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Results: 1 to 20 of 110

1.

Ethanol administration produces divergent changes in GABAergic neuroactive steroid immunohistochemistry in the rat brain.

Cook JB, Dumitru AM, O'Buckley TK, Morrow AL.

Alcohol Clin Exp Res. 2014 Jan;38(1):90-9. doi: 10.1111/acer.12223. Epub 2013 Jul 26.

PMID:
23906006
[PubMed - in process]
2.

Ethanol alters local cellular levels of (3α,5α)-3-hydroxypregnan-20-one (3α,5α-THP) independent of the adrenals in subcortical brain regions.

Cook JB, Nelli SM, Neighbors MR, Morrow DH, O'Buckley TK, Maldonado-Devincci AM, Morrow AL.

Neuropsychopharmacology. 2014 Jul;39(8):1978-87. doi: 10.1038/npp.2014.46. Epub 2014 Feb 25.

PMID:
24566803
[PubMed - in process]
3.

Overexpression of the steroidogenic enzyme cytochrome P450 side chain cleavage in the ventral tegmental area increases 3α,5α-THP and reduces long-term operant ethanol self-administration.

Cook JB, Werner DF, Maldonado-Devincci AM, Leonard MN, Fisher KR, O'Buckley TK, Porcu P, McCown TJ, Besheer J, Hodge CW, Morrow AL.

J Neurosci. 2014 Apr 23;34(17):5824-34. doi: 10.1523/JNEUROSCI.4733-13.2014.

PMID:
24760842
[PubMed - indexed for MEDLINE]
4.

Evaluation of GABAergic neuroactive steroid 3alpha-hydroxy-5alpha-pregnane-20-one as a neurobiological substrate for the anti-anxiety effect of ethanol in rats.

Hirani K, Sharma AN, Jain NS, Ugale RR, Chopde CT.

Psychopharmacology (Berl). 2005 Jul;180(2):267-78. Epub 2005 Feb 18.

PMID:
15719223
[PubMed - indexed for MEDLINE]
5.

Neuroactive steroid 3 alpha-hydroxy-5 alpha-pregnan-20-one modulates ethanol-induced loss of righting reflex in rats.

Khisti RT, VanDoren MJ, O'Buckley T, Morrow AL.

Brain Res. 2003 Aug 8;980(2):255-65.

PMID:
12867266
[PubMed - indexed for MEDLINE]
6.

Reduction of circulating and selective limbic brain levels of (3α,5α)-3-hydroxy-pregnan-20-one (3α,5α-THP) following forced swim stress in C57BL/6J mice.

Maldonado-Devincci AM, Beattie MC, Morrow DH, McKinley RE, Cook JB, O'Buckley TK, Morrow AL.

Psychopharmacology (Berl). 2014 Sep;231(17):3281-92. doi: 10.1007/s00213-014-3552-z. Epub 2014 Apr 18.

PMID:
24744202
[PubMed - in process]
7.

Ethanol-induced elevation of 3 alpha-hydroxy-5 alpha-pregnan-20-one does not modulate motor incoordination in rats.

Khisti RT, VanDoren MJ, Matthews DB, Morrow AL.

Alcohol Clin Exp Res. 2004 Aug;28(8):1249-56.

PMID:
15318125
[PubMed - indexed for MEDLINE]
8.

Moderate doses of ethanol fail to increase plasma levels of neurosteroid 3alpha-hydroxy-5alpha-pregnan-20-one-like immunoreactivity in healthy men and women.

Holdstock L, Penland SN, Morrow AL, de Wit H.

Psychopharmacology (Berl). 2006 Jun;186(3):442-50. Epub 2005 Oct 21.

PMID:
16240164
[PubMed - indexed for MEDLINE]
9.

Neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one modulates electrophysiological and behavioral actions of ethanol.

VanDoren MJ, Matthews DB, Janis GC, Grobin AC, Devaud LL, Morrow AL.

J Neurosci. 2000 Mar 1;20(5):1982-9.

PMID:
10684899
[PubMed - indexed for MEDLINE]
Free Article
10.

