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Results: 1 to 20 of 226

1.

Morphoproteomic profiling of the mammalian target of rapamycin (mTOR) signaling pathway in desmoplastic small round cell tumor (EWS/WT1), Ewing's sarcoma (EWS/FLI1) and Wilms' tumor(WT1).

Subbiah V, Brown RE, Jiang Y, Buryanek J, Hayes-Jordan A, Kurzrock R, Anderson PM.

PLoS One. 2013 Jul 29;8(7):e68985. doi: 10.1371/journal.pone.0068985. Print 2013.

PMID:
23922674
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Targeted morphoproteomic profiling of Ewing's sarcoma treated with insulin-like growth factor 1 receptor (IGF1R) inhibitors: response/resistance signatures.

Subbiah V, Naing A, Brown RE, Chen H, Doyle L, LoRusso P, Benjamin R, Anderson P, Kurzrock R.

PLoS One. 2011 Apr 6;6(4):e18424. doi: 10.1371/journal.pone.0018424.

PMID:
21494688
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesis.

Leacock SW, Basse AN, Chandler GL, Kirk AM, Rakheja D, Amatruda JF.

Dis Model Mech. 2012 Jan;5(1):95-106. doi: 10.1242/dmm.007401. Epub 2011 Oct 6.

PMID:
21979944
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

R1507, an anti-insulin-like growth factor-1 receptor (IGF-1R) antibody, and EWS/FLI-1 siRNA in Ewing's sarcoma: convergence at the IGF/IGFR/Akt axis.

Huang HJ, Angelo LS, Rodon J, Sun M, Kuenkele KP, Parsons HA, Trent JC, Kurzrock R.

PLoS One. 2011;6(10):e26060. doi: 10.1371/journal.pone.0026060. Epub 2011 Oct 11.

PMID:
22022506
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

A tetraspanin-family protein, T-cell acute lymphoblastic leukemia-associated antigen 1, is induced by the Ewing's sarcoma-Wilms' tumor 1 fusion protein of desmoplastic small round-cell tumor.

Ito E, Honma R, Imai J, Azuma S, Kanno T, Mori S, Yoshie O, Nishio J, Iwasaki H, Yoshida K, Gohda J, Inoue J, Watanabe S, Semba K.

Am J Pathol. 2003 Dec;163(6):2165-72.

PMID:
14633590
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

WT1 staining reliably differentiates desmoplastic small round cell tumor from Ewing sarcoma/primitive neuroectodermal tumor. An immunohistochemical and molecular diagnostic study.

Hill DA, Pfeifer JD, Marley EF, Dehner LP, Humphrey PA, Zhu X, Swanson PE.

Am J Clin Pathol. 2000 Sep;114(3):345-53.

PMID:
10989634
[PubMed - indexed for MEDLINE]
Free Article
7.

Junction region of EWS-FLI1 fusion protein has a dominant negative effect in Ewing's sarcoma in vitro.

Jully B, Vijayalakshmi R, Gopal G, Sabitha K, Rajkumar T.

BMC Cancer. 2012 Nov 12;12:513. doi: 10.1186/1471-2407-12-513.

PMID:
23145994
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma.

Boro A, Prêtre K, Rechfeld F, Thalhammer V, Oesch S, Wachtel M, Schäfer BW, Niggli FK.

Int J Cancer. 2012 Nov 1;131(9):2153-64. doi: 10.1002/ijc.27472. Epub 2012 Mar 29.

PMID:
22323082
[PubMed - indexed for MEDLINE]
9.

High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition.

Awad O, Yustein JT, Shah P, Gul N, Katuri V, O'Neill A, Kong Y, Brown ML, Toretsky JA, Loeb DM.

PLoS One. 2010 Nov 11;5(11):e13943. doi: 10.1371/journal.pone.0013943.

PMID:
21085683
[PubMed - indexed for MEDLINE]
Free PMC Article
10.
11.

