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Results: 1 to 20 of 99

1.

Targeted delivery of a phosphopeptide prodrug inhibits the proliferation of a human glioma cell line.

Kim SM, Yoon SM, Yim MS, Cho G, Ryu EK.

Amino Acids. 2013 Nov;45(5):1149-56. doi: 10.1007/s00726-013-1570-5. Epub 2013 Aug 2.

PMID:
23907439
[PubMed - indexed for MEDLINE]
2.

Phosphopeptides with improved cellular uptake properties as ligands for the polo-box domain of polo-like kinase 1.

Richter S, Neundorf I, Loebner K, Gräber M, Berg T, Bergmann R, Steinbach J, Pietzsch J, Wuest F.

Bioorg Med Chem Lett. 2011 Aug 15;21(16):4686-9. doi: 10.1016/j.bmcl.2011.06.103. Epub 2011 Jun 30.

PMID:
21778054
[PubMed - indexed for MEDLINE]
3.

In vivo tumor imaging using polo-box domain of polo-like kinase 1 targeted peptide.

Kim SM, Yoon S, Choi N, Hong KS, Murugan RN, Cho G, Ryu EK.

Biomaterials. 2012 Oct;33(29):6915-25. doi: 10.1016/j.biomaterials.2012.06.046. Epub 2012 Jul 15.

PMID:
22795848
[PubMed - indexed for MEDLINE]
4.

68Ga-1,4,7-Triazacyclononane-1,4,7-triacetic acid-c(RGDyK)-S-S-CPLHSpT.

Leung K.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2012 Aug 14 [updated 2012 Oct 25].

5.

Cell type-- dependent effects of Polo-like kinase 1 inhibition compared with targeted polo box interference in cancer cell lines.

Fink J, Sanders K, Rippl A, Finkernagel S, Beckers TL, Schmidt M.

Mol Cancer Ther. 2007 Dec;6(12 Pt 1):3189-97.

PMID:
18089713
[PubMed - indexed for MEDLINE]
Free Article
6.

[Targeting the substrate binding domain of polo-like kinase 1: advances in the study of PBD1 inhibitors].

Zhang L, Cao YH, Lu S, Sun SL, Liu HC, Lu T.

Yao Xue Xue Bao. 2013 Mar;48(3):315-24. Review. Chinese.

PMID:
23724641
[PubMed - indexed for MEDLINE]
7.

Polo-like kinase-1 as a novel target in neoplastic mast cells: demonstration of growth-inhibitory effects of small interfering RNA and the Polo-like kinase-1 targeting drug BI 2536.

Peter B, Gleixner KV, Cerny-Reiterer S, Herrmann H, Winter V, Hadzijusufovic E, Ferenc V, Schuch K, Mirkina I, Horny HP, Pickl WF, Müllauer L, Willmann M, Valent P.

Haematologica. 2011 May;96(5):672-80. doi: 10.3324/haematol.2010.031328. Epub 2011 Jan 17.

PMID:
21242189
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

Inhibiting Polo-like kinase 1 causes growth reduction and apoptosis in pediatric acute lymphoblastic leukemia cells.

Hartsink-Segers SA, Exalto C, Allen M, Williamson D, Clifford SC, Horstmann M, Caron HN, Pieters R, Den Boer ML.

Haematologica. 2013 Oct;98(10):1539-46. doi: 10.3324/haematol.2013.084434. Epub 2013 Jun 10.

PMID:
23753023
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Development of cyclic peptomer inhibitors targeting the polo-box domain of polo-like kinase 1.

Murugan RN, Park JE, Lim D, Ahn M, Cheong C, Kwon T, Nam KY, Choi SH, Kim BY, Yoon DY, Yaffe MB, Yu DY, Lee KS, Bang JK.

Bioorg Med Chem. 2013 May 1;21(9):2623-34. doi: 10.1016/j.bmc.2013.02.020. Epub 2013 Feb 27.

PMID:
23498919
[PubMed - indexed for MEDLINE]
10.