Effects of chronic ethanol consumption and withdrawal on the neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one in male and female rats.

Janis GC, Devaud LL, Mitsuyama H, Morrow AL.

Alcohol Clin Exp Res. 1998 Dec;22(9):2055-61.

PMID:
9884151
[PubMed - indexed for MEDLINE]
11.

Differential effects of ethanol on serum GABAergic 3alpha,5alpha/3alpha,5beta neuroactive steroids in mice, rats, cynomolgus monkeys, and humans.

Porcu P, O'Buckley TK, Alward SE, Song SC, Grant KA, de Wit H, Leslie Morrow A.

Alcohol Clin Exp Res. 2010 Mar 1;34(3):432-42. doi: 10.1111/j.1530-0277.2009.01123.x. Epub 2009 Dec 17.

PMID:
20028362
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Role of acetaldehyde in ethanol-induced elevation of the neuroactive steroid 3alpha-hydroxy-5alpha-pregnan-20-one in rats.

Boyd KN, O'Buckley TK, Morrow AL.

Alcohol Clin Exp Res. 2008 Oct;32(10):1774-81. doi: 10.1111/j.1530-0277.2008.00762.x. Epub 2008 Jul 24.

PMID:
18652594
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Involvement of pregnane xenobiotic receptor in mating-induced allopregnanolone formation in the midbrain and hippocampus and brain-derived neurotrophic factor in the hippocampus among female rats.

Frye CA, Koonce CJ, Walf AA.

Psychopharmacology (Berl). 2014 Sep;231(17):3375-90. doi: 10.1007/s00213-014-3569-3. Epub 2014 May 1.

PMID:
24781516
[PubMed - in process]
14.

The pregnane xenobiotic receptor, a prominent liver factor, has actions in the midbrain for neurosteroid synthesis and behavioral/neural plasticity of female rats.

Frye CA, Koonce CJ, Walf AA.

Front Syst Neurosci. 2014 Apr 21;8:60. doi: 10.3389/fnsys.2014.00060. eCollection 2014.

PMID:
24795576
[PubMed]
Free PMC Article
15.

Differential change in neuroactive steroid sensitivity during ethanol withdrawal.

Finn DA, Gallaher EJ, Crabbe JC.

J Pharmacol Exp Ther. 2000 Jan;292(1):394-405.

PMID:
10604976
[PubMed - indexed for MEDLINE]
Free Article
16.

Perinatal neurosteroid levels influence GABAergic interneuron localization in adult rat prefrontal cortex.

Grobin AC, Heenan EJ, Lieberman JA, Morrow AL.

J Neurosci. 2003 Mar 1;23(5):1832-9.

PMID:
12629187
[PubMed - indexed for MEDLINE]
Free Article
17.

Chronic ethanol exposure produces tolerance to elevations in neuroactive steroids: mechanisms and reversal by exogenous ACTH.

Boyd KN, Kumar S, O'Buckley TK, Morrow AL.

J Neurochem. 2010 Oct;115(1):142-52. doi: 10.1111/j.1471-4159.2010.06904.x. Epub 2010 Jul 30.

PMID:
20633208
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Effects and Mechanisms of 3α,5α,-THP on Emotion, Motivation, and Reward Functions Involving Pregnane Xenobiotic Receptor.

Frye CA, Paris JJ, Walf AA, Rusconi JC.

Front Neurosci. 2012 Jan 19;5:136. doi: 10.3389/fnins.2011.00136. eCollection 2011.

PMID:
22294977
[PubMed]
Free PMC Article
20.

Motivated behaviors and levels of 3α,5α-THP in the midbrain are attenuated by knocking down expression of pregnane xenobiotic receptor in the midbrain ventral tegmental area of proestrous rats.

Frye CA, Koonce CJ, Walf AA, Rusconi JC.

J Sex Med. 2013 Jul;10(7):1692-706. doi: 10.1111/jsm.12173. Epub 2013 May 1.

PMID:
23634744
[PubMed - indexed for MEDLINE]
Free PMC Article

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