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Results: 1 to 20 of 199

1.

The timing of neural stem cell-based virotherapy is critical for optimal therapeutic efficacy when applied with radiation and chemotherapy for the treatment of glioblastoma.

Tobias AL, Thaci B, Auffinger B, Rincón E, Balyasnikova IV, Kim CK, Han Y, Zhang L, Aboody KS, Ahmed AU, Lesniak MS.

Stem Cells Transl Med. 2013 Sep;2(9):655-66. doi: 10.5966/sctm.2013-0039. Epub 2013 Aug 7.

PMID:
23926209
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

A preclinical evaluation of neural stem cell-based cell carrier for targeted antiglioma oncolytic virotherapy.

Ahmed AU, Thaci B, Tobias AL, Auffinger B, Zhang L, Cheng Y, Kim CK, Yunis C, Han Y, Alexiades NG, Fan X, Aboody KS, Lesniak MS.

J Natl Cancer Inst. 2013 Jul 3;105(13):968-77. doi: 10.1093/jnci/djt141.

PMID:
23821758
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Pharmacokinetic study of neural stem cell-based cell carrier for oncolytic virotherapy: targeted delivery of the therapeutic payload in an orthotopic brain tumor model.

Thaci B, Ahmed AU, Ulasov IV, Tobias AL, Han Y, Aboody KS, Lesniak MS.

Cancer Gene Ther. 2012 Jun;19(6):431-42. doi: 10.1038/cgt.2012.21. Epub 2012 May 4.

PMID:
22555507
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

N-acetylcysteine amide augments the therapeutic effect of neural stem cell-based antiglioma oncolytic virotherapy.

Kim CK, Ahmed AU, Auffinger B, Ulasov IV, Tobias AL, Moon KS, Lesniak MS.

Mol Ther. 2013 Nov;21(11):2063-73. doi: 10.1038/mt.2013.179. Epub 2013 Jul 25.

PMID:
23883863
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma.

Ahmed AU, Tyler MA, Thaci B, Alexiades NG, Han Y, Ulasov IV, Lesniak MS.

Mol Pharm. 2011 Oct 3;8(5):1559-72. doi: 10.1021/mp200161f. Epub 2011 Jun 30.

PMID:
21718006
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Neural stem cell-based cell carriers enhance therapeutic efficacy of an oncolytic adenovirus in an orthotopic mouse model of human glioblastoma.

Ahmed AU, Thaci B, Alexiades NG, Han Y, Qian S, Liu F, Balyasnikova IV, Ulasov IY, Aboody KS, Lesniak MS.

Mol Ther. 2011 Sep;19(9):1714-26. doi: 10.1038/mt.2011.100. Epub 2011 May 31.

PMID:
21629227
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Neural stem cells target intracranial glioma to deliver an oncolytic adenovirus in vivo.

Tyler MA, Ulasov IV, Sonabend AM, Nandi S, Han Y, Marler S, Roth J, Lesniak MS.

Gene Ther. 2009 Feb;16(2):262-78. doi: 10.1038/gt.2008.165. Epub 2008 Dec 11.

PMID:
19078993
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Combination of adenoviral virotherapy and temozolomide chemotherapy eradicates malignant glioma through autophagic and apoptotic cell death in vivo.

Ulasov IV, Sonabend AM, Nandi S, Khramtsov A, Han Y, Lesniak MS.

Br J Cancer. 2009 Apr 7;100(7):1154-64. doi: 10.1038/sj.bjc.6604969. Epub 2009 Mar 10.

PMID:
19277041
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Oncolytic virus-mediated manipulation of DNA damage responses: synergy with chemotherapy in killing glioblastoma stem cells.

Kanai R, Rabkin SD, Yip S, Sgubin D, Zaupa CM, Hirose Y, Louis DN, Wakimoto H, Martuza RL.

J Natl Cancer Inst. 2012 Jan 4;104(1):42-55. doi: 10.1093/jnci/djr509. Epub 2011 Dec 15.

PMID:
22173583
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

CRAdRGDflt-IL24 virotherapy in combination with chemotherapy of experimental glioma.

Kaliberova LN, Krendelchtchikova V, Harmon DK, Stockard CR, Petersen AS, Markert JM, Gillespie GY, Grizzle WE, Buchsbaum DJ, Kaliberov SA.

Cancer Gene Ther. 2009 Oct;16(10):794-805. doi: 10.1038/cgt.2009.23. Epub 2009 Apr 10.

PMID:
19363468
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Double suicide gene therapy using human neural stem cells against glioblastoma: double safety measures.