Molecular heterogeneity and function of EWS-WT1 fusion transcripts in desmoplastic small round cell tumors.

Liu J, Nau MM, Yeh JC, Allegra CJ, Chu E, Wright JJ.

Clin Cancer Res. 2000 Sep;6(9):3522-9.

PMID:
10999739
[PubMed - indexed for MEDLINE]
Free Article
12.

Phosphorylation of Ewing's sarcoma protein (EWS) and EWS-Fli1 in response to DNA damage.

Klevernic IV, Morton S, Davis RJ, Cohen P.

Biochem J. 2009 Mar 15;418(3):625-34. doi: 10.1042/BJ20082097.

PMID:
19076070
[PubMed - indexed for MEDLINE]
Free Article
13.

Interference with the constitutive activation of ERK1 and ERK2 impairs EWS/FLI-1-dependent transformation.

Silvany RE, Eliazer S, Wolff NC, Ilaria RL Jr.

Oncogene. 2000 Sep 14;19(39):4523-30.

PMID:
11002425
[PubMed - indexed for MEDLINE]
Free Article
14.

The evaluation of CD99 immunoreactivity and EWS/FLI1 translocation by fluorescence in situ hybridization in central PNETs and Ewing's sarcoma family of tumors.

Vural C, Uluoğlu O, Akyürek N, Oğuz A, Karadeniz C.

Pathol Oncol Res. 2011 Sep;17(3):619-25. doi: 10.1007/s12253-010-9358-3. Epub 2011 Jan 26.

PMID:
21267687
[PubMed - indexed for MEDLINE]
15.

Morphoproteomic profile of mTOR, Ras/Raf kinase/ERK, and NF-kappaB pathways in human gastric adenocarcinoma.

Feng W, Brown RE, Trung CD, Li W, Wang L, Khoury T, Alrawi S, Yao J, Xia K, Tan D.

Ann Clin Lab Sci. 2008 Summer;38(3):195-209.

PMID:
18715846
[PubMed - indexed for MEDLINE]
16.

Fusion of the EWS and WT1 genes in the desmoplastic small round cell tumor.

Ladanyi M, Gerald W.

Cancer Res. 1994 Jun 1;54(11):2837-40.

PMID:
8187063
[PubMed - indexed for MEDLINE]
Free Article
17.

FOXO1 is a direct target of EWS-Fli1 oncogenic fusion protein in Ewing's sarcoma cells.

Yang L, Hu HM, Zielinska-Kwiatkowska A, Chansky HA.

Biochem Biophys Res Commun. 2010 Nov 5;402(1):129-34. doi: 10.1016/j.bbrc.2010.09.129. Epub 2010 Oct 8.

PMID:
20933505
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A novel oncogenic mechanism in Ewing sarcoma involving IGF pathway targeting by EWS/Fli1-regulated microRNAs.

McKinsey EL, Parrish JK, Irwin AE, Niemeyer BF, Kern HB, Birks DK, Jedlicka P.

Oncogene. 2011 Dec 8;30(49):4910-20. doi: 10.1038/onc.2011.197. Epub 2011 Jun 6.

PMID:
21643012
[PubMed - indexed for MEDLINE]
19.

EWS/FLI and its downstream target NR0B1 interact directly to modulate transcription and oncogenesis in Ewing's sarcoma.

Kinsey M, Smith R, Iyer AK, McCabe ER, Lessnick SL.

Cancer Res. 2009 Dec 1;69(23):9047-55. doi: 10.1158/0008-5472.CAN-09-1540. Epub 2009 Nov 17.

PMID:
19920188
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Promiscuous partnerships in Ewing's sarcoma.

Sankar S, Lessnick SL.

Cancer Genet. 2011 Jul;204(7):351-65. doi: 10.1016/j.cancergen.2011.07.008. Review.

PMID:
21872822
[PubMed - indexed for MEDLINE]
Free PMC Article

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