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Items: 1 to 20 of 156

1.

Design and synthesis of 4-alkyl-2-amino(acetamino)-6-aryl-1,3-thiazine derivatives as influenza neuraminidase inhibitors.

Li W, Xia L, Hu A, Liu A, Peng J, Tan W.

Arch Pharm (Weinheim). 2013 Sep;346(9):635-44. doi: 10.1002/ardp.201300122. Epub 2013 Aug 7.

PMID:
23926081
2.

Synthesis of acylguanidine zanamivir derivatives as neuraminidase inhibitors and the evaluation of their bio-activities.

Lin CH, Chang TC, Das A, Fang MY, Hung HC, Hsu KC, Yang JM, von Itzstein M, Mong KK, Hsu TA, Lin CC.

Org Biomol Chem. 2013 Jun 28;11(24):3943-8. doi: 10.1039/c3ob40624e.

PMID:
23695381
3.

Design, synthesis, and biological activity of thiazole derivatives as novel influenza neuraminidase inhibitors.

Liu Y, Zhang L, Gong J, Fang H, Liu A, Du G, Xu W.

J Enzyme Inhib Med Chem. 2011 Aug;26(4):506-13. doi: 10.3109/14756366.2010.534732. Epub 2010 Dec 14.

PMID:
21143042
4.

3D QSAR and docking study of flavone derivatives as potent inhibitors of influenza H1N1 virus neuraminidase.

Gao L, Zu M, Wu S, Liu AL, Du GH.

Bioorg Med Chem Lett. 2011 Oct 1;21(19):5964-70. doi: 10.1016/j.bmcl.2011.07.071. Epub 2011 Jul 26.

PMID:
21843936
5.

Studies on synthesis and structure-activity relationship (SAR) of derivatives of a new natural product from marine fungi as inhibitors of influenza virus neuraminidase.

Li J, Zhang D, Zhu X, He Z, Liu S, Li M, Pang J, Lin Y.

Mar Drugs. 2011;9(10):1887-901. doi: 10.3390/md9101887. Epub 2011 Oct 11.

6.

Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: the hydrophobic side chain influences type A subtype selectivity.

Li Y, Silamkoti A, Kolavi G, Mou L, Gulati S, Air GM, Brouillette WJ.

Bioorg Med Chem. 2012 Jul 15;20(14):4582-9. doi: 10.1016/j.bmc.2012.05.001. Epub 2012 May 17.

7.

Insights from investigating the interaction of oseltamivir (Tamiflu) with neuraminidase of the 2009 H1N1 swine flu virus.

Wang SQ, Du QS, Huang RB, Zhang DW, Chou KC.

Biochem Biophys Res Commun. 2009 Aug 28;386(3):432-6. doi: 10.1016/j.bbrc.2009.06.016. Epub 2009 Jun 10.

PMID:
19523442
8.

Evaluation of the anti-neuraminidase activity of the traditional Chinese medicines and determination of the anti-influenza A virus effects of the neuraminidase inhibitory TCMs in vitro and in vivo.

Tian L, Wang Z, Wu H, Wang S, Wang Y, Wang Y, Xu J, Wang L, Qi F, Fang M, Yu D, Fang X.

J Ethnopharmacol. 2011 Sep 1;137(1):534-42. doi: 10.1016/j.jep.2011.06.002. Epub 2011 Jun 12.

PMID:
21699971
9.

Design and synthesis of benzoic acid derivatives as influenza neuraminidase inhibitors using structure-based drug design.

Chand P, Babu YS, Bantia S, Chu N, Cole LB, Kotian PL, Laver WG, Montgomery JA, Pathak VP, Petty SL, Shrout DP, Walsh DA, Walsh GM.

J Med Chem. 1997 Dec 5;40(25):4030-52.

PMID:
9406595
10.

Oseltamivir hydroxamate and acyl sulfonamide derivatives as influenza neuraminidase inhibitors.

Hong BT, Chen CL, Fang JM, Tsai KC, Wang SY, Huang WI, Cheng YS, Wong CH.