Lee JY, Lee DH, Kim HA, Choi SA, Lee HJ, Park CK, Phi JH, Wang KC, Kim SU, Kim SK.

J Neurooncol. 2014 Jan;116(1):49-57. doi: 10.1007/s11060-013-1264-6. Epub 2013 Oct 11.

PMID:
24113876
[PubMed - indexed for MEDLINE]
12.

Enhanced antitumor efficacy of low-dose Etoposide with oncolytic herpes simplex virus in human glioblastoma stem cell xenografts.

Cheema TA, Kanai R, Kim GW, Wakimoto H, Passer B, Rabkin SD, Martuza RL.

Clin Cancer Res. 2011 Dec 1;17(23):7383-93. doi: 10.1158/1078-0432.CCR-11-1762. Epub 2011 Oct 5.

PMID:
21976549
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model.

Huang TT, Hlavaty J, Ostertag D, Espinoza FL, Martin B, Petznek H, Rodriguez-Aguirre M, Ibañez CE, Kasahara N, Gunzburg W, Gruber HE, Pertschuk D, Jolly DJ, Robbins JM.

Cancer Gene Ther. 2013 Oct;20(10):544-51. doi: 10.1038/cgt.2013.51. Epub 2013 Aug 23.

PMID:
23969884
[PubMed - indexed for MEDLINE]
14.

Neural stem cell-mediated delivery of irinotecan-activating carboxylesterases to glioma: implications for clinical use.

Metz MZ, Gutova M, Lacey SF, Abramyants Y, Vo T, Gilchrist M, Tirughana R, Ghoda LY, Barish ME, Brown CE, Najbauer J, Potter PM, Portnow J, Synold TW, Aboody KS.

Stem Cells Transl Med. 2013 Dec;2(12):983-92. doi: 10.5966/sctm.2012-0177. Epub 2013 Oct 28.

PMID:
24167321
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Long-term in vitro treatment of human glioblastoma cells with temozolomide increases resistance in vivo through up-regulation of GLUT transporter and aldo-keto reductase enzyme AKR1C expression.

Le Calvé B, Rynkowski M, Le Mercier M, Bruyère C, Lonez C, Gras T, Haibe-Kains B, Bontempi G, Decaestecker C, Ruysschaert JM, Kiss R, Lefranc F.

Neoplasia. 2010 Sep;12(9):727-39. Erratum in: Neoplasia. 2011 Sep;13(9):5 p following 886.

PMID:
20824049
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Transcriptional targeting of adenovirally delivered tumor necrosis factor alpha by temozolomide in experimental glioblastoma.

Yamini B, Yu X, Gillespie GY, Kufe DW, Weichselbaum RR.

Cancer Res. 2004 Sep 15;64(18):6381-4.

PMID:
15374943
[PubMed - indexed for MEDLINE]
Free Article
17.

YB-1 dependent oncolytic adenovirus efficiently inhibits tumor growth of glioma cancer stem like cells.

Mantwill K, Naumann U, Seznec J, Girbinger V, Lage H, Surowiak P, Beier D, Mittelbronn M, Schlegel J, Holm PS.

J Transl Med. 2013 Sep 18;11:216. doi: 10.1186/1479-5876-11-216.

PMID:
24044901
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Survivin-driven and fiber-modified oncolytic adenovirus exhibits potent antitumor activity in established intracranial glioma.

Ulasov IV, Zhu ZB, Tyler MA, Han Y, Rivera AA, Khramtsov A, Curiel DT, Lesniak MS.

Hum Gene Ther. 2007 Jul;18(7):589-602.

PMID:
17630837
[PubMed - indexed for MEDLINE]
19.

Low-dose radiation enhances survivin-mediated virotherapy against malignant glioma stem cells.

Nandi S, Ulasov IV, Tyler MA, Sugihara AQ, Molinero L, Han Y, Zhu ZB, Lesniak MS.

Cancer Res. 2008 Jul 15;68(14):5778-84. doi: 10.1158/0008-5472.CAN-07-6441.

PMID:
18632631
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Inhibition of MMP14 potentiates the therapeutic effect of temozolomide and radiation in gliomas.

Ulasov I, Thaci B, Sarvaiya P, Yi R, Guo D, Auffinger B, Pytel P, Zhang L, Kim CK, Borovjagin A, Dey M, Han Y, Baryshnikov AY, Lesniak MS.

Cancer Med. 2013 Aug;2(4):457-67. doi: 10.1002/cam4.104. Epub 2013 Jun 30.

PMID:
24156018
[PubMed - indexed for MEDLINE]
Free PMC Article
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