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Items: 1 to 20 of 116


Nanoparticle drug loading as a design parameter to improve docetaxel pharmacokinetics and efficacy.

Chu KS, Schorzman AN, Finniss MC, Bowerman CJ, Peng L, Luft JC, Madden AJ, Wang AZ, Zamboni WC, DeSimone JM.

Biomaterials. 2013 Nov;34(33):8424-9. doi: 10.1016/j.biomaterials.2013.07.038. Epub 2013 Jul 27.


Development and optimization of oil-filled lipid nanoparticles containing docetaxel conjugates designed to control the drug release rate in vitro and in vivo.

Feng L, Wu H, Ma P, Mumper RJ, Benhabbour SR.

Int J Nanomedicine. 2011;6:2545-56. doi: 10.2147/IJN.S24954. Epub 2011 Oct 21.


Poly(lactide)-vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of Docetaxel.

Feng SS, Mei L, Anitha P, Gan CW, Zhou W.

Biomaterials. 2009 Jul;30(19):3297-306. doi: 10.1016/j.biomaterials.2009.02.045. Epub 2009 Mar 19.


Effect of drug release kinetics on nanoparticle therapeutic efficacy and toxicity.

Sethi M, Sukumar R, Karve S, Werner ME, Wang EC, Moore DT, Kowalczyk SR, Zhang L, Wang AZ.

Nanoscale. 2014 Feb 21;6(4):2321-7. doi: 10.1039/c3nr05961h. Epub 2014 Jan 14.


Practical preparation procedures for docetaxel-loaded nanoparticles using polylactic acid-co-glycolic acid.

Keum CG, Noh YW, Baek JS, Lim JH, Hwang CJ, Na YG, Shin SC, Cho CW.

Int J Nanomedicine. 2011;6:2225-34. doi: 10.2147/IJN.S24547. Epub 2011 Oct 7.


Antitumor activity of docetaxel-loaded polymeric nanoparticles fabricated by Shirasu porous glass membrane-emulsification technique.

Yu Y, Tan S, Zhao S, Zhuang X, Song Q, Wang Y, Zhou Q, Zhang Z.

Int J Nanomedicine. 2013;8:2641-52. doi: 10.2147/IJN.S48214. Epub 2013 Jul 29.


Plasma, tumor and tissue pharmacokinetics of Docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft.

Chu KS, Hasan W, Rawal S, Walsh MD, Enlow EM, Luft JC, Bridges AS, Kuijer JL, Napier ME, Zamboni WC, DeSimone JM.

Nanomedicine. 2013 Jul;9(5):686-93. doi: 10.1016/j.nano.2012.11.008. Epub 2012 Dec 6.


Preclinical development and clinical translation of a PSMA-targeted docetaxel nanoparticle with a differentiated pharmacological profile.

Hrkach J, Von Hoff D, Mukkaram Ali M, Andrianova E, Auer J, Campbell T, De Witt D, Figa M, Figueiredo M, Horhota A, Low S, McDonnell K, Peeke E, Retnarajan B, Sabnis A, Schnipper E, Song JJ, Song YH, Summa J, Tompsett D, Troiano G, Van Geen Hoven T, Wright J, LoRusso P, Kantoff PW, Bander NH, Sweeney C, Farokhzad OC, Langer R, Zale S.

Sci Transl Med. 2012 Apr 4;4(128):128ra39. doi: 10.1126/scitranslmed.3003651.


Folate-targeted polymeric nanoparticle formulation of docetaxel is an effective molecularly targeted radiosensitizer with efficacy dependent on the timing of radiotherapy.

Werner ME, Copp JA, Karve S, Cummings ND, Sukumar R, Li C, Napier ME, Chen RC, Cox AD, Wang AZ.

ACS Nano. 2011 Nov 22;5(11):8990-8. doi: 10.1021/nn203165z. Epub 2011 Oct 28.


In vitro and in vivo evaluation of folate receptor-targeting amphiphilic copolymer-modified liposomes loaded with docetaxel.

Li X, Tian X, Zhang J, Zhao X, Chen X, Jiang Y, Wang D, Pan W.

Int J Nanomedicine. 2011;6:1167-84. doi: 10.2147/IJN.S21445. Epub 2011 Jun 9.


Docetaxel-loaded polylactic acid-co-glycolic acid nanoparticles: formulation, physicochemical characterization and cytotoxicity studies.

Pradhan R, Poudel BK, Ramasamy T, Choi HG, Yong CS, Kim JO.

J Nanosci Nanotechnol. 2013 Aug;13(8):5948-56.


Long circulating PEGylated poly(D,L-lactide-co-glycolide) nanoparticulate delivery of Docetaxel to solid tumors.

Senthilkumar M, Mishra P, Jain NK.

J Drug Target. 2008 Jun;16(5):424-35. doi: 10.1080/10611860802088598 .


Oil-filled lipid nanoparticles containing 2'-(2-bromohexadecanoyl)-docetaxel for the treatment of breast cancer.

Feng L, Benhabbour SR, Mumper RJ.

Adv Healthc Mater. 2013 Nov;2(11):1451-7. doi: 10.1002/adhm.201300017. Epub 2013 Apr 19.


Differential cell responses to nanoparticle docetaxel and small molecule docetaxel at a sub-therapeutic dose range.

Wang EC, Sinnott R, Werner ME, Sethi M, Whitehurst AW, Wang AZ.

Nanomedicine. 2014 Feb;10(2):321-8. doi: 10.1016/j.nano.2013.07.012. Epub 2013 Aug 3.


A novel lipid-based nanomicelle of docetaxel: evaluation of antitumor activity and biodistribution.

Ma M, Hao Y, Liu N, Yin Z, Wang L, Liang X, Zhang X.

Int J Nanomedicine. 2012;7:3389-98. doi: 10.2147/IJN.S29827. Epub 2012 Jul 4.


Cholic acid-functionalized nanoparticles of star-shaped PLGA-vitamin E TPGS copolymer for docetaxel delivery to cervical cancer.

Zeng X, Tao W, Mei L, Huang L, Tan C, Feng SS.

Biomaterials. 2013 Aug;34(25):6058-67. doi: 10.1016/j.biomaterials.2013.04.052. Epub 2013 May 18.


Potent engineered PLGA nanoparticles by virtue of exceptionally high chemotherapeutic loadings.

Enlow EM, Luft JC, Napier ME, DeSimone JM.

Nano Lett. 2011 Feb 9;11(2):808-13. doi: 10.1021/nl104117p. Epub 2011 Jan 25.


Polyelectrolyte coated polymeric nanoparticles for controlled release of docetaxel.

Agrawal R, Shanavas A, Yadav S, Aslam M, Bahadur D, Srivastava R.

J Biomed Nanotechnol. 2012 Feb;8(1):19-28.


Formulation of functionalized PLGA-PEG nanoparticles for in vivo targeted drug delivery.

Cheng J, Teply BA, Sherifi I, Sung J, Luther G, Gu FX, Levy-Nissenbaum E, Radovic-Moreno AF, Langer R, Farokhzad OC.

Biomaterials. 2007 Feb;28(5):869-76. Epub 2006 Oct 20.

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