Polo-box domain inhibitor poloxin activates the spindle assembly checkpoint and inhibits tumor growth in vivo.

Yuan J, Sanhaji M, Krämer A, Reindl W, Hofmann M, Kreis NN, Zimmer B, Berg T, Strebhardt K.

Am J Pathol. 2011 Oct;179(4):2091-9. doi: 10.1016/j.ajpath.2011.06.031. Epub 2011 Aug 10.

PMID:
21839059
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity.

Rudolph D, Steegmaier M, Hoffmann M, Grauert M, Baum A, Quant J, Haslinger C, Garin-Chesa P, Adolf GR.

Clin Cancer Res. 2009 May 1;15(9):3094-102. doi: 10.1158/1078-0432.CCR-08-2445. Epub 2009 Apr 21.

PMID:
19383823
[PubMed - indexed for MEDLINE]
Free Article
12.

Inhibition of polo-like kinase 1 by blocking polo-box domain-dependent protein-protein interactions.

Reindl W, Yuan J, Krämer A, Strebhardt K, Berg T.

Chem Biol. 2008 May;15(5):459-66. doi: 10.1016/j.chembiol.2008.03.013.

PMID:
18482698
[PubMed - indexed for MEDLINE]
Free Article
13.

Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.

Harris PS, Venkataraman S, Alimova I, Birks DK, Donson AM, Knipstein J, Dubuc A, Taylor MD, Handler MH, Foreman NK, Vibhakar R.

BMC Cancer. 2012 Mar 5;12:80. doi: 10.1186/1471-2407-12-80.

PMID:
22390279
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

In vitro biological activity of a novel small-molecule inhibitor of polo-like kinase 1.

Lansing TJ, McConnell RT, Duckett DR, Spehar GM, Knick VB, Hassler DF, Noro N, Furuta M, Emmitte KA, Gilmer TM, Mook RA Jr, Cheung M.

Mol Cancer Ther. 2007 Feb;6(2):450-9. Epub 2007 Jan 31.

PMID:
17267659
[PubMed - indexed for MEDLINE]
Free Article
15.

A pan-specific inhibitor of the polo-box domains of polo-like kinases arrests cancer cells in mitosis.

Reindl W, Yuan J, Krämer A, Strebhardt K, Berg T.

Chembiochem. 2009 May 4;10(7):1145-8. doi: 10.1002/cbic.200900059.

PMID:
19350612
[PubMed - indexed for MEDLINE]
16.

Overexpression of polo-like kinase 1 and its clinical significance in human non-small cell lung cancer.

Wang ZX, Xue D, Liu ZL, Lu BB, Bian HB, Pan X, Yin YM.

Int J Biochem Cell Biol. 2012 Jan;44(1):200-10. doi: 10.1016/j.biocel.2011.10.017. Epub 2011 Nov 3.

PMID:
22064247
[PubMed - indexed for MEDLINE]
17.

Resistance to small molecule inhibitors of epidermal growth factor receptor in malignant gliomas.

Li B, Chang CM, Yuan M, McKenna WG, Shu HK.

Cancer Res. 2003 Nov 1;63(21):7443-50.

PMID:
14612544
[PubMed - indexed for MEDLINE]
Free Article
18.
19.

A high-throughput assay based on fluorescence polarization for inhibitors of the polo-box domain of polo-like kinase 1.

Reindl W, Strebhardt K, Berg T.

Anal Biochem. 2008 Dec 15;383(2):205-9. doi: 10.1016/j.ab.2008.08.014. Epub 2008 Aug 22.

PMID:
18793607
[PubMed - indexed for MEDLINE]
20.

Polo-like kinase 1 (Plk1) is expressed by cutaneous T-cell lymphomas (CTCLs), and its downregulation promotes cell cycle arrest and apoptosis.

Nihal M, Stutz N, Schmit T, Ahmad N, Wood GS.

Cell Cycle. 2011 Apr 15;10(8):1303-11. Epub 2011 Apr 15.

PMID:
21436619
[PubMed - indexed for MEDLINE]
Free Article

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