Format
Sort by

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 108

1.

A novel HDAC inhibitor OBP-801 and a PI3K inhibitor LY294002 synergistically induce apoptosis via the suppression of survivin and XIAP in renal cell carcinoma.

Yamada T, Horinaka M, Shinnoh M, Yoshioka T, Miki T, Sakai T.

Int J Oncol. 2013 Oct;43(4):1080-6. doi: 10.3892/ijo.2013.2042. Epub 2013 Jul 30.

PMID:
23900601
2.

Combination of a novel HDAC inhibitor OBP-801/YM753 and a PI3K inhibitor LY294002 synergistically induces apoptosis in human endometrial carcinoma cells due to increase of Bim with accumulation of ROS.

Yoshioka T, Yogosawa S, Yamada T, Kitawaki J, Sakai T.

Gynecol Oncol. 2013 May;129(2):425-32. doi: 10.1016/j.ygyno.2013.02.008. Epub 2013 Feb 9.

PMID:
23403163
3.

Inhibition of the PI3K/Akt pathway increases the chemosensitivity of gastric cancer to vincristine.

Xie X, Tang B, Zhou J, Gao Q, Zhang P.

Oncol Rep. 2013 Aug;30(2):773-82. doi: 10.3892/or.2013.2520. Epub 2013 Jun 5.

PMID:
23743572
4.

Phosphatidylinositol 3-kinase inhibition down-regulates survivin and facilitates TRAIL-mediated apoptosis in neuroblastomas.

Kim S, Kang J, Qiao J, Thomas RP, Evers BM, Chung DH.

J Pediatr Surg. 2004 Apr;39(4):516-21.

PMID:
15065019
5.

Arsenic trioxide induces apoptosis in NB-4, an acute promyelocytic leukemia cell line, through up-regulation of p73 via suppression of nuclear factor kappa B-mediated inhibition of p73 transcription and prevention of NF-kappaB-mediated induction of XIAP, cIAP2, BCL-XL and survivin.

Momeny M, Zakidizaji M, Ghasemi R, Dehpour AR, Rahimi-Balaei M, Abdolazimi Y, Ghavamzadeh A, Alimoghaddam K, Ghaffari SH.

Med Oncol. 2010 Sep;27(3):833-42. doi: 10.1007/s12032-009-9294-9. Epub 2009 Sep 10.

PMID:
19763917
6.

PI3K inhibition potentiates Bcl-2-dependent apoptosis in renal carcinoma cells.

Zhu S, Cohen MB, Bjorge JD, Mier JW, Cho DC.

J Cell Mol Med. 2013 Mar;17(3):377-85. doi: 10.1111/jcmm.12019. Epub 2013 Feb 7. Erratum in: J Cell Mol Med. 2014 Jul;18(7):1490.

7.

LY294002 and metformin cooperatively enhance the inhibition of growth and the induction of apoptosis of ovarian cancer cells.

Li C, Liu VW, Chan DW, Yao KM, Ngan HY.

Int J Gynecol Cancer. 2012 Jan;22(1):15-22. doi: 10.1097/IGC.0b013e3182322834.

PMID:
22080879
8.

Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.

Uddin S, Hussain AR, Al-Hussein KA, Manogaran PS, Wickrema A, Gutierrez MI, Bhatia KG.

Clin Cancer Res. 2005 Apr 15;11(8):3102-8.

9.
10.

A new selective AKT pharmacological inhibitor reduces resistance to chemotherapeutic drugs, TRAIL, all-trans-retinoic acid, and ionizing radiation of human leukemia cells.

Martelli AM, Tazzari PL, Tabellini G, Bortul R, Billi AM, Manzoli L, Ruggeri A, Conte R, Cocco L.

Leukemia. 2003 Sep;17(9):1794-805.

PMID:
12970779
12.

Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45.

Osaki M, Kase S, Adachi K, Takeda A, Hashimoto K, Ito H.

J Cancer Res Clin Oncol. 2004 Jan;130(1):8-14. Epub 2003 Nov 7.

PMID:
14605879
13.

Decitabine, a DNA methyltransferase inhibitor, induces apoptosis in human leukemia cells through intracellular reactive oxygen species generation.

Shin DY, Park YS, Yang K, Kim GY, Kim WJ, Han MH, Kang HS, Choi YH.

Int J Oncol. 2012 Sep;41(3):910-8. doi: 10.3892/ijo.2012.1546. Epub 2012 Jul 5.

PMID:
22767021
14.

Simultaneously targeting Bcl-2 and Akt pathways reverses resistance of nasopharyngeal carcinoma to TRAIL synergistically.

Li SS, Tang QL, Wang SH, Chen YH, Liu JJ, Yang XM.

Tumori. 2011 Nov-Dec;97(6):762-70. doi: 10.1700/1018.11094.

15.

Caffeic acid phenethyl ester suppresses melanoma tumor growth by inhibiting PI3K/AKT/XIAP pathway.

Pramanik KC, Kudugunti SK, Fofaria NM, Moridani MY, Srivastava SK.

Carcinogenesis. 2013 Sep;34(9):2061-70. doi: 10.1093/carcin/bgt154. Epub 2013 May 2.

18.

Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.

Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.

Eur J Pharmacol. 2007 Jun 1;563(1-3):49-60. Epub 2007 Feb 8.

PMID:
17341418
19.

Molecular mechanism of diclofenac-induced apoptosis of promyelocytic leukemia: dependency on reactive oxygen species, Akt, Bid, cytochrome and caspase pathway.

Inoue A, Muranaka S, Fujita H, Kanno T, Tamai H, Utsumi K.

Free Radic Biol Med. 2004 Oct 15;37(8):1290-9. Erratum in: Free Radic Biol Med. 2005 Jan 1;38(1):149.

PMID:
15451068
20.

The histone deacetylase inhibitor MS-275 interacts synergistically with fludarabine to induce apoptosis in human leukemia cells.

Maggio SC, Rosato RR, Kramer LB, Dai Y, Rahmani M, Paik DS, Czarnik AC, Payne SG, Spiegel S, Grant S.

Cancer Res. 2004 Apr 1;64(7):2590-600.

Items per page

Supplemental Content

Write to the Help Desk