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Results: 1 to 20 of 114

1.

Development of a validated liquid chromatography tandem mass spectrometry assay for a PEGylated adnectin in cynomolgus monkey plasma using protein precipitation and trypsin digestion.

Dawes ML, Gu H, Wang J, Schuster AE, Haulenbeek J.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Sep 1;934:1-7. doi: 10.1016/j.jchromb.2013.06.027. Epub 2013 Jul 11.

PMID:
23891912
[PubMed - indexed for MEDLINE]
3.
4.

Attribution of the discrepancy between ELISA and LC-MS/MS assay results of a PEGylated scaffold protein in post-dose monkey plasma samples due to the presence of anti-drug antibodies.

Wang SJ, Wu ST, Gokemeijer J, Fura A, Krishna M, Morin P, Chen G, Price K, Wang-Iverson D, Olah T, Weiner R, Tymiak A, Jemal M.

Anal Bioanal Chem. 2012 Jan;402(3):1229-39. doi: 10.1007/s00216-011-5527-9. Epub 2011 Dec 1.

PMID:
22130720
[PubMed - indexed for MEDLINE]
5.

Quantitation of therapeutic proteins following direct trypsin digestion of dried blood spot samples and detection by LC-MS-based bioanalytical methods in drug discovery.

Sleczka BG, D'Arienzo CJ, Tymiak AA, Olah TV.

Bioanalysis. 2012 Jan;4(1):29-40. doi: 10.4155/bio.11.293.

PMID:
22191592
[PubMed - indexed for MEDLINE]
6.

Direct quantitative analysis of a 20 kDa PEGylated human calcitonin gene peptide antagonist in cynomolgus monkey serum using in-source CID and UPLC-MS/MS.

Li H, Rose MJ, Holder JR, Wright M, Miranda LP, James CA.

J Am Soc Mass Spectrom. 2011 Sep;22(9):1660-7. doi: 10.1007/s13361-011-0180-2. Epub 2011 Jun 23.

PMID:
21953269
[PubMed - indexed for MEDLINE]
7.

Fully validated LC-MS/MS assay for the simultaneous quantitation of coadministered therapeutic antibodies in cynomolgus monkey serum.

Jiang H, Zeng J, Titsch C, Voronin K, Akinsanya B, Luo L, Shen H, Desai DD, Allentoff A, Aubry AF, Desilva BS, Arnold ME.

Anal Chem. 2013 Oct 15;85(20):9859-67. doi: 10.1021/ac402420v. Epub 2013 Sep 26.

PMID:
24024648
[PubMed - indexed for MEDLINE]
8.

Quantification of Alefacept, an immunosuppressive fusion protein in human plasma using a protein analogue internal standard, trypsin cleaved signature peptides and liquid chromatography tandem mass spectrometry.

Halquist MS, Karnes HT.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Apr 1;879(11-12):789-98. doi: 10.1016/j.jchromb.2011.02.034. Epub 2011 Feb 25.

PMID:
21397570
[PubMed - indexed for MEDLINE]
9.

Comparison of bioanalytical methods for the quantitation of PEGylated human insulin.

de Dios K, Manibusan A, Marsden R, Pinkstaff J.

J Immunol Methods. 2013 Oct 31;396(1-2):1-7. doi: 10.1016/j.jim.2013.07.007. Epub 2013 Aug 6.

PMID:
23933323
[PubMed - indexed for MEDLINE]
10.

Liquid-liquid extraction of strongly protein bound BMS-299897 from human plasma and cerebrospinal fluid, followed by high-performance liquid chromatography/tandem mass spectrometry.

Xue YJ, Pursley J, Arnold M.

J Pharm Biomed Anal. 2007 Apr 11;43(5):1728-36. Epub 2007 Jan 3.

PMID:
17204392
[PubMed - indexed for MEDLINE]
11.

