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Results: 1 to 20 of 162

1.

Additional glycosylation within a specific hypervariable region of subtype 3a of hepatitis C virus protects against virus neutralization.

Anjum S, Wahid A, Afzal MS, Albecka A, Alsaleh K, Ahmad T, Baumert TF, Wychowski C, Qadri I, Penin F, Dubuisson J.

J Infect Dis. 2013 Dec 1;208(11):1888-97. doi: 10.1093/infdis/jit376. Epub 2013 Aug 1.

PMID:
23908491
[PubMed - indexed for MEDLINE]
2.

Mutations in hepatitis C virus E2 located outside the CD81 binding sites lead to escape from broadly neutralizing antibodies but compromise virus infectivity.

Keck ZY, Li SH, Xia J, von Hahn T, Balfe P, McKeating JA, Witteveldt J, Patel AH, Alter H, Rice CM, Foung SK.

J Virol. 2009 Jun;83(12):6149-60. doi: 10.1128/JVI.00248-09. Epub 2009 Mar 25.

PMID:
19321602
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Full-length characterization of hepatitis C virus subtype 3a reveals novel hypervariable regions under positive selection during acute infection.

Humphreys I, Fleming V, Fabris P, Parker J, Schulenberg B, Brown A, Demetriou C, Gaudieri S, Pfafferott K, Lucas M, Collier J, Huang KH, Pybus OG, Klenerman P, Barnes E.

J Virol. 2009 Nov;83(22):11456-66. doi: 10.1128/JVI.00884-09. Epub 2009 Sep 9. Erratum in: J Virol. 2010 Feb;84(3):1664.

PMID:
19740991
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The neutralizing activity of anti-hepatitis C virus antibodies is modulated by specific glycans on the E2 envelope protein.

Helle F, Goffard A, Morel V, Duverlie G, McKeating J, Keck ZY, Foung S, Penin F, Dubuisson J, Voisset C.

J Virol. 2007 Aug;81(15):8101-11. Epub 2007 May 23.

PMID:
17522218
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate.

Keck ZY, Xia J, Wang Y, Wang W, Krey T, Prentoe J, Carlsen T, Li AY, Patel AH, Lemon SM, Bukh J, Rey FA, Foung SK.

PLoS Pathog. 2012;8(4):e1002653. doi: 10.1371/journal.ppat.1002653. Epub 2012 Apr 12.

PMID:
22511875
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Neutralizing activities of caprine antibodies towards conserved regions of the HCV envelope glycoprotein E2.

El Abd YS, Tabll AA, El Din NG, Hosny Ael-D, Moustafa RI, El-Shenawy R, Atef K, El-Awady MK.

Virol J. 2011 Aug 5;8:391. doi: 10.1186/1743-422X-8-391.

PMID:
21819575
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Role of N-linked glycans in the functions of hepatitis C virus envelope proteins incorporated into infectious virions.

Helle F, Vieyres G, Elkrief L, Popescu CI, Wychowski C, Descamps V, Castelain S, Roingeard P, Duverlie G, Dubuisson J.

J Virol. 2010 Nov;84(22):11905-15. doi: 10.1128/JVI.01548-10. Epub 2010 Sep 15.

PMID:
20844034
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A point mutation at Asn-534 that disrupts a conserved N-glycosylation motif of the E2 glycoprotein of hepatitis C virus markedly enhances the sensitivity to antibody neutralization.

Sasayama M, Shoji I, Adianti M, Jiang DP, Deng L, Saito T, Watanabe H, Kawata S, Aoki C, Hotta H.

J Med Virol. 2012 Feb;84(2):229-34. doi: 10.1002/jmv.22257.

PMID:
22170542
[PubMed - indexed for MEDLINE]
9.

Human broadly neutralizing antibodies to the envelope glycoprotein complex of hepatitis C virus.

Giang E, Dorner M, Prentoe JC, Dreux M, Evans MJ, Bukh J, Rice CM, Ploss A, Burton DR, Law M.

Proc Natl Acad Sci U S A. 2012 Apr 17;109(16):6205-10. doi: 10.1073/pnas.1114927109. Epub 2012 Apr 4.

PMID:
22492964
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Naturally occurring antibodies that recognize linear epitopes in the amino terminus of the hepatitis C virus E2 protein confer noninterfering, additive neutralization.

Tarr AW, Urbanowicz RA, Jayaraj D, Brown RJ, McKeating JA, Irving WL, Ball JK.

