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Items: 1 to 20 of 152

1.

SHANK3 gene mutations associated with autism facilitate ligand binding to the Shank3 ankyrin repeat region.

Mameza MG, Dvoretskova E, Bamann M, Hönck HH, Güler T, Boeckers TM, Schoen M, Verpelli C, Sala C, Barsukov I, Dityatev A, Kreienkamp HJ.

J Biol Chem. 2013 Sep 13;288(37):26697-708. doi: 10.1074/jbc.M112.424747. Epub 2013 Jul 29.

2.

Autism-associated mutations in ProSAP2/Shank3 impair synaptic transmission and neurexin-neuroligin-mediated transsynaptic signaling.

Arons MH, Thynne CJ, Grabrucker AM, Li D, Schoen M, Cheyne JE, Boeckers TM, Montgomery JM, Garner CC.

J Neurosci. 2012 Oct 24;32(43):14966-78. doi: 10.1523/JNEUROSCI.2215-12.2012.

3.

Sharpin, a novel postsynaptic density protein that directly interacts with the shank family of proteins.

Lim S, Sala C, Yoon J, Park S, Kuroda S, Sheng M, Kim E.

Mol Cell Neurosci. 2001 Feb;17(2):385-97.

PMID:
11178875
4.

Synaptic scaffolding proteins in rat brain. Ankyrin repeats of the multidomain Shank protein family interact with the cytoskeletal protein alpha-fodrin.

Böckers TM, Mameza MG, Kreutz MR, Bockmann J, Weise C, Buck F, Richter D, Gundelfinger ED, Kreienkamp HJ.

J Biol Chem. 2001 Oct 26;276(43):40104-12. Epub 2001 Aug 16.

5.

SHANK3 mutations identified in autism lead to modification of dendritic spine morphology via an actin-dependent mechanism.

Durand CM, Perroy J, Loll F, Perrais D, Fagni L, Bourgeron T, Montcouquiol M, Sans N.

Mol Psychiatry. 2012 Jan;17(1):71-84. doi: 10.1038/mp.2011.57. Epub 2011 May 24.

6.

Zinc deficiency dysregulates the synaptic ProSAP/Shank scaffold and might contribute to autism spectrum disorders.

Grabrucker S, Jannetti L, Eckert M, Gaub S, Chhabra R, Pfaender S, Mangus K, Reddy PP, Rankovic V, Schmeisser MJ, Kreutz MR, Ehret G, Boeckers TM, Grabrucker AM.

Brain. 2014 Jan;137(Pt 1):137-52. doi: 10.1093/brain/awt303. Epub 2013 Nov 25.

7.

Linkage of the actin cytoskeleton to the postsynaptic density via direct interactions of Abp1 with the ProSAP/Shank family.

Qualmann B, Boeckers TM, Jeromin M, Gundelfinger ED, Kessels MM.

J Neurosci. 2004 Mar 10;24(10):2481-95. Erratum in: J Neurosci. 2004 Apr 14;24(15):following 3849.

8.

Enhanced polyubiquitination of Shank3 and NMDA receptor in a mouse model of autism.

Bangash MA, Park JM, Melnikova T, Wang D, Jeon SK, Lee D, Syeda S, Kim J, Kouser M, Schwartz J, Cui Y, Zhao X, Speed HE, Kee SE, Tu JC, Hu JH, Petralia RS, Linden DJ, Powell CM, Savonenko A, Xiao B, Worley PF.

Cell. 2011 May 27;145(5):758-72. doi: 10.1016/j.cell.2011.03.052. Epub 2011 May 12. Retraction in: Cell. 2013 Jan 17;152(1-2):367.

9.

The Shank family of postsynaptic density proteins interacts with and promotes synaptic accumulation of the beta PIX guanine nucleotide exchange factor for Rac1 and Cdc42.

Park E, Na M, Choi J, Kim S, Lee JR, Yoon J, Park D, Sheng M, Kim E.

J Biol Chem. 2003 May 23;278(21):19220-9. Epub 2003 Mar 7.

10.

