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Items: 1 to 20 of 102

1.

High content screening as high quality assay for biological evaluation of photosensitizers in vitro.

Vaz GM, Paszko E, Davies AM, Senge MO.

PLoS One. 2013 Jul 29;8(7):e70653. doi: 10.1371/journal.pone.0070653. Print 2013.

2.

Comparison between 5,10,15,20-tetraaryl- and 5,15-diarylporphyrins as photosensitizers: synthesis, photodynamic activity, and quantitative structure-activity relationship modeling.

Banfi S, Caruso E, Buccafurni L, Murano R, Monti E, Gariboldi M, Papa E, Gramatica P.

J Med Chem. 2006 Jun 1;49(11):3293-304.

PMID:
16722648
3.

High-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markers.

Martin HL, Adams M, Higgins J, Bond J, Morrison EE, Bell SM, Warriner S, Nelson A, Tomlinson DC.

PLoS One. 2014 Feb 5;9(2):e88338. doi: 10.1371/journal.pone.0088338. eCollection 2014.

4.

A 1536-well quantitative high-throughput screen to identify compounds targeting cancer stem cells.

Mathews LA, Keller JM, Goodwin BL, Guha R, Shinn P, Mull R, Thomas CJ, de Kluyver RL, Sayers TJ, Ferrer M.

J Biomol Screen. 2012 Oct;17(9):1231-42. Epub 2012 Aug 27.

PMID:
22927676
5.

Affinity-based screening techniques: their impact and benefit to increase the number of high quality leads.

Bergsdorf C, Ottl J.

Expert Opin Drug Discov. 2010 Nov;5(11):1095-107. doi: 10.1517/17460441.2010.524641. Epub 2010 Oct 7. Review.

PMID:
22827747
6.

Porphyrin and nonporphyrin photosensitizers in oncology: preclinical and clinical advances in photodynamic therapy.

O'Connor AE, Gallagher WM, Byrne AT.

Photochem Photobiol. 2009 Sep-Oct;85(5):1053-74. doi: 10.1111/j.1751-1097.2009.00585.x. Epub 2009 Aug 3. Review.

PMID:
19682322
7.

Implementation of a 220,000-compound HCS campaign to identify disruptors of the interaction between p53 and hDM2 and characterization of the confirmed hits.

Dudgeon DD, Shinde S, Hua Y, Shun TY, Lazo JS, Strock CJ, Giuliano KA, Taylor DL, Johnston PA, Johnston PA.

J Biomol Screen. 2010 Aug;15(7):766-82. doi: 10.1177/1087057110375304. Epub 2010 Jul 16.

PMID:
20639499
8.

Photodynamic effects of porphyrin and chlorin photosensitizers in human colon adenocarcinoma cells.

Banfi S, Caruso E, Caprioli S, Mazzagatti L, Canti G, Ravizza R, Gariboldi M, Monti E.

Bioorg Med Chem. 2004 Sep 15;12(18):4853-60.

PMID:
15336264
9.

A novel imaging-based high-throughput screening approach to anti-angiogenic drug discovery.

Evensen L, Micklem DR, Link W, Lorens JB.

Cytometry A. 2010 Jan;77(1):41-51. doi: 10.1002/cyto.a.20808.

10.

Systems biology approach for in vivo photodynamic therapy optimization of ruthenium-porphyrin compounds.

Pernot M, Bastogne T, Barry NP, Therrien B, Koellensperger G, Hann S, Reshetov V, Barberi-Heyob M.

J Photochem Photobiol B. 2012 Dec 5;117:80-9. doi: 10.1016/j.jphotobiol.2012.08.012. Epub 2012 Sep 28.

PMID:
23085627
11.

Synthesis and in vitro photodynamic activities of water-soluble fluorinated tetrapyridylporphyrins as tumor photosensitizers.

Ko YJ, Yun KJ, Kang MS, Park J, Lee KT, Park SB, Shin JH.

Bioorg Med Chem Lett. 2007 May 15;17(10):2789-94. Epub 2007 Mar 12.

PMID:
17383879
12.

Development of a high-content screening assay panel to accelerate mechanism of action studies for oncology research.

Towne DL, Nicholl EE, Comess KM, Galasinski SC, Hajduk PJ, Abraham VC.

J Biomol Screen. 2012 Sep;17(8):1005-17. doi: 10.1177/1087057112450050. Epub 2012 Jun 15.

PMID:
22706350
13.

Porphyrin-carbohydrate conjugates: impact of carbohydrate moieties in photodynamic therapy (PDT).

Zheng X, Pandey RK.

Anticancer Agents Med Chem. 2008 Apr;8(3):241-68. Review.

PMID:
18393785
14.

Breast cancer resistant protein (BCRP) is a molecular determinant of the outcome of photodynamic therapy (PDT) for centrally located early lung cancer.

Usuda J, Tsunoda Y, Ichinose S, Ishizumi T, Ohtani K, Maehara S, Ono S, Tsutsui H, Ohira T, Okunaka T, Furukawa K, Sugimoto Y, Kato H, Ikeda N.

Lung Cancer. 2010 Feb;67(2):198-204. doi: 10.1016/j.lungcan.2009.04.002. Epub 2009 May 23.

PMID:
19477032
15.

A novel small molecule target in human airway smooth muscle for potential treatment of obstructive lung diseases: a staged high-throughput biophysical screening.

An SS, Askovich PS, Zarembinski TI, Ahn K, Peltier JM, von Rechenberg M, Sahasrabudhe S, Fredberg JJ.

Respir Res. 2011 Jan 13;12:8. doi: 10.1186/1465-9921-12-8.

16.

Ruthenium porphyrin compounds for photodynamic therapy of cancer.

Schmitt F, Govindaswamy P, Süss-Fink G, Ang WH, Dyson PJ, Juillerat-Jeanneret L, Therrien B.

J Med Chem. 2008 Mar 27;51(6):1811-6. doi: 10.1021/jm701382p. Epub 2008 Feb 26.

PMID:
18298056
17.

Design, synthesis, and biological evaluation of folic acid targeted tetraphenylporphyrin as novel photosensitizers for selective photodynamic therapy.

Schneider R, Schmitt F, Frochot C, Fort Y, Lourette N, Guillemin F, Müller JF, Barberi-Heyob M.

Bioorg Med Chem. 2005 Apr 15;13(8):2799-808.

PMID:
15781391
18.

A high-throughput biophotonics instrument to screen for novel ocular photosensitizing therapeutic agents.

Butler MC, Itotia PN, Sullivan JM.

Invest Ophthalmol Vis Sci. 2010 May;51(5):2705-20. doi: 10.1167/iovs.08-2862. Epub 2009 Oct 15.

19.

An image-based, high-throughput screening assay for molecules that induce excess DNA replication in human cancer cells.

Zhu W, Lee CY, Johnson RL, Wichterman J, Huang R, DePamphilis ML.

Mol Cancer Res. 2011 Mar;9(3):294-310. doi: 10.1158/1541-7786.MCR-10-0570. Epub 2011 Jan 21. Erratum in: Mol Cancer Res. 2011 Jul;9(7):976.

20.

Profile-QSAR: a novel meta-QSAR method that combines activities across the kinase family to accurately predict affinity, selectivity, and cellular activity.

Martin E, Mukherjee P, Sullivan D, Jansen J.

J Chem Inf Model. 2011 Aug 22;51(8):1942-56. doi: 10.1021/ci1005004. Epub 2011 Jul 19.

PMID:
21667971
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