J Virol. 2012 Mar;86(5):2739-49. doi: 10.1128/JVI.06492-11. Epub 2011 Dec 14.

PMID:
22171278
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Virus-neutralizing antibodies to hepatitis C virus.

Wahid A, Dubuisson J.

J Viral Hepat. 2013 Jun;20(6):369-76. doi: 10.1111/jvh.12094. Epub 2013 Apr 4. Review.

PMID:
23647953
[PubMed - indexed for MEDLINE]
12.

Hepatitis C virus E2 has three immunogenic domains containing conformational epitopes with distinct properties and biological functions.

Keck ZY, Op De Beeck A, Hadlock KG, Xia J, Li TK, Dubuisson J, Foung SK.

J Virol. 2004 Sep;78(17):9224-32.

PMID:
15308717
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Characterization of the hepatitis C virus E2 epitope defined by the broadly neutralizing monoclonal antibody AP33.

Tarr AW, Owsianka AM, Timms JM, McClure CP, Brown RJ, Hickling TP, Pietschmann T, Bartenschlager R, Patel AH, Ball JK.

Hepatology. 2006 Mar;43(3):592-601.

PMID:
16496330
[PubMed - indexed for MEDLINE]
14.

Inhibition of HCV 3a genotype entry through host CD81 and HCV E2 antibodies.

Ashfaq UA, Qasim M, Yousaf MZ, Awan MT, Jahan S.

J Transl Med. 2011 Nov 10;9:194. doi: 10.1186/1479-5876-9-194.

PMID:
22074322
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Glycan shifting on hepatitis C virus (HCV) E2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.

Pantua H, Diao J, Ultsch M, Hazen M, Mathieu M, McCutcheon K, Takeda K, Date S, Cheung TK, Phung Q, Hass P, Arnott D, Hongo JA, Matthews DJ, Brown A, Patel AH, Kelley RF, Eigenbrot C, Kapadia SB.

J Mol Biol. 2013 Jun 12;425(11):1899-914. doi: 10.1016/j.jmb.2013.02.025. Epub 2013 Feb 28.

PMID:
23458406
[PubMed - indexed for MEDLINE]
Free Article
16.

A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells.

Rosa D, Campagnoli S, Moretto C, Guenzi E, Cousens L, Chin M, Dong C, Weiner AJ, Lau JY, Choo QL, Chien D, Pileri P, Houghton M, Abrignani S.

Proc Natl Acad Sci U S A. 1996 Mar 5;93(5):1759-63.

PMID:
8700831
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Human combinatorial libraries yield rare antibodies that broadly neutralize hepatitis C virus.

Johansson DX, Voisset C, Tarr AW, Aung M, Ball JK, Dubuisson J, Persson MA.

Proc Natl Acad Sci U S A. 2007 Oct 9;104(41):16269-74. Epub 2007 Oct 2.

PMID:
17911260
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

A neutralization epitope in the hepatitis C virus E2 glycoprotein interacts with host entry factor CD81.

Zhao Z, Zhong L, Elrod E, Struble E, Ma L, Yan H, Harman C, Deng L, Virata-Theimer ML, Liu P, Alter H, Grakoui A, Zhang P.

PLoS One. 2014 Jan 6;9(1):e84346. doi: 10.1371/journal.pone.0084346. eCollection 2014.

PMID:
24400084
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Neutralizing host responses in hepatitis C virus infection target viral entry at postbinding steps and membrane fusion.

Haberstroh A, Schnober EK, Zeisel MB, Carolla P, Barth H, Blum HE, Cosset FL, Koutsoudakis G, Bartenschlager R, Union A, Depla E, Owsianka A, Patel AH, Schuster C, Stoll-Keller F, Doffoƫl M, Dreux M, Baumert TF.

Gastroenterology. 2008 Nov;135(5):1719-1728.e1. doi: 10.1053/j.gastro.2008.07.018. Epub 2008 Jul 22.

PMID:
18718838
[PubMed - indexed for MEDLINE]
20.

Broadly neutralizing human monoclonal antibodies to the hepatitis C virus E2 glycoprotein.

Owsianka AM, Tarr AW, Keck ZY, Li TK, Witteveldt J, Adair R, Foung SK, Ball JK, Patel AH.

J Gen Virol. 2008 Mar;89(Pt 3):653-9. doi: 10.1099/vir.0.83386-0.

PMID:
18272755
[PubMed - indexed for MEDLINE]
Free PMC Article

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