Bioorg Med Chem. 2014 Dec 1;22(23):6647-54.

PMID:
25456388
11.

Carbocyclic influenza neuraminidase inhibitors possessing a C3-cyclic amine side chain: synthesis and inhibitory activity.

Lew W, Wu H, Chen X, Graves BJ, Escarpe PA, MacArthur HL, Mendel DB, Kim CU.

Bioorg Med Chem Lett. 2000 Jun 5;10(11):1257-60.

PMID:
10866394
12.

Discovery of N-substituted oseltamivir derivatives as potent and selective inhibitors of H5N1 influenza neuraminidase.

Xie Y, Xu D, Huang B, Ma X, Qi W, Shi F, Liu X, Zhang Y, Xu W.

J Med Chem. 2014 Oct 23;57(20):8445-58. doi: 10.1021/jm500892k. Epub 2014 Oct 8.

PMID:
25255388
13.

Recent progress and challenges in the discovery of new neuraminidase inhibitors.

Chamni S, De-Eknamkul W.

Expert Opin Ther Pat. 2013 Apr;23(4):409-23. doi: 10.1517/13543776.2013.765861. Epub 2013 Feb 1. Review.

PMID:
23369206
14.

In vitro antiviral effects and 3D QSAR study of resveratrol derivatives as potent inhibitors of influenza H1N1 neuraminidase.

Li C, Fang JS, Lian WW, Pang XC, Liu AL, Du GH.

Chem Biol Drug Des. 2015 Apr;85(4):427-38. doi: 10.1111/cbdd.12425. Epub 2014 Sep 29.

PMID:
25185493
15.

Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors.

Liu Y, Jing F, Xu Y, Xie Y, Shi F, Fang H, Li M, Xu W.

Bioorg Med Chem. 2011 Apr 1;19(7):2342-8. doi: 10.1016/j.bmc.2011.02.019. Epub 2011 Feb 17.

PMID:
21382719
16.

Design, synthesis, and anti-influenza viral activities of 1,3-diarylprop-2-en-1-ones: a novel class of neuraminidase inhibitors.

Kinger M, Park YD, Park JH, Hur MG, Jeong HJ, Park SJ, Lee WS, Kim SW, Yang SD.

Arch Pharm Res. 2012 Mar;35(4):633-8. doi: 10.1007/s12272-012-0406-2. Epub 2012 May 3.

PMID:
22553055
17.

Further discovery of caffeic acid derivatives as novel influenza neuraminidase inhibitors.

Xie Y, Huang B, Yu K, Xu W.

Bioorg Med Chem. 2013 Dec 15;21(24):7715-23. doi: 10.1016/j.bmc.2013.10.020. Epub 2013 Oct 26.

PMID:
24262883
18.

Structure-activity relationship studies of novel carbocyclic influenza neuraminidase inhibitors.

Kim CU, Lew W, Williams MA, Wu H, Zhang L, Chen X, Escarpe PA, Mendel DB, Laver WG, Stevens RC.

J Med Chem. 1998 Jul 2;41(14):2451-60.

PMID:
9651151
19.

Systematic structure-based design and stereoselective synthesis of novel multisubstituted cyclopentane derivatives with potent antiinfluenza activity.

Chand P, Kotian PL, Dehghani A, El-Kattan Y, Lin TH, Hutchison TL, Babu YS, Bantia S, Elliott AJ, Montgomery JA.

J Med Chem. 2001 Dec 6;44(25):4379-92.

PMID:
11728184
20.

BCX-1812 (RWJ-270201): discovery of a novel, highly potent, orally active, and selective influenza neuraminidase inhibitor through structure-based drug design.

Babu YS, Chand P, Bantia S, Kotian P, Dehghani A, El-Kattan Y, Lin TH, Hutchison TL, Elliott AJ, Parker CD, Ananth SL, Horn LL, Laver GW, Montgomery JA.

J Med Chem. 2000 Sep 21;43(19):3482-6. No abstract available.

PMID:
11000002
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