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Results: 1 to 20 of 92

1.

Histone deacetylase 3 as a novel therapeutic target in multiple myeloma.

Minami J, Suzuki R, Mazitschek R, Gorgun G, Ghosh B, Cirstea D, Hu Y, Mimura N, Ohguchi H, Cottini F, Jakubikova J, Munshi NC, Haggarty SJ, Richardson PG, Hideshima T, Anderson KC.

Leukemia. 2014 Mar;28(3):680-9. doi: 10.1038/leu.2013.231. Epub 2013 Aug 5.

PMID:
23913134
[PubMed - indexed for MEDLINE]
2.

Histone deacetylases are critical targets of bortezomib-induced cytotoxicity in multiple myeloma.

Kikuchi J, Wada T, Shimizu R, Izumi T, Akutsu M, Mitsunaga K, Noborio-Hatano K, Nobuyoshi M, Ozawa K, Kano Y, Furukawa Y.

Blood. 2010 Jul 22;116(3):406-17. doi: 10.1182/blood-2009-07-235663. Epub 2010 Mar 29.

PMID:
20351311
[PubMed - indexed for MEDLINE]
Free Article
3.

The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.

Kikuchi J, Yamada S, Koyama D, Wada T, Nobuyoshi M, Izumi T, Akutsu M, Kano Y, Furukawa Y.

J Biol Chem. 2013 Aug 30;288(35):25593-602. doi: 10.1074/jbc.M113.480574. Epub 2013 Jul 22.

PMID:
23878197
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Histone deacetylase inhibitors in the treatment for multiple myeloma.

Hideshima T, Anderson KC.

Int J Hematol. 2013 Mar;97(3):324-32. doi: 10.1007/s12185-013-1290-3. Epub 2013 Mar 10.

PMID:
23475757
[PubMed - indexed for MEDLINE]
5.

Molecular sequelae of histone deacetylase inhibition in human malignant B cells.

Mitsiades N, Mitsiades CS, Richardson PG, McMullan C, Poulaki V, Fanourakis G, Schlossman R, Chauhan D, Munshi NC, Hideshima T, Richon VM, Marks PA, Anderson KC.

Blood. 2003 May 15;101(10):4055-62. Epub 2003 Jan 16.

PMID:
12531799
[PubMed - indexed for MEDLINE]
Free Article
6.

The tricyclic antidepressant amitriptyline inhibits D-cyclin transactivation and induces myeloma cell apoptosis by inhibiting histone deacetylases: in vitro and in silico evidence.

Mao X, Hou T, Cao B, Wang W, Li Z, Chen S, Fei M, Hurren R, Gronda M, Wu D, Trudel S, Schimmer AD.

Mol Pharmacol. 2011 Apr;79(4):672-80. doi: 10.1124/mol.110.068122. Epub 2011 Jan 10.

PMID:
21220410
[PubMed - indexed for MEDLINE]
Free Article
7.

MGCD0103, a novel isotype-selective histone deacetylase inhibitor, has broad spectrum antitumor activity in vitro and in vivo.

Fournel M, Bonfils C, Hou Y, Yan PT, Trachy-Bourget MC, Kalita A, Liu J, Lu AH, Zhou NZ, Robert MF, Gillespie J, Wang JJ, Ste-Croix H, Rahil J, Lefebvre S, Moradei O, Delorme D, Macleod AR, Besterman JM, Li Z.

Mol Cancer Ther. 2008 Apr;7(4):759-68. doi: 10.1158/1535-7163.MCT-07-2026.

PMID:
18413790
[PubMed - indexed for MEDLINE]
Free Article
8.

Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.

Rajendran P, Delage B, Dashwood WM, Yu TW, Wuth B, Williams DE, Ho E, Dashwood RH.

Mol Cancer. 2011 May 30;10:68. doi: 10.1186/1476-4598-10-68.

PMID:
21624135
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Regulation of STAT3 by histone deacetylase-3 in diffuse large B-cell lymphoma: implications for therapy.

Gupta M, Han JJ, Stenson M, Wellik L, Witzig TE.

Leukemia. 2012 Jun;26(6):1356-64. doi: 10.1038/leu.2011.340. Epub 2011 Nov 25.

PMID:
22116549
[PubMed - indexed for MEDLINE]
Free PMC Article
10.
11.

Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer.

Wilson AJ, Byun DS, Popova N, Murray LB, L'Italien K, Sowa Y, Arango D, Velcich A, Augenlicht LH, Mariadason JM.

