: 10.1021/jm300310c. Epub 2012 May 17.

PMID:
22545772
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