Simultaneous determination of a p38 MAP kinase inhibitor and its amide hydrolyzed metabolite in Cynomolgus monkey plasma by LC-MS/MS, and its application to a toxicokinetic study.

Akrami A, Hsieh F, Almon V, Bruenner BA, James C, Wong P.

J Pharm Biomed Anal. 2011 Jul 15;55(5):1104-10. doi: 10.1016/j.jpba.2011.03.022. Epub 2011 Mar 21.

PMID:
21481559
[PubMed - indexed for MEDLINE]
12.

Determination of ticagrelor and two metabolites in plasma samples by liquid chromatography and mass spectrometry.

Sillén H, Cook M, Davis P.

J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Sep 1;878(25):2299-306. doi: 10.1016/j.jchromb.2010.06.018. Epub 2010 Jun 25.

PMID:
20688583
[PubMed - indexed for MEDLINE]
13.
14.

A 96-well single-pot protein precipitation, liquid chromatography/tandem mass spectrometry (LC/MS/MS) method for the determination of muraglitazar, a novel diabetes drug, in human plasma.

Xue YJ, Liu J, Pursley J, Unger S.

J Chromatogr B Analyt Technol Biomed Life Sci. 2006 Feb 2;831(1-2):213-22. Epub 2006 Jan 18.

PMID:
16388995
[PubMed - indexed for MEDLINE]
15.

A rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the estimation of amlodipine in human plasma.

Bhatt J, Singh S, Subbaiah G, Shah B, Kambli S, Ameta S.

Biomed Chromatogr. 2007 Feb;21(2):169-75.

PMID:
17221911
[PubMed - indexed for MEDLINE]
16.

A highly sensitive and selective method for the determination of leukotriene B4 (LTB4) in ex vivo stimulated human plasma by ultra fast liquid chromatography-tandem mass spectrometry.

Lin W, Huang MQ, Xue X, Bertelsen K, Chen G, Zhao H, Lin ZJ, Fourie A, de Jong J, Weng N.

J Chromatogr B Analyt Technol Biomed Life Sci. 2013 Apr 15;925:54-62. doi: 10.1016/j.jchromb.2013.02.038. Epub 2013 Mar 8.

PMID:
23523878
[PubMed - indexed for MEDLINE]
17.

Bioanalytical method development and validation of novel antithrombotic agent S002-333 by LC-MS/MS and its application to pharmacokinetic studies.

Bhatta RS, Kumar D, Chhonker YS, Saxena AK, Jain GK.

Biomed Chromatogr. 2010 Nov;24(11):1234-9. doi: 10.1002/bmc.1433.

PMID:
20954216
[PubMed - indexed for MEDLINE]
18.

Buprenorphine and norbuprenorphine quantification in human plasma by simple protein precipitation and ultra-high performance liquid chromatography tandem mass spectrometry.

Lüthi G, Blangy V, Eap CB, Ansermot N.

J Pharm Biomed Anal. 2013 Apr 15;77:1-8. doi: 10.1016/j.jpba.2012.12.023. Epub 2012 Dec 28.

PMID:
23357637
[PubMed - indexed for MEDLINE]
19.

Highly specific and sensitive measurements of human and monkey interleukin 21 using sequential protein and tryptic peptide immunoaffinity LC-MS/MS.

Palandra J, Finelli A, Zhu M, Masferrer J, Neubert H.

Anal Chem. 2013 Jun 4;85(11):5522-9. doi: 10.1021/ac4006765. Epub 2013 May 16.

PMID:
23638938
[PubMed - indexed for MEDLINE]
20.

Simultaneous determination of ribavirin and ribavirin base in monkey plasma by high performance liquid chromatography with tandem mass spectrometry.

Li W, Luo S, Li S, Athill L, Wu A, Ray T, Zhou W, Ke J, Smith HT, Tse FL.

J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Feb 1;846(1-2):57-68. Epub 2006 Sep 7.

PMID:
16962398
[PubMed - indexed for MEDLINE]

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