J Biol Chem. 2006 May 12;281(19):13548-58. Epub 2006 Mar 13.

PMID:
16533812
[PubMed - indexed for MEDLINE]
Free Article
12.

Mitochondrial apoptosis and FAK signaling disruption by a novel histone deacetylase inhibitor, HTPB, in antitumor and antimetastatic mouse models.

Shieh JM, Wei TT, Tang YA, Huang SM, Wen WL, Chen MY, Cheng HC, Salunke SB, Chen CS, Lin P, Chen CT, Wang YC.

PLoS One. 2012;7(1):e30240. doi: 10.1371/journal.pone.0030240. Epub 2012 Jan 18.

PMID:
22279574
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Type-specific roles of histone deacetylase (HDAC) overexpression in ovarian carcinoma: HDAC1 enhances cell proliferation and HDAC3 stimulates cell migration with downregulation of E-cadherin.

Hayashi A, Horiuchi A, Kikuchi N, Hayashi T, Fuseya C, Suzuki A, Konishi I, Shiozawa T.

Int J Cancer. 2010 Sep 1;127(6):1332-46. doi: 10.1002/ijc.25151.

PMID:
20049841
[PubMed - indexed for MEDLINE]
14.

Brazilin induces apoptosis and G2/M arrest via inactivation of histone deacetylase in multiple myeloma U266 cells.

Kim B, Kim SH, Jeong SJ, Sohn EJ, Jung JH, Lee MH, Kim SH.

J Agric Food Chem. 2012 Oct 3;60(39):9882-9. doi: 10.1021/jf302527p. Epub 2012 Sep 21.

PMID:
22967175
[PubMed - indexed for MEDLINE]
15.

HDAC3 influences phosphorylation of STAT3 at serine 727 by interacting with PP2A.

Togi S, Kamitani S, Kawakami S, Ikeda O, Muromoto R, Nanbo A, Matsuda T.

Biochem Biophys Res Commun. 2009 Feb 6;379(2):616-20. doi: 10.1016/j.bbrc.2008.12.132. Epub 2009 Jan 1.

PMID:
19121623
[PubMed - indexed for MEDLINE]
16.

The pan-histone deacetylase inhibitor CR2408 disrupts cell cycle progression, diminishes proliferation and causes apoptosis in multiple myeloma cells.

Baumann P, Junghanns C, Mandl-Weber S, Strobl S, Oduncu F, Schmidmaier R.

Br J Haematol. 2012 Mar;156(5):633-42. doi: 10.1111/j.1365-2141.2011.08983.x. Epub 2011 Dec 23.

PMID:
22211565
[PubMed - indexed for MEDLINE]
17.

Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications.

Mitsiades CS, Mitsiades NS, McMullan CJ, Poulaki V, Shringarpure R, Hideshima T, Akiyama M, Chauhan D, Munshi N, Gu X, Bailey C, Joseph M, Libermann TA, Richon VM, Marks PA, Anderson KC.

Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):540-5. Epub 2003 Dec 26.

PMID:
14695887
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Plant flavone apigenin inhibits HDAC and remodels chromatin to induce growth arrest and apoptosis in human prostate cancer cells: in vitro and in vivo study.

Pandey M, Kaur P, Shukla S, Abbas A, Fu P, Gupta S.

Mol Carcinog. 2012 Dec;51(12):952-62. doi: 10.1002/mc.20866. Epub 2011 Oct 17.

PMID:
22006862
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.

Catley L, Weisberg E, Tai YT, Atadja P, Remiszewski S, Hideshima T, Mitsiades N, Shringarpure R, LeBlanc R, Chauhan D, Munshi NC, Schlossman R, Richardson P, Griffin J, Anderson KC.

Blood. 2003 Oct 1;102(7):2615-22. Epub 2003 Jun 19.

PMID:
12816865
[PubMed - indexed for MEDLINE]
Free Article
20.

The coactivator role of histone deacetylase 3 in IL-1-signaling involves deacetylation of p65 NF-κB.

Ziesché E, Kettner-Buhrow D, Weber A, Wittwer T, Jurida L, Soelch J, Müller H, Newel D, Kronich P, Schneider H, Dittrich-Breiholz O, Bhaskara S, Hiebert SW, Hottiger MO, Li H, Burstein E, Schmitz ML, Kracht M.

Nucleic Acids Res. 2013 Jan 7;41(1):90-109. doi: 10.1093/nar/gks916. Epub 2012 Oct 19.

PMID:
23087373
[PubMed - indexed for MEDLINE]
Free PMC Article

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