Characterization of an ankyrin repeat-containing Shank2 isoform (Shank2E) in liver epithelial cells.

McWilliams RR, Gidey E, Fouassier L, Weed SA, Doctor RB.

Biochem J. 2004 May 15;380(Pt 1):181-91.

11.

Shank3 is localized in axons and presynaptic specializations of developing hippocampal neurons and involved in the modulation of NMDA receptor levels at axon terminals.

Halbedl S, Schoen M, Feiler MS, Boeckers TM, Schmeisser MJ.

J Neurochem. 2016 Apr;137(1):26-32. doi: 10.1111/jnc.13523. Epub 2016 Jan 24.

PMID:
26725465
12.

Reduced excitatory neurotransmission and mild autism-relevant phenotypes in adolescent Shank3 null mutant mice.

Yang M, Bozdagi O, Scattoni ML, Wöhr M, Roullet FI, Katz AM, Abrams DN, Kalikhman D, Simon H, Woldeyohannes L, Zhang JY, Harris MJ, Saxena R, Silverman JL, Buxbaum JD, Crawley JN.

J Neurosci. 2012 May 9;32(19):6525-41. doi: 10.1523/JNEUROSCI.6107-11.2012.

13.

A functional role of postsynaptic density-95-guanylate kinase-associated protein complex in regulating Shank assembly and stability to synapses.

Romorini S, Piccoli G, Jiang M, Grossano P, Tonna N, Passafaro M, Zhang M, Sala C.

J Neurosci. 2004 Oct 20;24(42):9391-404.

14.

A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins.

Suzuki T, Li W, Zhang JP, Tian QB, Sakagami H, Usuda N, Kondo H, Fujii T, Endo S.

Eur J Neurosci. 2005 Jan;21(2):339-50. Erratum in: Eur J Neurosci. 2005 Feb;21(3):825. Usada, Nobuteru [corrected to Usuda, Nobuteru].

PMID:
15673434
15.

Postsynaptic shank antagonizes dendrite branching induced by the leucine-rich repeat protein Densin-180.

Quitsch A, Berhörster K, Liew CW, Richter D, Kreienkamp HJ.

J Neurosci. 2005 Jan 12;25(2):479-87.

16.

Modeling autism by SHANK gene mutations in mice.

Jiang YH, Ehlers MD.

Neuron. 2013 Apr 10;78(1):8-27. doi: 10.1016/j.neuron.2013.03.016. Review.

17.

The PSD protein ProSAP2/Shank3 displays synapto-nuclear shuttling which is deregulated in a schizophrenia-associated mutation.

Grabrucker S, Proepper C, Mangus K, Eckert M, Chhabra R, Schmeisser MJ, Boeckers TM, Grabrucker AM.

Exp Neurol. 2014 Mar;253:126-37. doi: 10.1016/j.expneurol.2013.12.015. Epub 2013 Dec 29.

PMID:
24382453
18.

A role for synaptic zinc in ProSAP/Shank PSD scaffold malformation in autism spectrum disorders.

Grabrucker AM.

Dev Neurobiol. 2014 Feb;74(2):136-46. doi: 10.1002/dneu.22089. Epub 2013 Sep 11. Review.

19.

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication.

Bozdagi O, Sakurai T, Papapetrou D, Wang X, Dickstein DL, Takahashi N, Kajiwara Y, Yang M, Katz AM, Scattoni ML, Harris MJ, Saxena R, Silverman JL, Crawley JN, Zhou Q, Hof PR, Buxbaum JD.

Mol Autism. 2010 Dec 17;1(1):15. doi: 10.1186/2040-2392-1-15.

20.

Direct interaction of post-synaptic density-95/Dlg/ZO-1 domain-containing synaptic molecule Shank3 with GluR1 alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor.

Uchino S, Wada H, Honda S, Nakamura Y, Ondo Y, Uchiyama T, Tsutsumi M, Suzuki E, Hirasawa T, Kohsaka S.

J Neurochem. 2006 May;97(4):1203-14. Epub 2006 Apr 5.

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