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Nicotinamide phosphoribosyl transferase (Nampt) is a target of microRNA-26b in colorectal cancer cells.

Zhang C, Tong J, Huang G.

PLoS One. 2013 Jul 29;8(7):e69963. doi: 10.1371/journal.pone.0069963. Print 2013.


Elevated microRNA-34a in obesity reduces NAD+ levels and SIRT1 activity by directly targeting NAMPT.

Choi SE, Fu T, Seok S, Kim DH, Yu E, Lee KW, Kang Y, Li X, Kemper B, Kemper JK.

Aging Cell. 2013 Dec;12(6):1062-72. doi: 10.1111/acel.12135. Epub 2013 Aug 11.


Human embryonic stem cells and metastatic colorectal cancer cells shared the common endogenous human microRNA-26b.

Ma YL, Zhang P, Wang F, Moyer MP, Yang JJ, Liu ZH, Peng JY, Chen HQ, Zhou YK, Liu WJ, Qin HL.

J Cell Mol Med. 2011 Sep;15(9):1941-54. doi: 10.1111/j.1582-4934.2010.01170.x.


Down-regulation of NAMPT expression by miR-182 is involved in Tat-induced HIV-1 long terminal repeat (LTR) transactivation.

Chen XY, Zhang HS, Wu TC, Sang WW, Ruan Z.

Int J Biochem Cell Biol. 2013 Feb;45(2):292-8. doi: 10.1016/j.biocel.2012.11.002. Epub 2012 Nov 12.


MicroRNA-218 inhibits cell cycle progression and promotes apoptosis in colon cancer by downregulating BMI1 polycomb ring finger oncogene.

He X, Dong Y, Wu CW, Zhao Z, Ng SS, Chan FK, Sung JJ, Yu J.

Mol Med. 2013 Feb 8;18:1491-8. doi: 10.2119/molmed.2012.00304.


Endogenous NAMPT dampens chemokine expression and apoptotic responses in stressed tubular cells.

Benito-Martin A, Ucero AC, Izquierdo MC, Santamaria B, Picatoste B, Carrasco S, Lorenzo O, Ruiz-Ortega M, Egido J, Ortiz A.

Biochim Biophys Acta. 2014 Feb;1842(2):293-303. doi: 10.1016/j.bbadis.2013.11.022. Epub 2013 Nov 25.


Genetic and epigenetic down-regulation of microRNA-212 promotes colorectal tumor metastasis via dysregulation of MnSOD.

Meng X, Wu J, Pan C, Wang H, Ying X, Zhou Y, Yu H, Zuo Y, Pan Z, Liu RY, Huang W.

Gastroenterology. 2013 Aug;145(2):426-36.e1-6. doi: 10.1053/j.gastro.2013.04.004. Epub 2013 Apr 9.


miR-133a represses tumour growth and metastasis in colorectal cancer by targeting LIM and SH3 protein 1 and inhibiting the MAPK pathway.

Wang H, An H, Wang B, Liao Q, Li W, Jin X, Cui S, Zhang Y, Ding Y, Zhao L.

Eur J Cancer. 2013 Dec;49(18):3924-35. doi: 10.1016/j.ejca.2013.07.149. Epub 2013 Aug 19.


MicroRNA-221 promotes colorectal cancer cell invasion and metastasis by targeting RECK.

Qin J, Luo M.

FEBS Lett. 2014 Jan 3;588(1):99-104. doi: 10.1016/j.febslet.2013.11.014. Epub 2013 Nov 20.


microRNA-7 is a novel inhibitor of YY1 contributing to colorectal tumorigenesis.

Zhang N, Li X, Wu CW, Dong Y, Cai M, Mok MT, Wang H, Chen J, Ng SS, Chen M, Sung JJ, Yu J.

Oncogene. 2013 Oct 17;32(42):5078-88. doi: 10.1038/onc.2012.526. Epub 2012 Dec 3.


MicroRNA-124 regulates the proliferation of colorectal cancer cells by targeting iASPP.

Liu K, Zhao H, Yao H, Lei S, Lei Z, Li T, Qi H.

Biomed Res Int. 2013;2013:867537. doi: 10.1155/2013/867537. Epub 2013 Apr 10.


miR-137 targets Cdc42 expression, induces cell cycle G1 arrest and inhibits invasion in colorectal cancer cells.

Liu M, Lang N, Qiu M, Xu F, Li Q, Tang Q, Chen J, Chen X, Zhang S, Liu Z, Zhou J, Zhu Y, Deng Y, Zheng Y, Bi F.

Int J Cancer. 2011 Mar 15;128(6):1269-79. doi: 10.1002/ijc.25452.


Nicotinamide phosphoribosyltransferase: a potent therapeutic target in non-small cell lung cancer with epidermal growth factor receptor-gene mutation.

Okumura S, Sasaki T, Minami Y, Ohsaki Y.

J Thorac Oncol. 2012 Jan;7(1):49-56. doi: 10.1097/JTO.0b013e318233d686.


Overexpression of Nampt in gastric cancer and chemopotentiating effects of the Nampt inhibitor FK866 in combination with fluorouracil.

Bi TQ, Che XM, Liao XH, Zhang DJ, Long HL, Li HJ, Zhao W.

Oncol Rep. 2011 Nov;26(5):1251-7. doi: 10.3892/or.2011.1378. Epub 2011 Jul 4.


miR-185 targets RhoA and Cdc42 expression and inhibits the proliferation potential of human colorectal cells.

Liu M, Lang N, Chen X, Tang Q, Liu S, Huang J, Zheng Y, Bi F.

Cancer Lett. 2011 Feb 28;301(2):151-60. doi: 10.1016/j.canlet.2010.11.009. Epub 2010 Dec 24.


MicroRNA-26b is underexpressed in human breast cancer and induces cell apoptosis by targeting SLC7A11.

Liu XX, Li XJ, Zhang B, Liang YJ, Zhou CX, Cao DX, He M, Chen GQ, He JR, Zhao Q.

FEBS Lett. 2011 May 6;585(9):1363-7. doi: 10.1016/j.febslet.2011.04.018. Epub 2011 Apr 14.


MicroRNA-137, an HMGA1 target, suppresses colorectal cancer cell invasion and metastasis in mice by directly targeting FMNL2.

Liang L, Li X, Zhang X, Lv Z, He G, Zhao W, Ren X, Li Y, Bian X, Liao W, Liu W, Yang G, Ding Y.

Gastroenterology. 2013 Mar;144(3):624-635.e4. doi: 10.1053/j.gastro.2012.11.033. Epub 2012 Nov 27.


MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer.

Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S, Allgayer H.

Oncogene. 2008 Apr 3;27(15):2128-36. Epub 2007 Oct 29.


MicroRNA-32 (miR-32) regulates phosphatase and tensin homologue (PTEN) expression and promotes growth, migration, and invasion in colorectal carcinoma cells.

Wu W, Yang J, Feng X, Wang H, Ye S, Yang P, Tan W, Wei G, Zhou Y.

Mol Cancer. 2013 Apr 23;12:30. doi: 10.1186/1476-4598-12-30.


CD73 protein as a source of extracellular precursors for sustained NAD+ biosynthesis in FK866-treated tumor cells.

Grozio A, Sociali G, Sturla L, Caffa I, Soncini D, Salis A, Raffaelli N, De Flora A, Nencioni A, Bruzzone S.

J Biol Chem. 2013 Sep 6;288(36):25938-49. doi: 10.1074/jbc.M113.470435. Epub 2013 Jul 23.

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